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The map label for this gene is cycJ

Identifier: 21243062

GI number: 21243062

Start: 2720070

End: 2720540

Strand: Direct

Name: cycJ

Synonym: XAC2327

Alternate gene names: 21243062

Gene position: 2720070-2720540 (Clockwise)

Preceding gene: 21243061

Following gene: 21243063

Centisome position: 52.56

GC content: 65.39

Gene sequence:

>471_bases
GTGAACCCGCAACGTCGCCGCCGCCTGTGGCTGGTGCTGGCGTTGGTACTGGCCGGCGGGCTGGCAACCACGCTGGTGGC
GATGGCCTTGCAGCGCAACGTGGCCTATCTGTACACGCCATCGGAAGTGCTGCGCGGCGACGCCGGCGCGCATTCCCGCT
TCCGGCTCGGCGGCATGGTCGAAAAAGGCTCGTTCAAACGCGCCTCTGGCTCCTTGGAAGCGCAATTCCGCGTCACCGAT
GGCGATGCGCAATTGTCCGTCAGTTACGACCGCATCCTGCCGGACCTGTTTCGCGAGGGGCAGGCAGTGGTGGCCACTGG
CCGCATGCAGCACGGCATCTTCGTCGCCGAAGATGTGCTGGCCAAGCACGACGAAACCTATATGCCGAAGGAAGTGGCCG
ACAAGATGGGCAGCGCGCACCGCAAGCACGATGTGCCAGCCGCGGCCGGTCAAGTTGGAGAGCGGCAGTGA

Upstream 100 bases:

>100_bases
TCGCCGGCCGTTGGCAGGTGCGTCGCGCACTGAAAACCGCCCAGGCGCGCCGCCTGCGCGAGCGCAAGCGCGCGGTGCCC
GGCGATGCGGAGCTGATCCG

Downstream 100 bases:

>100_bases
TGCCGTGCATCGGGACATCGGCATGCCGGCCGGCAGGTGGCTTGCGCGGTGCGTACGCAGCTAATGATGTCACCGCGCGT
GGGCAAGCAGGTGCAACTGC

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E 2; Heme chaperone CcmE 2

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MNPQRRRRLWLVLALVLAGGLATTLVAMALQRNVAYLYTPSEVLRGDAGAHSRFRLGGMVEKGSFKRASGSLEAQFRVTD
GDAQLSVSYDRILPDLFREGQAVVATGRMQHGIFVAEDVLAKHDETYMPKEVADKMGSAHRKHDVPAAAGQVGERQ

Sequences:

>Translated_156_residues
MNPQRRRRLWLVLALVLAGGLATTLVAMALQRNVAYLYTPSEVLRGDAGAHSRFRLGGMVEKGSFKRASGSLEAQFRVTD
GDAQLSVSYDRILPDLFREGQAVVATGRMQHGIFVAEDVLAKHDETYMPKEVADKMGSAHRKHDVPAAAGQVGERQ
>Mature_156_residues
MNPQRRRRLWLVLALVLAGGLATTLVAMALQRNVAYLYTPSEVLRGDAGAHSRFRLGGMVEKGSFKRASGSLEAQFRVTD
GDAQLSVSYDRILPDLFREGQAVVATGRMQHGIFVAEDVLAKHDETYMPKEVADKMGSAHRKHDVPAAAGQVGERQ

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=149, Percent_Identity=42.9530201342282, Blast_Score=122, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME2_XANAC (Q8PK49)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642644.1
- ProteinModelPortal:   Q8PK49
- SMR:   Q8PK49
- GeneID:   1156398
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2327
- NMPDR:   fig|190486.1.peg.2288
- HOGENOM:   HBG296631
- OMA:   NTITARP
- ProtClustDB:   PRK13254
- BioCyc:   XAXO190486:XAC2327-MONOMER
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 17090; Mature: 17090

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: BINDING 123-123

Signals:

None

Transmembrane regions:

HASH(0xf460e74)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPQRRRRLWLVLALVLAGGLATTLVAMALQRNVAYLYTPSEVLRGDAGAHSRFRLGGMV
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEECCHHHHCCCCCCCCEEEECCEE
EKGSFKRASGSLEAQFRVTDGDAQLSVSYDRILPDLFREGQAVVATGRMQHGIFVAEDVL
CCCCCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHH
AKHDETYMPKEVADKMGSAHRKHDVPAAAGQVGERQ
HHCCCCCCCHHHHHHHHCHHHHCCCCHHHCCCCCCH
>Mature Secondary Structure
MNPQRRRRLWLVLALVLAGGLATTLVAMALQRNVAYLYTPSEVLRGDAGAHSRFRLGGMV
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEECCHHHHCCCCCCCCEEEECCEE
EKGSFKRASGSLEAQFRVTDGDAQLSVSYDRILPDLFREGQAVVATGRMQHGIFVAEDVL
CCCCCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHH
AKHDETYMPKEVADKMGSAHRKHDVPAAAGQVGERQ
HHCCCCCCCHHHHHHHHCHHHHCCCCHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217