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The map label for this gene is aroC

Identifier: 21243452

GI number: 21243452

Start: 3186507

End: 3187610

Strand: Reverse

Name: aroC

Synonym: XAC2725

Alternate gene names: 21243452

Gene position: 3187610-3186507 (Counterclockwise)

Preceding gene: 21243453

Following gene: 21243451

Centisome position: 61.59

GC content: 67.12

Gene sequence:

>1104_bases
ATGAGTGCCAATTCGTTCGGCAAGCTGTTCACTGTCACCACCTTTGGCGAATCGCACGGGCCGGCGATCGGCTGCGTCGT
CGACGGCTGCCCTCCCGGCCTGGAGATTGCGCCGGAAGAGTTCACCCACGATCTGCAGCGCCGTGCCAGCGGCAAGAGCC
GGCACACCTCGGCGCGCCGCGAGGCCGATGAGATCGAGATCCTGTCCGGCGTGTACGAAGGCCGTACCACCGGCACGCCG
ATCGGCTTGCTGATCCGCAATACCGATCAGCGCAGCAAGGATTACAGCAACATCGCCCAGCAGTTCCGTCCGGGCCATGC
GGATTACACCTACTGGCAGAAGTACGGCATTCGCGATCCGCGCGGCGGCGGGCGCTCGTCGGCGCGCGAAACCACCATGC
GCGTCGCCGCGGGCGTGATCGCCAAGAAGTGGCTCAAGCAACGGTATGGCGTGCTGGTGCGCGGGTTCCTGTCGCAGCTG
GGCGAGATCCGTCCCGCTGGTTTCGACTGGGATGCGGTGGAAGACAACCCGTTTTTCTGGCCGCATGCCGCGCAGGTGCC
GGAGCTGGAAACCTATATGGACGCGCTGCGTAAATCCGGCGATTCGGTCGGTGCGCGCGTGGACGTGGTGGCCGGCGGCG
TGCCCGCAGGCTGGGGCGAGCCGATCTACGGCAAGCTCGATGCCGAACTTGCCGCTGCGTTGATGAGCATCAATGCGGTC
AAGGGCGTGGAGATCGGCGACGGCTTCGCCAGCGCCGCGCAGAGGGGCACCGAACACCGCGACCTGATCACCCCGGAAGG
CTTTCTCAGCAACCATGCCGGCGGCATCCTGGGCGGGATCTCCACTGGCCAGGCGGTCACCGCCTCGATGGTGCTCAAGC
CCACCTCCAGCCTGCGCCTGCCCGGCGCCACGGTGGATGCCGATGGCAGCGTGGTCGATGTGATCACCACCGGCCGGCAC
GACCCGTGCGTGGGCATCCGCGCCACCCCGATCGCCGAGGCGATGATGGCGCTGGTGCTGATGGACCAGGCGCTGCGCCA
CCGTGCGCAGTGCGGCGATGTAGGTGAGGTGTCGCCGCGCATTCCCGGTCAGGTCGATGTCTGA

Upstream 100 bases:

>100_bases
AAGGTCGGGCAGATGGGCATCTTCGCGGTGGAATGCCGCGAATTGATCGCCCACGGCGCCCGCATCGCCGAGCTGGCCGC
GCAGCGATGAGCCTGCGCGC

Downstream 100 bases:

>100_bases
CGGCCGTCGCGCCAGGGTGTGGGTCAGCCAGCCGTTGTTCGACGATGTCGTCGCGCAGCTGGGCGAGCATTTCGAGCTGA
CCACCACGCAGCGCGTCAGC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSANSFGKLFTVTTFGESHGPAIGCVVDGCPPGLEIAPEEFTHDLQRRASGKSRHTSARREADEIEILSGVYEGRTTGTP
IGLLIRNTDQRSKDYSNIAQQFRPGHADYTYWQKYGIRDPRGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQL
GEIRPAGFDWDAVEDNPFFWPHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPAGWGEPIYGKLDAELAAALMSINAV
KGVEIGDGFASAAQRGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRLPGATVDADGSVVDVITTGRH
DPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPRIPGQVDV

Sequences:

>Translated_367_residues
MSANSFGKLFTVTTFGESHGPAIGCVVDGCPPGLEIAPEEFTHDLQRRASGKSRHTSARREADEIEILSGVYEGRTTGTP
IGLLIRNTDQRSKDYSNIAQQFRPGHADYTYWQKYGIRDPRGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQL
GEIRPAGFDWDAVEDNPFFWPHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPAGWGEPIYGKLDAELAAALMSINAV
KGVEIGDGFASAAQRGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRLPGATVDADGSVVDVITTGRH
DPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPRIPGQVDV
>Mature_366_residues
SANSFGKLFTVTTFGESHGPAIGCVVDGCPPGLEIAPEEFTHDLQRRASGKSRHTSARREADEIEILSGVYEGRTTGTPI
GLLIRNTDQRSKDYSNIAQQFRPGHADYTYWQKYGIRDPRGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQLG
EIRPAGFDWDAVEDNPFFWPHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPAGWGEPIYGKLDAELAAALMSINAVK
GVEIGDGFASAAQRGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRLPGATVDADGSVVDVITTGRHD
PCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPRIPGQVDV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=63.3333333333333, Blast_Score=447, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6321290, Length=371, Percent_Identity=41.2398921832884, Blast_Score=268, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_XANAC (Q8PJ20)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_643034.1
- ProteinModelPortal:   Q8PJ20
- SMR:   Q8PJ20
- GeneID:   1156796
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2725
- NMPDR:   fig|190486.1.peg.2678
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- BioCyc:   XAXO190486:XAC2725-MONOMER
- BRENDA:   4.2.3.5
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39140; Mature: 39008

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANSFGKLFTVTTFGESHGPAIGCVVDGCPPGLEIAPEEFTHDLQRRASGKSRHTSARR
CCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
EADEIEILSGVYEGRTTGTPIGLLIRNTDQRSKDYSNIAQQFRPGHADYTYWQKYGIRDP
HHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQLGEIRPAGFDWDAVEDNPFFW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPAGWGEPIYGKLDAELAAALMSINAV
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KGVEIGDGFASAAQRGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRL
CCCCCCCHHHHHHHCCCCCCCCCCCCHHHHCCCCCEEECCCCCCHHEEHEEECCCCCCCC
PGATVDADGSVVDVITTGRHDPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPR
CCCEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IPGQVDV
CCCCCCC
>Mature Secondary Structure 
SANSFGKLFTVTTFGESHGPAIGCVVDGCPPGLEIAPEEFTHDLQRRASGKSRHTSARR
CCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
EADEIEILSGVYEGRTTGTPIGLLIRNTDQRSKDYSNIAQQFRPGHADYTYWQKYGIRDP
HHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQLGEIRPAGFDWDAVEDNPFFW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPAGWGEPIYGKLDAELAAALMSINAV
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KGVEIGDGFASAAQRGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRL
CCCCCCCHHHHHHHCCCCCCCCCCCCHHHHCCCCCEEECCCCCCHHEEHEEECCCCCCCC
PGATVDADGSVVDVITTGRHDPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPR
CCCEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IPGQVDV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217