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The map label for this gene is glmM

Identifier: 21243441

GI number: 21243441

Start: 3173619

End: 3174968

Strand: Reverse

Name: glmM

Synonym: XAC2714

Alternate gene names: 21243441

Gene position: 3174968-3173619 (Counterclockwise)

Preceding gene: 21243442

Following gene: 77748669

Centisome position: 61.35

GC content: 67.7

Gene sequence:

>1350_bases
ATGAGCGCACGCAAGTATTTCGGCACCGACGGCATCCGCGGTCGGGTCGGGCAGGGCGTGATCTCGGCCGACTTCGTGCT
GCGCCTGGGCAATGCGCTCGGCCGTGTACTGACCCAGGGCCGCAGCAAGCGGCCGCTGGTGCTGATCGGCAAGGACACCC
GCATTTCCGGCTACATGTTCGAAGCGGCGCTGGAAGCTGGCCTGGTTGCCGCCGGGGCCGACGTGCAGCTGATCGGGCCG
ATGCCGACCCCGGCCATCGCCTTCTTGACCAGCACGCTGCGCGCAGACGCGGGGGTGGTGATCAGCGCCTCGCACAATCC
GCATTACGACAACGGCATCAAGTTCTTCTCCGCCGAAGGCGAGAAGCTCGACGACGCCACCGAAGCGGCGATCGAAGCGG
CGTTGGACGAGCCGTTCCACACGGTGGAATCGGAGCGGTTGGGCAAGGCCATCCGCACGCGTGACGCCATCGGCCGCTAT
ATCGAATTCTGCAAGGCAAGCGTGGCGCGTGGTTTCACCCTGCACGGGCTGAAGATGGTGCTGGATTGCGCGCATGGCGC
CACCTATCACATCGCACCCATGCTGTTCCGCGAGCTGGGTGCCGAGGTGGTGGTCATCGGCGCCGCGCCGGATGGGCTCA
ACATCAACGCCGGCGTGGGCTCGACCCATATCGATAATCTCGCCGCCAAGGTGCGCGAGTGCGGTGCGCACCTGGGTATC
GCCTTCGACGGCGACGGCGACCGCGTGCTGATGGCCGACGACCAGGGCAACCCGGTCGATGGCGACGATCTGCTGTACGT
GCTCGCGCGCTCGTGGCAGGCCAGCGGCCGGCTGACGGGTACCGTGGTCGGCACCTTGATGACCAATTACGGTCTGGAAC
AGGCATTGGCCGCGCTGCACATCCCGTTCCAGCGCGCCAAGGTCGGGGACCGCTACGTGCATCAGGCCCTGGTCGAAGGC
GGCGGCACGTTGGGCGGCGAAACGTCCGGCCATCTGCTGTGCCTGGACCGTGCCAGCACCGGCGATGGCATCGTCAGTGC
GCTGCAGGTGCTCGAAGCGCTGGGTCGCGATAGGCAGAGCCTGCGCGACGCGCTGACGAGCCTAAGCAAGGTGCCGCAGA
AGACCGTCAACGTGCGCCTGGATGGTGGCGCCGCCAAGGCCATTGTGGAAGCGGCCAACGTGCAACAGGCGTTGCAACAG
GCGCAGGCCGCCGTACGAGGCCGTGGCCGCGCGTTCCTGCGCCCGTCGGGCACCGAGCCGGTGGTGCGGGTGACCGTGGA
AGCCGACGACGCCGGCCTGATGCAGGACACGCTCGACCGGCTCTCGGGTGCAGTGCGTGACGCGGCGTGA

Upstream 100 bases:

>100_bases
CCATCGACCAGATCTGCGACCGCCGCCAGATGCGCGACCGCATCGCCGAGCTCACCGCGATGATGATGCGTCAGCCGCAT
CCGCAAGACGCCGACGCCGC

Downstream 100 bases:

>100_bases
GTCGATCGTCATTGGCATCTGCGTGGTCATCGCCAAGGCCGCGACGTTTTACCTGTTGTATCGCCTGCTGATCTGACCCG
CAGGTTTCTCTCGACCCTTT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSARKYFGTDGIRGRVGQGVISADFVLRLGNALGRVLTQGRSKRPLVLIGKDTRISGYMFEAALEAGLVAAGADVQLIGP
MPTPAIAFLTSTLRADAGVVISASHNPHYDNGIKFFSAEGEKLDDATEAAIEAALDEPFHTVESERLGKAIRTRDAIGRY
IEFCKASVARGFTLHGLKMVLDCAHGATYHIAPMLFRELGAEVVVIGAAPDGLNINAGVGSTHIDNLAAKVRECGAHLGI
AFDGDGDRVLMADDQGNPVDGDDLLYVLARSWQASGRLTGTVVGTLMTNYGLEQALAALHIPFQRAKVGDRYVHQALVEG
GGTLGGETSGHLLCLDRASTGDGIVSALQVLEALGRDRQSLRDALTSLSKVPQKTVNVRLDGGAAKAIVEAANVQQALQQ
AQAAVRGRGRAFLRPSGTEPVVRVTVEADDAGLMQDTLDRLSGAVRDAA

