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The map label for this gene is nhaR [H]

Identifier: 21242906

GI number: 21242906

Start: 2542779

End: 2543699

Strand: Reverse

Name: nhaR [H]

Synonym: XAC2171

Alternate gene names: 21242906

Gene position: 2543699-2542779 (Counterclockwise)

Preceding gene: 21242909

Following gene: 77748633

Centisome position: 49.15

GC content: 65.04

Gene sequence:

>921_bases
TTGCAGATTCGTTCGTTATTATCGAATGATATGGCCGCCTTGAACTACAACCATCTGCGCTACTTCTGGGCGGTCGCGCA
CGAGGGGAACCTCACCCGTACTGCCGAGCGTCTCAACCTCACCCAGTCGGCGCTTTCGGTGCAAATCCGCAAACTGGAGG
AGCGCCTGGGCCACGCGCTGTTCGAACGCCGCGGGCGGCAACTGTATCTGACCGAGGCCGGGCAAATCGTGCTCGACCAT
GCCGATGCGATTTTTGCCACCGGCGATGAGTTGCTTGGCACGCTGCGGCAGACGGGTGCGGCGCGGCAGGCACTGCGGGT
CGGTTCGCTTGCCACGCTCTCGCGCAACTTCCAGATGGAGTTCCTGCGGCCGCTGCTGGGCCGCACCGACATCGACCTCA
TCCTGCGATCGGGCAGCGCGGGTGAACTGCTGCGCGCGCTGGAGGCGCTCAATCTCGACGTGGTGCTGCTGAATCGGGCA
CCTGCCGGCGATGCGCTGTCCCCCTTCGTCACCCACCGGCTCGCGGAGTACCCGGTCAGCCTGGTGGGCACGCCGGATCG
GCTGGGCCATGCGGCCAGCTTCGCCGACCGCCTTCGCAGCCACCCCATCATCCTGCCCACGGTGGATAGCAGCGTGCGCA
TCGGCTTCGACGCGTTGGCCGACCGCCTGGGCGTGCGGCCGCAGATCGTGGCGGAAGTGGAAGACATGGCGATGATGCGA
CTGCTTGCCCGCGAGGACATCGGCCTGGCGGTTCTGCCGCCGATCGTGGTCAAGGACGAGATCGCAGCTGGCGCACTGAT
GGAAGGCGATCAATTGCCGGACATCGTGGAGACCTTCCATGCGGTGACCATGTCGCGACGTTTCCCGAATCCTCTGCTCA
AGCTTCTGCTTCAGCCCCCGACCAGGCCAGACAGTCCGTAA

Upstream 100 bases:

>100_bases
TGGGAGTAGATAGAGCGACAAGGCGATCCCCTAAGAACGAACGTGGTGGCGGGCCGCGCCACGATAACGACCGGTGGGGT
TGAATAAAAATTCATTGTCA

Downstream 100 bases:

>100_bases
TGCCACCCGGTTGTCCAAGGCGTGGCGCGCTGTAGACCCGCACGCGACGCGGCGCTTCTACCGGATCCAGCACCGGCAAA
CGTCTGTCGGGCAATCTGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MQIRSLLSNDMAALNYNHLRYFWAVAHEGNLTRTAERLNLTQSALSVQIRKLEERLGHALFERRGRQLYLTEAGQIVLDH
ADAIFATGDELLGTLRQTGAARQALRVGSLATLSRNFQMEFLRPLLGRTDIDLILRSGSAGELLRALEALNLDVVLLNRA
PAGDALSPFVTHRLAEYPVSLVGTPDRLGHAASFADRLRSHPIILPTVDSSVRIGFDALADRLGVRPQIVAEVEDMAMMR
LLAREDIGLAVLPPIVVKDEIAAGALMEGDQLPDIVETFHAVTMSRRFPNPLLKLLLQPPTRPDSP

Sequences:

>Translated_306_residues
MQIRSLLSNDMAALNYNHLRYFWAVAHEGNLTRTAERLNLTQSALSVQIRKLEERLGHALFERRGRQLYLTEAGQIVLDH
ADAIFATGDELLGTLRQTGAARQALRVGSLATLSRNFQMEFLRPLLGRTDIDLILRSGSAGELLRALEALNLDVVLLNRA
PAGDALSPFVTHRLAEYPVSLVGTPDRLGHAASFADRLRSHPIILPTVDSSVRIGFDALADRLGVRPQIVAEVEDMAMMR
LLAREDIGLAVLPPIVVKDEIAAGALMEGDQLPDIVETFHAVTMSRRFPNPLLKLLLQPPTRPDSP
>Mature_306_residues
MQIRSLLSNDMAALNYNHLRYFWAVAHEGNLTRTAERLNLTQSALSVQIRKLEERLGHALFERRGRQLYLTEAGQIVLDH
ADAIFATGDELLGTLRQTGAARQALRVGSLATLSRNFQMEFLRPLLGRTDIDLILRSGSAGELLRALEALNLDVVLLNRA
PAGDALSPFVTHRLAEYPVSLVGTPDRLGHAASFADRLRSHPIILPTVDSSVRIGFDALADRLGVRPQIVAEVEDMAMMR
LLAREDIGLAVLPPIVVKDEIAAGALMEGDQLPDIVETFHAVTMSRRFPNPLLKLLLQPPTRPDSP

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=288, Percent_Identity=26.7361111111111, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI157672245, Length=247, Percent_Identity=28.7449392712551, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367136, Length=250, Percent_Identity=28.4, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788297, Length=244, Percent_Identity=26.6393442622951, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787530, Length=253, Percent_Identity=25.296442687747, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790399, Length=147, Percent_Identity=29.9319727891156, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788748, Length=265, Percent_Identity=27.1698113207547, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789204, Length=259, Percent_Identity=27.4131274131274, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33736; Mature: 33736

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIRSLLSNDMAALNYNHLRYFWAVAHEGNLTRTAERLNLTQSALSVQIRKLEERLGHAL
CCHHHHHCCCHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FERRGRQLYLTEAGQIVLDHADAIFATGDELLGTLRQTGAARQALRVGSLATLSRNFQME
HHHCCCEEEEECCCEEEEECCCHHEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHH
FLRPLLGRTDIDLILRSGSAGELLRALEALNLDVVLLNRAPAGDALSPFVTHRLAEYPVS
HHHHHHCCCCCHHEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCE
LVGTPDRLGHAASFADRLRSHPIILPTVDSSVRIGFDALADRLGVRPQIVAEVEDMAMMR
EECCCHHHHHHHHHHHHHHCCCEEEEECCCCCEECHHHHHHHHCCCHHHHHHHHHHHHHH
LLAREDIGLAVLPPIVVKDEIAAGALMEGDQLPDIVETFHAVTMSRRFPNPLLKLLLQPP
HHHHCCCCEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCC
TRPDSP
CCCCCC
>Mature Secondary Structure
MQIRSLLSNDMAALNYNHLRYFWAVAHEGNLTRTAERLNLTQSALSVQIRKLEERLGHAL
CCHHHHHCCCHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FERRGRQLYLTEAGQIVLDHADAIFATGDELLGTLRQTGAARQALRVGSLATLSRNFQME
HHHCCCEEEEECCCEEEEECCCHHEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHH
FLRPLLGRTDIDLILRSGSAGELLRALEALNLDVVLLNRAPAGDALSPFVTHRLAEYPVS
HHHHHHCCCCCHHEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCE
LVGTPDRLGHAASFADRLRSHPIILPTVDSSVRIGFDALADRLGVRPQIVAEVEDMAMMR
EECCCHHHHHHHHHHHHHHCCCEEEEECCCCCEECHHHHHHHHCCCHHHHHHHHHHHHHH
LLAREDIGLAVLPPIVVKDEIAAGALMEGDQLPDIVETFHAVTMSRRFPNPLLKLLLQPP
HHHHCCCCEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCC
TRPDSP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]