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The map label for this gene is fhuA [H]

Identifier: 21242920

GI number: 21242920

Start: 2556844

End: 2559024

Strand: Direct

Name: fhuA [H]

Synonym: XAC2185

Alternate gene names: 21242920

Gene position: 2556844-2559024 (Clockwise)

Preceding gene: 21242919

Following gene: 21242921

Centisome position: 49.4

GC content: 68.45

Gene sequence:

>2181_bases
ATGACATACCACCTCCCCCCGCGCCGCTTCCAGCGCCGTGCGCTGCGCACCACGCCCATTGCGGCCATCGTCATGGCCGG
CGCGTTCACCACGCCCAATGCGGCAGCGCAAACGCAGGCCACGGCACCCGCGGCTCCCACGGCCCTGCCCACCGTAACCG
TGACTGAGCACTCTGATCCAACCCAGCGCAGCTCAACCGGGACCAAAACCGACACACCTTTGATCGAGACGCCCCAGTCC
ATCTCCGTGATTCCTGCCGATCGCATGGCAACGCAAGGCGCGACCAACGTGAAAGAAGCGCTCAGCTACTCCCCGGGCGT
GATTCCCACCCGCTTCGGCGCCGACTCGCGCTATGACTGGATCTCGCTGCGCGGCTTCGATGCGTATGCGCCGGGCTTCT
ACCTGGACGGCATGCCGCTGCGCAACAACGGCAACTGGGGCATCTGGCCGATCGAGAGCTACGGCGCCGAGCGCATCGAA
CTGCTGCGCGGCCCGGCATCGGTGCTGTATGGCCAGAGCGGCCCCGGCGGCCTCGTGAACGCGGTGAGCAAGCGCCCGAC
GGCCGAGCCCCTGCGCGAGGTGCAGGTGCAGGTGGGCGACCACGGGCGCAAGCAGATCGCGGGCGACTTCTCCGGCCCGC
TGCGCGAGGACGGCACCCTGCTCTACCGCCTCACCGCGCTCACGCGCGATGCCGAGCTGCCGGCCGGCGGCATGAAGGAC
GACCGCACGTTCATCGCGCCTTCGCTCACCTGGAAGCCATCGAGCGACACCAGCCTCACCCTGCTTTCGCAGTTCGGGCG
CACCCGCGCGGGCGTGTTCTCGCGCACGCGCCCGGCCGTGGGCTCTCTCGTGCCGACGGCCATCGGCACGTTCATCCCGA
GCGGGCTCTTCGCCAGCGACCCGACGCACAACCGGTTCGACCTCGACACCTCGATGGTCGGCTATCTGTTTGAGCACCAC
ATCAACGACGCCTTCACCGTGCGCCAGAACGCGCGCTACGGCCACCTCGACGTGGACTACAGCGCCGTCCAGGGCCGCAA
CTTCATCACCGAGAATCCCGCCAACCCGCGCGATCCGGCCAACTTCACGACGCTGCGCCGCACCGTGTCGGGCAGCAACG
AGCGCATCCGCGCGCTGAACCTCGACAACCAGCTGGAGACGCGCCTGCGCTCGGGCGACGTGCAGCAGGCGGTGCTCGTG
GGCCTGGACTACCAGCGCACGCGCATCGACCAGACCAGCTACAGCGGCGGCTCGGCCAGCTCGCTCAACATCTACAACCC
CGTGTACGGCGGCGCGGTGCAGATCCCGGCCCCGTGGTATGACGGCGTCGCCACGCTGGCGCAGACCGGCTTCTACGTGC
AGGACCAGATCAAGTGGCGCGACCGCTGGCTGCTGACGCTGGGCGCGCGCTACGACCGCGCCAGCAGCGAAGTGGACAGC
CGCCTGGACGGCCGCCATACCAAGATCTCGGAGAGCAAGGCCACCAAGCGGGCCGGCCTCACCTACCTGGCACCGAACGG
CTGGGCGCCGTACGTGAGCTACACCGAATCCTTCGTGCCCACGGCCACGCGCAATCCCGCCACGGGCCAGCCGTTCAAGC
CCGAGACCGGCCGCCAGTACGAAGCGGGCGTGCGCTACCAACCCGAAGGCGGCAAGCAGAGCTACAGCGCGGCGATCTTC
GATCTGCGCCGCAAGAACTACCTGACCGCCGACGACAACTTCGTGCCGCGCCAGACCGGCGAGGTCCAGGTGCGCGGGCT
CGAGCTGGAAGCCTCGGCCGAAGTGCTGCCACGCCTGAACCTGGTGGGCTCCTACACCTACACGCCCACGGCCGAGATCA
CGGCCAGCAGCACCGCGCGCGAGATCGGCAAACCGCTCACGGCCGTGTCGCGCAATGCCGCCGCGCTCTGGGCCGACTAC
CGCTTCCCGAACCGCATCAAGGTGGGACTGGGCGCCCGCTTCACGGGGTCGAACTACGGCGACCTGAACGCCGCGCCGGG
CAAGGTGCCGTCCTTCACGGTGTTCGACGCGATGATCGGCTACGACATCGATCGCTGGACCTTCGCGCTGAACGTGCGCA
ACCTGACCGACAAGACCTACATCGGCAACTGCGACCAGTACGGCAACTGCTACTACGGCGACGAACGCCGCGTGATCGCG
ACCGCTACCCATCGCTGGTGA