Sequences:

>Translated_449_residues
MSARKYFGTDGIRGRVGQGVISADFVLRLGNALGRVLTQGRSKRPLVLIGKDTRISGYMFEAALEAGLVAAGADVQLIGP
MPTPAIAFLTSTLRADAGVVISASHNPHYDNGIKFFSAEGEKLDDATEAAIEAALDEPFHTVESERLGKAIRTRDAIGRY
IEFCKASVARGFTLHGLKMVLDCAHGATYHIAPMLFRELGAEVVVIGAAPDGLNINAGVGSTHIDNLAAKVRECGAHLGI
AFDGDGDRVLMADDQGNPVDGDDLLYVLARSWQASGRLTGTVVGTLMTNYGLEQALAALHIPFQRAKVGDRYVHQALVEG
GGTLGGETSGHLLCLDRASTGDGIVSALQVLEALGRDRQSLRDALTSLSKVPQKTVNVRLDGGAAKAIVEAANVQQALQQ
AQAAVRGRGRAFLRPSGTEPVVRVTVEADDAGLMQDTLDRLSGAVRDAA
>Mature_448_residues
SARKYFGTDGIRGRVGQGVISADFVLRLGNALGRVLTQGRSKRPLVLIGKDTRISGYMFEAALEAGLVAAGADVQLIGPM
PTPAIAFLTSTLRADAGVVISASHNPHYDNGIKFFSAEGEKLDDATEAAIEAALDEPFHTVESERLGKAIRTRDAIGRYI
EFCKASVARGFTLHGLKMVLDCAHGATYHIAPMLFRELGAEVVVIGAAPDGLNINAGVGSTHIDNLAAKVRECGAHLGIA
FDGDGDRVLMADDQGNPVDGDDLLYVLARSWQASGRLTGTVVGTLMTNYGLEQALAALHIPFQRAKVGDRYVHQALVEGG
GTLGGETSGHLLCLDRASTGDGIVSALQVLEALGRDRQSLRDALTSLSKVPQKTVNVRLDGGAAKAIVEAANVQQALQQA
QAAVRGRGRAFLRPSGTEPVVRVTVEADDAGLMQDTLDRLSGAVRDAA

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=55.6053811659193, Blast_Score=466, Evalue=1e-132,
Organism=Escherichia coli, GI1788361, Length=463, Percent_Identity=28.5097192224622, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_XANAC (Q8PJ31)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_643023.1
- ProteinModelPortal:   Q8PJ31
- SMR:   Q8PJ31
- GeneID:   1156785
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2714
- NMPDR:   fig|190486.1.peg.2667
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK10887
- BioCyc:   XAXO190486:XAC2714-MONOMER
- BRENDA:   5.4.2.10
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 47209; Mature: 47078

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARKYFGTDGIRGRVGQGVISADFVLRLGNALGRVLTQGRSKRPLVLIGKDTRISGYMF
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHH
EAALEAGLVAAGADVQLIGPMPTPAIAFLTSTLRADAGVVISASHNPHYDNGIKFFSAEG
HHHHHCCEEECCCCEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCC
EKLDDATEAAIEAALDEPFHTVESERLGKAIRTRDAIGRYIEFCKASVARGFTLHGLKMV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LDCAHGATYHIAPMLFRELGAEVVVIGAAPDGLNINAGVGSTHIDNLAAKVRECGAHLGI
HHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEE
AFDGDGDRVLMADDQGNPVDGDDLLYVLARSWQASGRLTGTVVGTLMTNYGLEQALAALH
EECCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHH
IPFQRAKVGDRYVHQALVEGGGTLGGETSGHLLCLDRASTGDGIVSALQVLEALGRDRQS
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHH
LRDALTSLSKVPQKTVNVRLDGGAAKAIVEAANVQQALQQAQAAVRGRGRAFLRPSGTEP
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
VVRVTVEADDAGLMQDTLDRLSGAVRDAA
EEEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SARKYFGTDGIRGRVGQGVISADFVLRLGNALGRVLTQGRSKRPLVLIGKDTRISGYMF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHH
EAALEAGLVAAGADVQLIGPMPTPAIAFLTSTLRADAGVVISASHNPHYDNGIKFFSAEG
HHHHHCCEEECCCCEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCC
EKLDDATEAAIEAALDEPFHTVESERLGKAIRTRDAIGRYIEFCKASVARGFTLHGLKMV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LDCAHGATYHIAPMLFRELGAEVVVIGAAPDGLNINAGVGSTHIDNLAAKVRECGAHLGI
HHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEE
AFDGDGDRVLMADDQGNPVDGDDLLYVLARSWQASGRLTGTVVGTLMTNYGLEQALAALH
EECCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHH
IPFQRAKVGDRYVHQALVEGGGTLGGETSGHLLCLDRASTGDGIVSALQVLEALGRDRQS
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHH
LRDALTSLSKVPQKTVNVRLDGGAAKAIVEAANVQQALQQAQAAVRGRGRAFLRPSGTEP
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
VVRVTVEADDAGLMQDTLDRLSGAVRDAA
EEEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217