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The map label for this gene is corA [H]

Identifier: 21243201

GI number: 21243201

Start: 2872239

End: 2873255

Strand: Direct

Name: corA [H]

Synonym: XAC2468

Alternate gene names: 21243201

Gene position: 2872239-2873255 (Clockwise)

Preceding gene: 21243200

Following gene: 21243213

Centisome position: 55.5

GC content: 63.13

Gene sequence:

>1017_bases
TTGAAGGATGCGCTCATGAACAGCCAAGGCCATCATCCCGATAATCCGTCCTGCGTCATCACGTGCGCTTACTACGACGG
CGAAGGCAAGCGCCACGACATCAGCCTGGAGCACATCAGCGATGTGCTCCAGCAGCCGGATGGCTTCGTCTGGGTGGGGC
TGTACGAGCCGCAGGAATCGGTGCTGCGCAAGTTGCAGGACGAATTCGGCCTGCACGATCTGGCGATCGAAGACGCGCTC
AAGGCGCATCAACGCCCCAAGGCCGAGAGTTACGGCAACTCGCTGTTCGTGGTGGTCAACACGGCGCAGCTGGTCAACGA
ACGCATCCGCTATGGCGAAACGCATGCCTTCCTGGGAAGGCGCTTCCTGTTGACGGTGCGGCATGGCGCGTCGCTGTCGT
ACGCGCCGGTGCGGCATCGGGTCGAGCGCGAGCCGGCGATGCTGCACATGGGCGCGTCGTTCTGCCTGTACGGCGTGCTC
GATTTCGTGGTCGACAATTACCTGCCGATCATGGACGAGTTCCGCGACACGCTGGAACGCCTGGAAAAAGACATCTTCGC
CGACGACTACAAGCGCGAGACGGTGGTGCGCCTGTATGAGCTCAAGCGCGAACTCAACAAGATGCGGTTGGTGGTGGCGC
CACTGCAGGACGTGCTCTCGCACCTCAAGCGCAACCCCGGCTCACTGATCCACGAAGAAGTCGGCATCTACCTGCGCGAC
GTGCTCGATCACGCGGTGCGCACCAGCGATGCCATCGACACCCTGCGCGAAATGCTGGGCACGGCGCTCAGCGTCAACCT
ATCGATGGTGACGCTGGCCCAGGGCGAAACCGTCAAGCGCCTCGGCGCCTGGGCCGCCCTGCTGGCCGCCCCTACCTTGA
TCACCAGCTGGTACGGCATGAACTTCGCCCACATGCCCGAACTCGATGCCCGCTACGCCTACCCATTGCTGGTCGCCGGC
GTCGTGGGCTCGTGCCTGGTGCTGTATCGCCTGTTCAAGCGCGCCAAGTGGCTGTAG

Upstream 100 bases:

>100_bases
GGCGCAGGACAACCTGCAATGGGTGATGCTGCTGCTGCCGATCCACACCGCACTTGCCATTGCCCTGCGACTGCGTGACC
TGCCCGTCCGTACGCGCTGA

Downstream 100 bases:

>100_bases
GGCCGCGTTGCGGCCAGGGATTGTGGAATCGAGAATCGTAAGAGCGGTTTCCTTCATCTCCCAGATGTAGGCGGAACGGA
GAAAGTGCGGTTGTGCATTC

Product: magnesium and cobalt transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKDALMNSQGHHPDNPSCVITCAYYDGEGKRHDISLEHISDVLQQPDGFVWVGLYEPQESVLRKLQDEFGLHDLAIEDAL
KAHQRPKAESYGNSLFVVVNTAQLVNERIRYGETHAFLGRRFLLTVRHGASLSYAPVRHRVEREPAMLHMGASFCLYGVL
DFVVDNYLPIMDEFRDTLERLEKDIFADDYKRETVVRLYELKRELNKMRLVVAPLQDVLSHLKRNPGSLIHEEVGIYLRD
VLDHAVRTSDAIDTLREMLGTALSVNLSMVTLAQGETVKRLGAWAALLAAPTLITSWYGMNFAHMPELDARYAYPLLVAG
VVGSCLVLYRLFKRAKWL

