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The map label for this gene is pglA [H]

Identifier: 21243108

GI number: 21243108

Start: 2767248

End: 2768918

Strand: Direct

Name: pglA [H]

Synonym: XAC2374

Alternate gene names: 21243108

Gene position: 2767248-2768918 (Clockwise)

Preceding gene: 21243107

Following gene: 21243115

Centisome position: 53.47

GC content: 64.45

Gene sequence:

>1671_bases
ATGCCGTACCATCGCCTTGTTCCCGCCGTCGCGCCACTGCCCCTTGCCCTGCTCGGCCTGTCCACGTTTCACGCCAGCGC
GGCGCTACCGCACGGGCAGGATGCACCCGATACCGCGCACAGCATTTCCACCAGCTGGGGGGAGATCCAGCAGCCAGCAT
TGCCGACCAAGGTATGCGCCACGCTCAAGGCTGCGCTGACCCCGGTGGGTGGTTCAGTGGATATGCTCGACCAGAACCCT
GCCCACTCCAAGCGCGATACCGCGCGCCTGCAGGCGGCCATCGACGATTGCCCTGCCGGCAGCGCGGTGCGTCTTGCCCC
CGGCGATGCCGGCGAATCCGGCGTGCTCAGTGGGCCGCTGACCATCAAGAGCGGGGTCACGCTATGGATCGACCGCGGCG
TCACCTTGTTCGGCTCGCGCAATCCGCAGGACTACGACAACGGCCTGGGCACCTGCGGCACCGCCACCAGCGACAAAGCC
AAGTCGTGTCGTCCGCTGATCCATCTCTCCGACACGGCCAACAGCGCCATCGTCGGCGCCGGCAAGATCGACGGCCGTGG
CGGCAGCACGCTCACTGCCGGGCCCAATGCCGGCAAGGCCAGCTGGTGGGATCTTGCCTATCTCAACGTCACCAAGGGCT
TGAGCCAGCACGTGCCGCGCCTGTTGCAGATCGACGACAGCGCCGACGTCACCTTGTACGACATCACCCTGGAGAACTCG
CCCAATTTCCATGTCATCAGCGACAACGTGGTGGGCCTGACCGCGTGGGGCATCAAGATTCTGGCGCCCAGCCTGGTCTA
TTCGCGTCCCGGCTACCGATGCCCGGCAGGCAGCACCCCGGACGTCAATCCGCACGCGACCTGCTTCACGCCGGAGACTG
CCAAGAACACCGACGGCTTCGACCCGGGCCAGTCGAAGAATGTGCTGCTGGCTTACTCGTACATCGGCACCGGCGATGAC
GGTGTGGCGATCAAGGCGCACGCCAACAGCAAGCGCAGTATCGCCTCGGAAAACATGCTGTTCGCCTACAACCAGTTCTA
CTACACCCATGGCTTTTCGCTGGGCAGCGAAACCGATTCGGGCATGCGCCATATCGCCGTGCGCGGCTTGAGCATTGACG
GCTTCAACGCCAACGATGTGCAGCGCGATCCCTACTCGGCCAATGGCCTCCGCATCAAGTCCGACGCCTCCCGCGGCGGC
CAGGTCTACGACATCAGCTTCGAGAACATCTGCATGCGCGGGGTTGCGCGGCCACTGGTGTTCGATGCCAACTACGCCAA
TCCCGCCACCCGCGCCGCGCCGCCGCAGTTCAACGGCATTTCGCTCAGTCACGTGCATTCGCTGGGTTCGACCACCCTGG
GTGGCGGCGAACTGAGTTTCTATGGGTATCGCGATGCCGGCACCACCCGGCCAATCACCATCTCGCTGGACAATGTCGTG
CTGGAAGGCGGCAAGGTGAGCTTCGCGCAGCCGCATTTCGGCGGGCCCGCGAGCAACCCGGGCGCGACGCACTTCACCTT
CAAGGGTGGCCCGGTGAGCTTTTACGATCAGCTGACCGAATCGGTGCCCAACGATGTGCAGCTACAGGGCAAACCCGGCC
CGGGCACGCCACTGCAATGCAATGACGCCTTCATTGCCTATCACTCGGTACTGCCGGATTCGCCGATTTGA

Upstream 100 bases:

>100_bases
ACGCATGTGGCAGGGCACCGATGTTCGCAGCGCCTCATACAGGTGCATCTCGCTGCGCTCGTTTATCTGGCGCGCCTGTC
GCATAACCGGAGAAAGACCT

Downstream 100 bases:

>100_bases
ATCCAACGTGCTGAGCGCTAAGGAAATCACATGCGATGCAACGCTTGCTGCAATCTGCCGGTCGCAGCAAGCCATCGGTC
CAAACCCAACAATGCAACGG

Product: polygalacturonase

Products: NA

Alternate protein names: PGA; Pectinase [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MPYHRLVPAVAPLPLALLGLSTFHASAALPHGQDAPDTAHSISTSWGEIQQPALPTKVCATLKAALTPVGGSVDMLDQNP
AHSKRDTARLQAAIDDCPAGSAVRLAPGDAGESGVLSGPLTIKSGVTLWIDRGVTLFGSRNPQDYDNGLGTCGTATSDKA
KSCRPLIHLSDTANSAIVGAGKIDGRGGSTLTAGPNAGKASWWDLAYLNVTKGLSQHVPRLLQIDDSADVTLYDITLENS
PNFHVISDNVVGLTAWGIKILAPSLVYSRPGYRCPAGSTPDVNPHATCFTPETAKNTDGFDPGQSKNVLLAYSYIGTGDD
GVAIKAHANSKRSIASENMLFAYNQFYYTHGFSLGSETDSGMRHIAVRGLSIDGFNANDVQRDPYSANGLRIKSDASRGG
QVYDISFENICMRGVARPLVFDANYANPATRAAPPQFNGISLSHVHSLGSTTLGGGELSFYGYRDAGTTRPITISLDNVV
LEGGKVSFAQPHFGGPASNPGATHFTFKGGPVSFYDQLTESVPNDVQLQGKPGPGTPLQCNDAFIAYHSVLPDSPI

Sequences:

>Translated_556_residues
MPYHRLVPAVAPLPLALLGLSTFHASAALPHGQDAPDTAHSISTSWGEIQQPALPTKVCATLKAALTPVGGSVDMLDQNP
AHSKRDTARLQAAIDDCPAGSAVRLAPGDAGESGVLSGPLTIKSGVTLWIDRGVTLFGSRNPQDYDNGLGTCGTATSDKA
KSCRPLIHLSDTANSAIVGAGKIDGRGGSTLTAGPNAGKASWWDLAYLNVTKGLSQHVPRLLQIDDSADVTLYDITLENS
PNFHVISDNVVGLTAWGIKILAPSLVYSRPGYRCPAGSTPDVNPHATCFTPETAKNTDGFDPGQSKNVLLAYSYIGTGDD
GVAIKAHANSKRSIASENMLFAYNQFYYTHGFSLGSETDSGMRHIAVRGLSIDGFNANDVQRDPYSANGLRIKSDASRGG
QVYDISFENICMRGVARPLVFDANYANPATRAAPPQFNGISLSHVHSLGSTTLGGGELSFYGYRDAGTTRPITISLDNVV
LEGGKVSFAQPHFGGPASNPGATHFTFKGGPVSFYDQLTESVPNDVQLQGKPGPGTPLQCNDAFIAYHSVLPDSPI
>Mature_555_residues
PYHRLVPAVAPLPLALLGLSTFHASAALPHGQDAPDTAHSISTSWGEIQQPALPTKVCATLKAALTPVGGSVDMLDQNPA
HSKRDTARLQAAIDDCPAGSAVRLAPGDAGESGVLSGPLTIKSGVTLWIDRGVTLFGSRNPQDYDNGLGTCGTATSDKAK
SCRPLIHLSDTANSAIVGAGKIDGRGGSTLTAGPNAGKASWWDLAYLNVTKGLSQHVPRLLQIDDSADVTLYDITLENSP
NFHVISDNVVGLTAWGIKILAPSLVYSRPGYRCPAGSTPDVNPHATCFTPETAKNTDGFDPGQSKNVLLAYSYIGTGDDG
VAIKAHANSKRSIASENMLFAYNQFYYTHGFSLGSETDSGMRHIAVRGLSIDGFNANDVQRDPYSANGLRIKSDASRGGQ
VYDISFENICMRGVARPLVFDANYANPATRAAPPQFNGISLSHVHSLGSTTLGGGELSFYGYRDAGTTRPITISLDNVVL
EGGKVSFAQPHFGGPASNPGATHFTFKGGPVSFYDQLTESVPNDVQLQGKPGPGTPLQCNDAFIAYHSVLPDSPI

