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The map label for this gene is eutP [C]

Identifier: 21243098

GI number: 21243098

Start: 2757530

End: 2758894

Strand: Direct

Name: eutP [C]

Synonym: XAC2364

Alternate gene names: 21243098

Gene position: 2757530-2758894 (Clockwise)

Preceding gene: 21243097

Following gene: 21243099

Centisome position: 53.28

GC content: 64.69

Gene sequence:

>1365_bases
ATGTGCGACATGCGCAACGAGCACCTCAAACCGACCCTGGGCACCTGGCAGCTGTGGGGCATCGCGGTGGGGCTGGTGAT
TTCAGGCGAGTATTTCGGCTGGAGTTACGGCTGGGGCACCGCCGGTACGCTCGGGTTTCTGGCGACCACGCTGCTGGTCG
CCGTGATGTACACCTGCTTCATCTTCAGCTTCACCGAATTGACCACCGCCATTCCCAATGCGGGCGGGCCCTTCGCCTAC
AGCCTGCGCGCGTTCGGCACCTATGGCGGCATGCTGGCGGGCCTGGCCACGTTGATCGAATTCGTCTTCGCGCCGCCGGC
CATCGCGATGGCGATCGGCGCGTATCTGAATGTGCAGTACCCCATGCTCGATCCGCGCATCGCAGCGATTGGCGCCTACC
TGGTCTTCATGAGCTTGAACATCGTGGGCGTGGCGATTGCAGCGACCTTCGAGCTGATCGTGACCTTGCTGGCGGTGATC
GAGTTGCTGGTGTTCATGGGTGTGGTGGCGCCGGGTTTCAGCGTGGCGCGCTTCGCCGCCAACGGCTGGGCCGGCAGCGA
CGTGTTCGGGCCGGCGGCCATTTCCGGAATCTTCGCCGCGATTCCGTTTGCGATCTGGTTTTTCCTGGCGATCGAAGGGG
CAGCGATGGCGGCCGAAGAAGCCAAAGACCCCACGCGCACGATTCCGCGCGCCTACATCGCCGGCATTCTCACCCTGGTG
ATCTTGGCGCTGGGGGTGATGGTGTTTGCCGGCGGCGTCGGCGACTGGCGCCAGCTGTCCAACATCAACGACCCGCTGCC
GCAGGCGATGAAGGCGGTGGTCGGCAACAGTTCCAGCTGGTTGCACATGCTGGTGTGGATCGGCCTGTTCGGGCTGGTGG
CGAGTTTCCACGGCATCATCCTGGGCTATTCGCGGCAGTTCTTCGCGCTGGCGCGTGCCGGCTTCCTGCCGCATGGGCTG
GCCAGGCTGTCGCGTTTTCGCACGCCGCATCGCGCCATTCTGGCCGGCGGCGTCATCGGCATTGCGGCAATCTGCAGCGA
CAGCGTGGTCAAGATCCAGGGCATGTCGTTGACCGCAGCGATGATCACCATGTCGGTGTTCGGGGCGATCGTGATGTATG
TGATGAGCATGCTCAGCCTGTTCAAGCTGCGTCGCGCCGAACCGGGGTTGGAGCGTAGTTTCCGCGCACCGGGGTACCCG
GTGGTGCCGGCCATTGCGCTGCTGCTGGCGCTGGTGTGCCTGGTGGCGATGGTGTGGTTCAACCCGATTGTGGCGTTGAT
CTTTCTGGGCCTGCTGCTGTTGGGCGCGGCGTGTTGCGTCCTTAGCCTGCGCACCCAGCACACGCCCGCGGCCCGCGCCG
GATGA

Upstream 100 bases:

>100_bases
ACCGTCGCGCGTCGCTGCAGCTGAACGCTTGAGTTGCTGACGGTCGGTCCGTCGCTTCGGCGTCGGGCGTGCTTCATCTC
CCCTCCCCCGACTGCAGGAG

Downstream 100 bases:

>100_bases
GCGGCTTTGCCTTCACCGCAGGCGGCGAGCGTTTTCGGTTTGCCGATCTGAAGCAGCTGCTGGCCAAGGCGACGCCGGCA
CGCTCCGGCGACCAGCTGGC

Product: ethanolamin permease

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MCDMRNEHLKPTLGTWQLWGIAVGLVISGEYFGWSYGWGTAGTLGFLATTLLVAVMYTCFIFSFTELTTAIPNAGGPFAY
SLRAFGTYGGMLAGLATLIEFVFAPPAIAMAIGAYLNVQYPMLDPRIAAIGAYLVFMSLNIVGVAIAATFELIVTLLAVI
ELLVFMGVVAPGFSVARFAANGWAGSDVFGPAAISGIFAAIPFAIWFFLAIEGAAMAAEEAKDPTRTIPRAYIAGILTLV
ILALGVMVFAGGVGDWRQLSNINDPLPQAMKAVVGNSSSWLHMLVWIGLFGLVASFHGIILGYSRQFFALARAGFLPHGL
ARLSRFRTPHRAILAGGVIGIAAICSDSVVKIQGMSLTAAMITMSVFGAIVMYVMSMLSLFKLRRAEPGLERSFRAPGYP
VVPAIALLLALVCLVAMVWFNPIVALIFLGLLLLGAACCVLSLRTQHTPAARAG

Sequences:

>Translated_454_residues
MCDMRNEHLKPTLGTWQLWGIAVGLVISGEYFGWSYGWGTAGTLGFLATTLLVAVMYTCFIFSFTELTTAIPNAGGPFAY
SLRAFGTYGGMLAGLATLIEFVFAPPAIAMAIGAYLNVQYPMLDPRIAAIGAYLVFMSLNIVGVAIAATFELIVTLLAVI
ELLVFMGVVAPGFSVARFAANGWAGSDVFGPAAISGIFAAIPFAIWFFLAIEGAAMAAEEAKDPTRTIPRAYIAGILTLV
ILALGVMVFAGGVGDWRQLSNINDPLPQAMKAVVGNSSSWLHMLVWIGLFGLVASFHGIILGYSRQFFALARAGFLPHGL
ARLSRFRTPHRAILAGGVIGIAAICSDSVVKIQGMSLTAAMITMSVFGAIVMYVMSMLSLFKLRRAEPGLERSFRAPGYP
VVPAIALLLALVCLVAMVWFNPIVALIFLGLLLLGAACCVLSLRTQHTPAARAG
>Mature_454_residues
MCDMRNEHLKPTLGTWQLWGIAVGLVISGEYFGWSYGWGTAGTLGFLATTLLVAVMYTCFIFSFTELTTAIPNAGGPFAY
SLRAFGTYGGMLAGLATLIEFVFAPPAIAMAIGAYLNVQYPMLDPRIAAIGAYLVFMSLNIVGVAIAATFELIVTLLAVI
ELLVFMGVVAPGFSVARFAANGWAGSDVFGPAAISGIFAAIPFAIWFFLAIEGAAMAAEEAKDPTRTIPRAYIAGILTLV
ILALGVMVFAGGVGDWRQLSNINDPLPQAMKAVVGNSSSWLHMLVWIGLFGLVASFHGIILGYSRQFFALARAGFLPHGL
ARLSRFRTPHRAILAGGVIGIAAICSDSVVKIQGMSLTAAMITMSVFGAIVMYVMSMLSLFKLRRAEPGLERSFRAPGYP
VVPAIALLLALVCLVAMVWFNPIVALIFLGLLLLGAACCVLSLRTQHTPAARAG

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786302, Length=370, Percent_Identity=22.1621621621622, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786789, Length=390, Percent_Identity=20.5128205128205, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790653, Length=364, Percent_Identity=25, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081708, Length=440, Percent_Identity=22.9545454545455, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081869, Length=453, Percent_Identity=20.3090507726269, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082250, Length=436, Percent_Identity=22.4770642201835, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786602, Length=368, Percent_Identity=19.5652173913043, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48164; Mature: 48164

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]