Upstream 100 bases:

>100_bases
CCCGCCACCCAGGCCAGCGCCCAGGCAGCCCCTTCACCATCCTTCCTGGAAGCGGTGCATACCGCCGCGACCGGATCCTG
CCATCGAAGGAGCCACCCTG

Downstream 100 bases:

>100_bases
GTGGCAGGCGCACGCTTCGCCGCCGACCGCAACCCGATTGACCCGAGTCCGGTGGATGGAGCCTCCACCGGGCCAACCTG
CATATCGGCCACATGCCACC

Product: ferrichrome-iron receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MTYHLPPRRFQRRALRTTPIAAIVMAGAFTTPNAAAQTQATAPAAPTALPTVTVTEHSDPTQRSSTGTKTDTPLIETPQS
ISVIPADRMATQGATNVKEALSYSPGVIPTRFGADSRYDWISLRGFDAYAPGFYLDGMPLRNNGNWGIWPIESYGAERIE
LLRGPASVLYGQSGPGGLVNAVSKRPTAEPLREVQVQVGDHGRKQIAGDFSGPLREDGTLLYRLTALTRDAELPAGGMKD
DRTFIAPSLTWKPSSDTSLTLLSQFGRTRAGVFSRTRPAVGSLVPTAIGTFIPSGLFASDPTHNRFDLDTSMVGYLFEHH
INDAFTVRQNARYGHLDVDYSAVQGRNFITENPANPRDPANFTTLRRTVSGSNERIRALNLDNQLETRLRSGDVQQAVLV
GLDYQRTRIDQTSYSGGSASSLNIYNPVYGGAVQIPAPWYDGVATLAQTGFYVQDQIKWRDRWLLTLGARYDRASSEVDS
RLDGRHTKISESKATKRAGLTYLAPNGWAPYVSYTESFVPTATRNPATGQPFKPETGRQYEAGVRYQPEGGKQSYSAAIF
DLRRKNYLTADDNFVPRQTGEVQVRGLELEASAEVLPRLNLVGSYTYTPTAEITASSTAREIGKPLTAVSRNAAALWADY
RFPNRIKVGLGARFTGSNYGDLNAAPGKVPSFTVFDAMIGYDIDRWTFALNVRNLTDKTYIGNCDQYGNCYYGDERRVIA
TATHRW

Sequences:

>Translated_726_residues
MTYHLPPRRFQRRALRTTPIAAIVMAGAFTTPNAAAQTQATAPAAPTALPTVTVTEHSDPTQRSSTGTKTDTPLIETPQS
ISVIPADRMATQGATNVKEALSYSPGVIPTRFGADSRYDWISLRGFDAYAPGFYLDGMPLRNNGNWGIWPIESYGAERIE
LLRGPASVLYGQSGPGGLVNAVSKRPTAEPLREVQVQVGDHGRKQIAGDFSGPLREDGTLLYRLTALTRDAELPAGGMKD
DRTFIAPSLTWKPSSDTSLTLLSQFGRTRAGVFSRTRPAVGSLVPTAIGTFIPSGLFASDPTHNRFDLDTSMVGYLFEHH
INDAFTVRQNARYGHLDVDYSAVQGRNFITENPANPRDPANFTTLRRTVSGSNERIRALNLDNQLETRLRSGDVQQAVLV
GLDYQRTRIDQTSYSGGSASSLNIYNPVYGGAVQIPAPWYDGVATLAQTGFYVQDQIKWRDRWLLTLGARYDRASSEVDS
RLDGRHTKISESKATKRAGLTYLAPNGWAPYVSYTESFVPTATRNPATGQPFKPETGRQYEAGVRYQPEGGKQSYSAAIF
DLRRKNYLTADDNFVPRQTGEVQVRGLELEASAEVLPRLNLVGSYTYTPTAEITASSTAREIGKPLTAVSRNAAALWADY
RFPNRIKVGLGARFTGSNYGDLNAAPGKVPSFTVFDAMIGYDIDRWTFALNVRNLTDKTYIGNCDQYGNCYYGDERRVIA
TATHRW
>Mature_725_residues
TYHLPPRRFQRRALRTTPIAAIVMAGAFTTPNAAAQTQATAPAAPTALPTVTVTEHSDPTQRSSTGTKTDTPLIETPQSI
SVIPADRMATQGATNVKEALSYSPGVIPTRFGADSRYDWISLRGFDAYAPGFYLDGMPLRNNGNWGIWPIESYGAERIEL
LRGPASVLYGQSGPGGLVNAVSKRPTAEPLREVQVQVGDHGRKQIAGDFSGPLREDGTLLYRLTALTRDAELPAGGMKDD
RTFIAPSLTWKPSSDTSLTLLSQFGRTRAGVFSRTRPAVGSLVPTAIGTFIPSGLFASDPTHNRFDLDTSMVGYLFEHHI
NDAFTVRQNARYGHLDVDYSAVQGRNFITENPANPRDPANFTTLRRTVSGSNERIRALNLDNQLETRLRSGDVQQAVLVG
LDYQRTRIDQTSYSGGSASSLNIYNPVYGGAVQIPAPWYDGVATLAQTGFYVQDQIKWRDRWLLTLGARYDRASSEVDSR
LDGRHTKISESKATKRAGLTYLAPNGWAPYVSYTESFVPTATRNPATGQPFKPETGRQYEAGVRYQPEGGKQSYSAAIFD
LRRKNYLTADDNFVPRQTGEVQVRGLELEASAEVLPRLNLVGSYTYTPTAEITASSTAREIGKPLTAVSRNAAALWADYR
FPNRIKVGLGARFTGSNYGDLNAAPGKVPSFTVFDAMIGYDIDRWTFALNVRNLTDKTYIGNCDQYGNCYYGDERRVIAT
ATHRW

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=719, Percent_Identity=39.3602225312935, Blast_Score=430, Evalue=1e-121,
Organism=Escherichia coli, GI1787024, Length=754, Percent_Identity=25.8620689655172, Blast_Score=158, Evalue=9e-40,
Organism=Escherichia coli, GI1787344, Length=295, Percent_Identity=25.0847457627119, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79732; Mature: 79601