Specific function: Contributes to the wilt disease production on tomato [H]

COG id: COG5434

COG function: function code M; Endopolygalacturonase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 28 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000743
- InterPro:   IPR012334
- InterPro:   IPR011050 [H]

Pfam domain/function: PF00295 Glyco_hydro_28 [H]

EC number: =3.2.1.15 [H]

Molecular weight: Translated: 58417; Mature: 58286

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYHRLVPAVAPLPLALLGLSTFHASAALPHGQDAPDTAHSISTSWGEIQQPALPTKVCA
CCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHCCCCCCCHHHHH
TLKAALTPVGGSVDMLDQNPAHSKRDTARLQAAIDDCPAGSAVRLAPGDAGESGVLSGPL
HHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCE
TIKSGVTLWIDRGVTLFGSRNPQDYDNGLGTCGTATSDKAKSCRPLIHLSDTANSAIVGA
EECCCEEEEEECCEEEECCCCCCHHHCCCCCCCCCCCCCHHCCCCEEEECCCCCCEEEEC
GKIDGRGGSTLTAGPNAGKASWWDLAYLNVTKGLSQHVPRLLQIDDSADVTLYDITLENS
CEECCCCCCEEECCCCCCCCCEEEEEEEEHHHHHHHHCCCEEEECCCCCEEEEEEEECCC
PNFHVISDNVVGLTAWGIKILAPSLVYSRPGYRCPAGSTPDVNPHATCFTPETAKNTDGF
CCEEEEECCEEEEEECCHHHHCCHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCC
DPGQSKNVLLAYSYIGTGDDGVAIKAHANSKRSIASENMLFAYNQFYYTHGFSLGSETDS
CCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCC
GMRHIAVRGLSIDGFNANDVQRDPYSANGLRIKSDASRGGQVYDISFENICMRGVARPLV
CCEEEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECHHHHHHHHCCCCEE
FDANYANPATRAAPPQFNGISLSHVHSLGSTTLGGGELSFYGYRDAGTTRPITISLDNVV
EECCCCCCCCCCCCCCCCCEEHHHHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEECCEE
LEGGKVSFAQPHFGGPASNPGATHFTFKGGPVSFYDQLTESVPNDVQLQGKPGPGTPLQC
EECCEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEE
NDAFIAYHSVLPDSPI
CCEEEEEEECCCCCCC
>Mature Secondary Structure 
PYHRLVPAVAPLPLALLGLSTFHASAALPHGQDAPDTAHSISTSWGEIQQPALPTKVCA
CHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHCCCCCCCHHHHH
TLKAALTPVGGSVDMLDQNPAHSKRDTARLQAAIDDCPAGSAVRLAPGDAGESGVLSGPL
HHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCE
TIKSGVTLWIDRGVTLFGSRNPQDYDNGLGTCGTATSDKAKSCRPLIHLSDTANSAIVGA
EECCCEEEEEECCEEEECCCCCCHHHCCCCCCCCCCCCCHHCCCCEEEECCCCCCEEEEC
GKIDGRGGSTLTAGPNAGKASWWDLAYLNVTKGLSQHVPRLLQIDDSADVTLYDITLENS
CEECCCCCCEEECCCCCCCCCEEEEEEEEHHHHHHHHCCCEEEECCCCCEEEEEEEECCC
PNFHVISDNVVGLTAWGIKILAPSLVYSRPGYRCPAGSTPDVNPHATCFTPETAKNTDGF
CCEEEEECCEEEEEECCHHHHCCHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCC
DPGQSKNVLLAYSYIGTGDDGVAIKAHANSKRSIASENMLFAYNQFYYTHGFSLGSETDS
CCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCC
GMRHIAVRGLSIDGFNANDVQRDPYSANGLRIKSDASRGGQVYDISFENICMRGVARPLV
CCEEEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECHHHHHHHHCCCCEE
FDANYANPATRAAPPQFNGISLSHVHSLGSTTLGGGELSFYGYRDAGTTRPITISLDNVV
EECCCCCCCCCCCCCCCCCEEHHHHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEECCEE
LEGGKVSFAQPHFGGPASNPGATHFTFKGGPVSFYDQLTESVPNDVQLQGKPGPGTPLQC
EECCEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEE
NDAFIAYHSVLPDSPI
CCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2193922 [H]