Click here to switch to the map view.

The map label for this gene is slyD [H]

Identifier: 21243480

GI number: 21243480

Start: 3225709

End: 3226188

Strand: Reverse

Name: slyD [H]

Synonym: XAC2754

Alternate gene names: 21243480

Gene position: 3226188-3225709 (Counterclockwise)

Preceding gene: 21243483

Following gene: 21243479

Centisome position: 62.34

GC content: 62.29

Gene sequence:

>480_bases
ATGAAGATCGAAAAAGACAGCGTCGTCCGCTTCCATTACACCGTTTCGGAGATCGGCCAGGAGCCGATCGAGAGCTCCAA
GGAGCGTGACCCGTTGGCGATCATGATCGGCCACGGCAACATCATCCCGGGCCTGGAAGCGGCCATGATGGATAAGGAAG
CCGGCGAGAGCTTCGGCGTTGACGTCAAGGCCACCGAAGCCTATGGCGAATACCGCGAAGGCCTGAGCCAGCGCGTGCCC
AAGAAGCATTTCGGCGCCACCAAGCTGGTGCCCGGCACCCAGGTCGTGCTGCAGACCAACTTCGGCCCGCGCGCGGTGAC
GGTGCAGAAGGTCGGCATGAGCGTGGTCGATGTGGACCTCAATCACCCGATGGCCGGCAAGGATCTGCATTTCGACGTGG
AGATCGTCGAAGTGCGCGAAGCCACCGCGGAAGAACGCGACCACGGCCATGTGCACGGCGACGGCGGTCATCACCACTAA

Upstream 100 bases:

>100_bases
ATAATGGGCGGTTCGAAAGGTCGCCATGATGGCGGCGCACCCGGCGGCCGACAAGCCGTCCTCAACCGTCTGCCACCGGG
CAGCCCATTCAGAGCCAGGC

Downstream 100 bases:

>100_bases
GGTCGGTCACGCACGCACGCGCTCGCGTGGCGGTTGGACGGATGGGACGCATGCGCACCACTGACGTAGGCCGGCCATCC
GGCGCGACGGTGGTGCATGC

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKIEKDSVVRFHYTVSEIGQEPIESSKERDPLAIMIGHGNIIPGLEAAMMDKEAGESFGVDVKATEAYGEYREGLSQRVP
KKHFGATKLVPGTQVVLQTNFGPRAVTVQKVGMSVVDVDLNHPMAGKDLHFDVEIVEVREATAEERDHGHVHGDGGHHH

Sequences:

>Translated_159_residues
MKIEKDSVVRFHYTVSEIGQEPIESSKERDPLAIMIGHGNIIPGLEAAMMDKEAGESFGVDVKATEAYGEYREGLSQRVP
KKHFGATKLVPGTQVVLQTNFGPRAVTVQKVGMSVVDVDLNHPMAGKDLHFDVEIVEVREATAEERDHGHVHGDGGHHH
>Mature_159_residues
MKIEKDSVVRFHYTVSEIGQEPIESSKERDPLAIMIGHGNIIPGLEAAMMDKEAGESFGVDVKATEAYGEYREGLSQRVP
KKHFGATKLVPGTQVVLQTNFGPRAVTVQKVGMSVVDVDLNHPMAGKDLHFDVEIVEVREATAEERDHGHVHGDGGHHH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=146, Percent_Identity=43.1506849315069, Blast_Score=102, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17444; Mature: 17444

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEKDSVVRFHYTVSEIGQEPIESSKERDPLAIMIGHGNIIPGLEAAMMDKEAGESFGV
CCCCCCCEEEEEEEHHHHCCCHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCC
DVKATEAYGEYREGLSQRVPKKHFGATKLVPGTQVVLQTNFGPRAVTVQKVGMSVVDVDL
EEEEHHHHHHHHHHHHHCCCHHHCCCEECCCCCEEEEEECCCCCEEEHHHCCCEEEEEEC
NHPMAGKDLHFDVEIVEVREATAEERDHGHVHGDGGHHH
CCCCCCCCEEEEEEEEEEHHHHHHHCCCCCEECCCCCCC
>Mature Secondary Structure
MKIEKDSVVRFHYTVSEIGQEPIESSKERDPLAIMIGHGNIIPGLEAAMMDKEAGESFGV
CCCCCCCEEEEEEEHHHHCCCHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCC
DVKATEAYGEYREGLSQRVPKKHFGATKLVPGTQVVLQTNFGPRAVTVQKVGMSVVDVDL
EEEEHHHHHHHHHHHHHCCCHHHCCCEECCCCCEEEEEECCCCCEEEHHHCCCEEEEEEC
NHPMAGKDLHFDVEIVEVREATAEERDHGHVHGDGGHHH
CCCCCCCCEEEEEEEEEEHHHHHHHCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]