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The map label for this gene is cycZ [H]

Identifier: 21243060

GI number: 21243060

Start: 2719154

End: 2719906

Strand: Direct

Name: cycZ [H]

Synonym: XAC2325

Alternate gene names: 21243060

Gene position: 2719154-2719906 (Clockwise)

Preceding gene: 21243059

Following gene: 21243061

Centisome position: 52.54

GC content: 64.81

Gene sequence:

>753_bases
ATGAACGTCGTCGTCCGCTGGTTCCACCAACTCGCATCGCCCCCGATCTTCGACCGTTTTACTGCGCGCTGGGCGCCGTG
GTGCTACGCGCTGGCCGTGTTGCTGCTGGGCGTGGGCATCTGGCAGGCCTTGTTCGCGGTGCCGGCGGATTACCAGCAAG
GCGACAGCTTCCGTATCCTCTACATCCATGTGCCGAGCGCGTGGATGAGCCTGTTCGTGTTCGGGCTGATGGCGCTGTAT
GCGGCCATCGCGTTGATCTGGCGGATCAAGATCTGCGAGATTCTGGCGATGGCGTGCGCGCCGATCGGCGCTGCATTTAC
CGTGATCACCCTGCTGACCGGCAGCATCTGGGGCAAACCGATGTGGGGCGCCTGGTGGGACTGGGACCCGCGCCTGACCA
CCGAATTGATTCTGCTGTTCCTGTATCTGGGCGTGATCGGCCTGTACCACGCCATCGACGACCGCCGTCAGGCCGCGCGC
GCGGCGGCGTTGCTGGCCATCGTCGGAGTGGCGCTGCTGCCGGTGATCCGCTATTCGGTGGTGTGGTGGAATTCGCTGCA
TCAGGGCCAGAGCATTCGCCTGCTTGGGCCGTCCACGATCGATGCCAGCATGCTGCTGCCGCTGTGGTTGATGGTGATCG
GCACCAAGTTCTGGTTTGTCGGGTCACTGTTGACGCGCGCGCGCGCCGACAACCTGCGCCGCGAGGCCGGCAAGGCCTGG
ATCGTGGGCGATGCGCAGGAGAGTGCGGCATGA

Upstream 100 bases:

>100_bases
AGTTGAGCGCTGCAGTCGTTGCATTGTCGATAGCATGCCCCGCACAACGCGTTGTTGCTGTTTCGAGAGCCAATGCCATT
CCAAAGGCTACTGCCATCGC

Downstream 100 bases:

>100_bases
GCTACCTGCCTTACGTCATCGCCGCCTATGCGGTGTTCGTGCTGGTGCTGCTGTGGGACCTGATCGCCGGCCGTTGGCAG
GTGCGTCGCGCACTGAAAAC

Product: ABC transporter heme permease

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmC [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNVVVRWFHQLASPPIFDRFTARWAPWCYALAVLLLGVGIWQALFAVPADYQQGDSFRILYIHVPSAWMSLFVFGLMALY
AAIALIWRIKICEILAMACAPIGAAFTVITLLTGSIWGKPMWGAWWDWDPRLTTELILLFLYLGVIGLYHAIDDRRQAAR
AAALLAIVGVALLPVIRYSVVWWNSLHQGQSIRLLGPSTIDASMLLPLWLMVIGTKFWFVGSLLTRARADNLRREAGKAW
IVGDAQESAA

Sequences:

>Translated_250_residues
MNVVVRWFHQLASPPIFDRFTARWAPWCYALAVLLLGVGIWQALFAVPADYQQGDSFRILYIHVPSAWMSLFVFGLMALY
AAIALIWRIKICEILAMACAPIGAAFTVITLLTGSIWGKPMWGAWWDWDPRLTTELILLFLYLGVIGLYHAIDDRRQAAR
AAALLAIVGVALLPVIRYSVVWWNSLHQGQSIRLLGPSTIDASMLLPLWLMVIGTKFWFVGSLLTRARADNLRREAGKAW
IVGDAQESAA
>Mature_250_residues
MNVVVRWFHQLASPPIFDRFTARWAPWCYALAVLLLGVGIWQALFAVPADYQQGDSFRILYIHVPSAWMSLFVFGLMALY
AAIALIWRIKICEILAMACAPIGAAFTVITLLTGSIWGKPMWGAWWDWDPRLTTELILLFLYLGVIGLYHAIDDRRQAAR
AAALLAIVGVALLPVIRYSVVWWNSLHQGQSIRLLGPSTIDASMLLPLWLMVIGTKFWFVGSLLTRARADNLRREAGKAW
IVGDAQESAA

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=226, Percent_Identity=51.7699115044248, Blast_Score=208, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 28028; Mature: 28028

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVVVRWFHQLASPPIFDRFTARWAPWCYALAVLLLGVGIWQALFAVPADYQQGDSFRIL
CCHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
YIHVPSAWMSLFVFGLMALYAAIALIWRIKICEILAMACAPIGAAFTVITLLTGSIWGKP
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MWGAWWDWDPRLTTELILLFLYLGVIGLYHAIDDRRQAARAAALLAIVGVALLPVIRYSV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWWNSLHQGQSIRLLGPSTIDASMLLPLWLMVIGTKFWFVGSLLTRARADNLRREAGKAW
HHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
IVGDAQESAA
EEECCHHCCC
>Mature Secondary Structure
MNVVVRWFHQLASPPIFDRFTARWAPWCYALAVLLLGVGIWQALFAVPADYQQGDSFRIL
CCHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
YIHVPSAWMSLFVFGLMALYAAIALIWRIKICEILAMACAPIGAAFTVITLLTGSIWGKP
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MWGAWWDWDPRLTTELILLFLYLGVIGLYHAIDDRRQAARAAALLAIVGVALLPVIRYSV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWWNSLHQGQSIRLLGPSTIDASMLLPLWLMVIGTKFWFVGSLLTRARADNLRREAGKAW
HHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
IVGDAQESAA
EEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]