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYHLPPRRFQRRALRTTPIAAIVMAGAFTTPNAAAQTQATAPAAPTALPTVTVTEHSDP
CCCCCCHHHHHHHHHHCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
TQRSSTGTKTDTPLIETPQSISVIPADRMATQGATNVKEALSYSPGVIPTRFGADSRYDW
CCCCCCCCCCCCCCEECCCCCEEEECHHHHCCCCCHHHHHHCCCCCCCEEECCCCCCCCE
ISLRGFDAYAPGFYLDGMPLRNNGNWGIWPIESYGAERIELLRGPASVLYGQSGPGGLVN
EEEECCCCCCCCEEECCEEECCCCCEEEEEHHHCCHHHHHHHCCCHHHEECCCCCCHHHH
AVSKRPTAEPLREVQVQVGDHGRKQIAGDFSGPLREDGTLLYRLTALTRDAELPAGGMKD
HHHCCCCHHHHHHHEEEECCCCCHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCCCCCCCC
DRTFIAPSLTWKPSSDTSLTLLSQFGRTRAGVFSRTRPAVGSLVPTAIGTFIPSGLFASD
CCEEECCCEEECCCCCCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC
PTHNRFDLDTSMVGYLFEHHINDAFTVRQNARYGHLDVDYSAVQGRNFITENPANPRDPA
CCCCEEECCHHHHHHHHHHHCCCEEEEECCCCCCCEECCHHHHCCCCCCCCCCCCCCCCC
NFTTLRRTVSGSNERIRALNLDNQLETRLRSGDVQQAVLVGLDYQRTRIDQTSYSGGSAS
CHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCCCCCC
SLNIYNPVYGGAVQIPAPWYDGVATLAQTGFYVQDQIKWRDRWLLTLGARYDRASSEVDS
EEEECCCCCCCEEEECCCCHHHHHHHHHCCCEEEEEEEECCEEEEEECCCCCCHHHHHHH
RLDGRHTKISESKATKRAGLTYLAPNGWAPYVSYTESFVPTATRNPATGQPFKPETGRQY
HCCCCCCCCCHHHHHHHCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
EAGVRYQPEGGKQSYSAAIFDLRRKNYLTADDNFVPRQTGEVQVRGLELEASAEVLPRLN
CCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCHHHHCCEE
LVGSYTYTPTAEITASSTAREIGKPLTAVSRNAAALWADYRFPNRIKVGLGARFTGSNYG
EEECEEECCCCEEECCHHHHHHCCCHHHHCCCCEEEEEECCCCCEEEEECCEEECCCCCC
DLNAAPGKVPSFTVFDAMIGYDIDRWTFALNVRNLTDKTYIGNCDQYGNCYYGDERRVIA
CCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEEECCCCCCEECCCCCCCCCEECCCCEEEE
TATHRW
EECCCC
>Mature Secondary Structure 
TYHLPPRRFQRRALRTTPIAAIVMAGAFTTPNAAAQTQATAPAAPTALPTVTVTEHSDP
CCCCCHHHHHHHHHHCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
TQRSSTGTKTDTPLIETPQSISVIPADRMATQGATNVKEALSYSPGVIPTRFGADSRYDW
CCCCCCCCCCCCCCEECCCCCEEEECHHHHCCCCCHHHHHHCCCCCCCEEECCCCCCCCE
ISLRGFDAYAPGFYLDGMPLRNNGNWGIWPIESYGAERIELLRGPASVLYGQSGPGGLVN
EEEECCCCCCCCEEECCEEECCCCCEEEEEHHHCCHHHHHHHCCCHHHEECCCCCCHHHH
AVSKRPTAEPLREVQVQVGDHGRKQIAGDFSGPLREDGTLLYRLTALTRDAELPAGGMKD
HHHCCCCHHHHHHHEEEECCCCCHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCCCCCCCC
DRTFIAPSLTWKPSSDTSLTLLSQFGRTRAGVFSRTRPAVGSLVPTAIGTFIPSGLFASD
CCEEECCCEEECCCCCCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC
PTHNRFDLDTSMVGYLFEHHINDAFTVRQNARYGHLDVDYSAVQGRNFITENPANPRDPA
CCCCEEECCHHHHHHHHHHHCCCEEEEECCCCCCCEECCHHHHCCCCCCCCCCCCCCCCC
NFTTLRRTVSGSNERIRALNLDNQLETRLRSGDVQQAVLVGLDYQRTRIDQTSYSGGSAS
CHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCCCCCC
SLNIYNPVYGGAVQIPAPWYDGVATLAQTGFYVQDQIKWRDRWLLTLGARYDRASSEVDS
EEEECCCCCCCEEEECCCCHHHHHHHHHCCCEEEEEEEECCEEEEEECCCCCCHHHHHHH
RLDGRHTKISESKATKRAGLTYLAPNGWAPYVSYTESFVPTATRNPATGQPFKPETGRQY
HCCCCCCCCCHHHHHHHCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
EAGVRYQPEGGKQSYSAAIFDLRRKNYLTADDNFVPRQTGEVQVRGLELEASAEVLPRLN
CCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCHHHHCCEE
LVGSYTYTPTAEITASSTAREIGKPLTAVSRNAAALWADYRFPNRIKVGLGARFTGSNYG
EEECEEECCCCEEECCHHHHHHCCCHHHHCCCCEEEEEECCCCCEEEEECCEEECCCCCC
DLNAAPGKVPSFTVFDAMIGYDIDRWTFALNVRNLTDKTYIGNCDQYGNCYYGDERRVIA
CCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEEECCCCCCEECCCCCCCCCEECCCCEEEE
TATHRW
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]