Sequences:

>Translated_338_residues
MKDALMNSQGHHPDNPSCVITCAYYDGEGKRHDISLEHISDVLQQPDGFVWVGLYEPQESVLRKLQDEFGLHDLAIEDAL
KAHQRPKAESYGNSLFVVVNTAQLVNERIRYGETHAFLGRRFLLTVRHGASLSYAPVRHRVEREPAMLHMGASFCLYGVL
DFVVDNYLPIMDEFRDTLERLEKDIFADDYKRETVVRLYELKRELNKMRLVVAPLQDVLSHLKRNPGSLIHEEVGIYLRD
VLDHAVRTSDAIDTLREMLGTALSVNLSMVTLAQGETVKRLGAWAALLAAPTLITSWYGMNFAHMPELDARYAYPLLVAG
VVGSCLVLYRLFKRAKWL
>Mature_338_residues
MKDALMNSQGHHPDNPSCVITCAYYDGEGKRHDISLEHISDVLQQPDGFVWVGLYEPQESVLRKLQDEFGLHDLAIEDAL
KAHQRPKAESYGNSLFVVVNTAQLVNERIRYGETHAFLGRRFLLTVRHGASLSYAPVRHRVEREPAMLHMGASFCLYGVL
DFVVDNYLPIMDEFRDTLERLEKDIFADDYKRETVVRLYELKRELNKMRLVVAPLQDVLSHLKRNPGSLIHEEVGIYLRD
VLDHAVRTSDAIDTLREMLGTALSVNLSMVTLAQGETVKRLGAWAALLAAPTLITSWYGMNFAHMPELDARYAYPLLVAG
VVGSCLVLYRLFKRAKWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 38438; Mature: 38438

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDALMNSQGHHPDNPSCVITCAYYDGEGKRHDISLEHISDVLQQPDGFVWVGLYEPQES
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCHHH
VLRKLQDEFGLHDLAIEDALKAHQRPKAESYGNSLFVVVNTAQLVNERIRYGETHAFLGR
HHHHHHHHHCCHHHHHHHHHHHHCCCCHHHCCCEEEEEEECHHHHHHHHHHCCHHHHHHH
RFLLTVRHGASLSYAPVRHRVEREPAMLHMGASFCLYGVLDFVVDNYLPIMDEFRDTLER
HHEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LEKDIFADDYKRETVVRLYELKRELNKMRLVVAPLQDVLSHLKRNPGSLIHEEVGIYLRD
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VLDHAVRTSDAIDTLREMLGTALSVNLSMVTLAQGETVKRLGAWAALLAAPTLITSWYGM
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
NFAHMPELDARYAYPLLVAGVVGSCLVLYRLFKRAKWL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKDALMNSQGHHPDNPSCVITCAYYDGEGKRHDISLEHISDVLQQPDGFVWVGLYEPQES
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCHHH
VLRKLQDEFGLHDLAIEDALKAHQRPKAESYGNSLFVVVNTAQLVNERIRYGETHAFLGR
HHHHHHHHHCCHHHHHHHHHHHHCCCCHHHCCCEEEEEEECHHHHHHHHHHCCHHHHHHH
RFLLTVRHGASLSYAPVRHRVEREPAMLHMGASFCLYGVLDFVVDNYLPIMDEFRDTLER
HHEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LEKDIFADDYKRETVVRLYELKRELNKMRLVVAPLQDVLSHLKRNPGSLIHEEVGIYLRD
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VLDHAVRTSDAIDTLREMLGTALSVNLSMVTLAQGETVKRLGAWAALLAAPTLITSWYGM
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
NFAHMPELDARYAYPLLVAGVVGSCLVLYRLFKRAKWL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]