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The map label for this gene is orn

Identifier: 21242783

GI number: 21242783

Start: 2383251

End: 2383835

Strand: Direct

Name: orn

Synonym: XAC2039

Alternate gene names: 21242783

Gene position: 2383251-2383835 (Clockwise)

Preceding gene: 21242782

Following gene: 21242786

Centisome position: 46.05

GC content: 61.71

Gene sequence:

>585_bases
ATGGCAGAGAACCTTGCAGGCAACGACCGACTGATCTGGATCGATCTGGAAATGACCGGCCTGGATACCGATCGCGATTC
CATCATCGAGATCGCCACCATCGTGACCGATGCGCAGTTGAACGTGCTTGCCGAGGGACCGGAACTGGCCATTGCGCATC
CGCTGGAAACCCTGGAAGCGATGGACGAATGGAACCGCAATCAACATCGCCGTTCGGGTCTGTGGCAGCGCGTGATCGAC
AGTCAGGTGACCCACGCGCAGGCCGAAGCGCAGACGGTTGCATTCCTGAGCGAGTGGATCCGTGCCGGCGCCTCGCCGAT
GTGCGGCAACTCGATCTGCCAGGATCGCCGCTTCCTGCACCGCCAGATGTCGCGCCTGGAGCGCTATTTCCATTACCGCA
ACCTGGACGTGTCCACCATCAAGGAACTCGCGCGACGGTGGGCGCCGACGGTGGCCAACGGGTTCGCCAAGAGTTCGGCC
CATACCGCCCTGAGCGATGTGCGCGATTCGATCGACGAGTTGCGCCACTATCGTCAGTTCATGGGTGCGCTTGGTGGCGA
TACCGCAGCGGGTGTGGAGAACTGA

Upstream 100 bases:

>100_bases
AGCGCGGCAAGCCGCCACTTGCGCCCTGAGCGACGTGGCCGCGGTATGATGCGCGCCCTCTTCAGCATCCGGCCGGCGAC
GGCCTCCACAGGACGGCGAT

Downstream 100 bases:

>100_bases
GAATCCGCAGGCATGTGTTGCGCACTGAAGTTCGAGCAGCAGGGTGGATCGTGTCGTCGGATGAAGTGTGCAGTGGGCGC
ACTTGAAGCACTCTCAGCAT

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MAENLAGNDRLIWIDLEMTGLDTDRDSIIEIATIVTDAQLNVLAEGPELAIAHPLETLEAMDEWNRNQHRRSGLWQRVID
SQVTHAQAEAQTVAFLSEWIRAGASPMCGNSICQDRRFLHRQMSRLERYFHYRNLDVSTIKELARRWAPTVANGFAKSSA
HTALSDVRDSIDELRHYRQFMGALGGDTAAGVEN

Sequences:

>Translated_194_residues
MAENLAGNDRLIWIDLEMTGLDTDRDSIIEIATIVTDAQLNVLAEGPELAIAHPLETLEAMDEWNRNQHRRSGLWQRVID
SQVTHAQAEAQTVAFLSEWIRAGASPMCGNSICQDRRFLHRQMSRLERYFHYRNLDVSTIKELARRWAPTVANGFAKSSA
HTALSDVRDSIDELRHYRQFMGALGGDTAAGVEN
>Mature_193_residues
AENLAGNDRLIWIDLEMTGLDTDRDSIIEIATIVTDAQLNVLAEGPELAIAHPLETLEAMDEWNRNQHRRSGLWQRVIDS
QVTHAQAEAQTVAFLSEWIRAGASPMCGNSICQDRRFLHRQMSRLERYFHYRNLDVSTIKELARRWAPTVANGFAKSSAH
TALSDVRDSIDELRHYRQFMGALGGDTAAGVEN

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=180, Percent_Identity=44.4444444444444, Blast_Score=170, Evalue=7e-43,
Organism=Escherichia coli, GI87082382, Length=174, Percent_Identity=57.4712643678161, Blast_Score=211, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17557752, Length=170, Percent_Identity=44.7058823529412, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6323088, Length=176, Percent_Identity=38.6363636363636, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21355135, Length=179, Percent_Identity=43.0167597765363, Blast_Score=160, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_XANAC (Q8PKW8)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642365.1
- ProteinModelPortal:   Q8PKW8
- SMR:   Q8PKW8
- GeneID:   1156110
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2039
- NMPDR:   fig|190486.1.peg.2009
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- ProtClustDB:   PRK05359
- BioCyc:   XAXO190486:XAC2039-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 21890; Mature: 21759

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: ACT_SITE 132-132

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENLAGNDRLIWIDLEMTGLDTDRDSIIEIATIVTDAQLNVLAEGPELAIAHPLETLEA
CCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCEEHHHHHHHHHH
MDEWNRNQHRRSGLWQRVIDSQVTHAQAEAQTVAFLSEWIRAGASPMCGNSICQDRRFLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
RQMSRLERYFHYRNLDVSTIKELARRWAPTVANGFAKSSAHTALSDVRDSIDELRHYRQF
HHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGALGGDTAAGVEN
HHHHCCCCCCCCCC
>Mature Secondary Structure 
AENLAGNDRLIWIDLEMTGLDTDRDSIIEIATIVTDAQLNVLAEGPELAIAHPLETLEA
CCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCEEHHHHHHHHHH
MDEWNRNQHRRSGLWQRVIDSQVTHAQAEAQTVAFLSEWIRAGASPMCGNSICQDRRFLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
RQMSRLERYFHYRNLDVSTIKELARRWAPTVANGFAKSSAHTALSDVRDSIDELRHYRQF
HHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGALGGDTAAGVEN
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217