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The map label for this gene is ftsK

Identifier: 21242750

GI number: 21242750

Start: 2341888

End: 2344245

Strand: Direct

Name: ftsK

Synonym: XAC2006

Alternate gene names: 21242750

Gene position: 2341888-2344245 (Clockwise)

Preceding gene: 21242745

Following gene: 21242751

Centisome position: 45.25

GC content: 65.56

Gene sequence:

>2358_bases
GTGGCAAAGCAGGTTCCCGAACGCAGCAGCAAGCCCGCAGAGGGCAAATCGTCGTCGCGCAAGACGGCGGCGGCGGACAA
TCCGCGGCGGCAGAAGCTCTGGCGCGATCTGGCCTTGATCGCGGTGGCGCCATTGCTGCTGTATCTGCTGGCCAGCCTGT
TCACTTATTCGGCGACCGATCCGGGTTGGTCGCGCACCGGCAATCTGGTCGCGCCCATCCACAACATGGGCGGCCGATTC
GGCGCGCTGGCGGCGGATGTGCTGCTGCAGCTGTTCGGGTATGTGGCCTTCCTGCTGCCGGTACTGTTGGGGGCGGTGGC
CTGGATCGCCTTGATCGGTGACCGCGAAGAGCAGACCCAAAGCGATCTGGGGCCGGCGCTGCGCCTGGTCGGCATGGTGG
GGTTCCTGATTTCGTCGACCGGCTTCCTGCACCTGCGCCTGTTCCAGGGCGAGGTGGCCGAGGCCGGCGGCATCCTGGGC
AAGTTGGTCGCCGGCTCGCTCAGCTCCCGCTTCGGTGCCTTGGGCGCGAACCTGTTCGTGCTGGTGCTGCTGCTGGTCTC
CATCACCCTGGCGACCGGCTTGTCGTGGTTTGCGGTGATGGAGCGCATCGGCAAGTGGGTGCTGGCGCTGGGGCCGCTGA
TGCAGCGCAAGACCCATCAGGCCACCGAGTGGCAGCAGACCCGGGTGATGCGCGAGGAACGCGAGGAAGTGCGCAAGGTC
GATGCGGTCAAGCAGGCCAAGCGCGAACCGGTGAAGATCGAGCCGCCGCCAGCGCCGGTAGTGGAAAAAAGCGAGCGCGC
CAAACGCGACACCCAGATTCCGATGTTCCAGGGCGTCAGCACCGACGGCTCGGACTTGCCGCCGCTGGCGCTGCTGGACG
ACCCCAAGCCGCAGACCAAGGGCTATTCCGAAGAAACCCTGGAAACGCTATCGCGGCAGATCGAGTTCAAGCTCAAGGAC
TTCCGCATCGAGGCACAAGTGGTCGGCGCCTATCCGGGACCGGTGATCACCCGTTTCGAGATCGAGCCGGCGCCGGGCAT
CAAGGTCAGCCAGATCAGCTCGCTGGACAAGGACATCGCCCGCGGGTTGTCGGTGAAATCGGTGCGTGTGGTGGACGTGA
TCCCTGGCAAGTCGGTGATCGGGCTGGAAATACCCAACGTCAGCCGCGAGATGATCTTCCTCTCCGAATTGCTGCGCTCC
AAGGAGTACGACAAGTCGGCCAGCCCGCTGACGCTTGCCCTGGGCAAGGACATCGCCGGCCGGCCGACCGTGGCCGACCT
GGCGCGCATGCCGCACTTGCTGGTCGCAGGTACCACCGGCTCGGGCAAGTCGGTGGCGGTCAATGCGATGGTGTTGAGCC
TGCTGTTCAAGGCCTCGCACAAGGAACTGCGGATGCTGATGATCGACCCGAAGATGCTCGAGTTGAGCGTCTACCAGGGC
ATCCCGCACCTGCTGGCGCCGGTGGTCACCGACATGAAGGAGGCCGCCAACGGCTTGCGCTGGTGCGTGGCCGAAATGGA
GCGCCGCTACAAGCTGATGAGCGCGGTGGGCGTGCGCAACCTGGCCGGCTTCAACAAGAAGGTCAAGGACGCCATCGACG
CCGGGCAGCCGATGATGGACCCGCTGTTCAAGCCGAACCCGGAACTGGGCGAAGCGCCGCGGCCGTTGGAGACGCTGCCG
TTCATCGTCATCTTCATCGACGAATTCGCCGACATGATGATGATCGTCGGCAAGAAGGTCGAAGAACTCATCGCGCGCCT
GGCGCAGAAGGCGCGCGCGGCCGGCATCCATCTGATCCTGGCCACGCAGCGGCCGTCGGTGGACGTTATCACCGGCCTGA
TCAAGGCCAATATCCCAACCCGCGTGGCGTTCCAGGTCAGCTCCAAGATCGACTCGCGCACCATTCTGGATCAATCCGGC
GCCGAAGCGCTGCTGGGCAACGGCGACATGCTGTATCTGCCGCCAGGCACGGCGCTGCCGGATCGCGTGCATGGCGCCTT
CGTCAGCGACGAAGAGGTACATCGCGTGGTCGAGCATCTCAAGGCGAGCGGGCCGGTGTCCTACGTCGAAGGCGTGCTGG
ACGAAGTCCAGACCATGGGCGATGGCACCGTGGTCGGTGCGACCGGCTTGCCGGAAAGCAGCGGCGGCGGTGGCGACGAG
TCGGACCCGTTGTACGACGAAGCCTTGCGCATCGTCACCGAGACCCGGCGTGCCTCGATTTCCGGCGTGCAGCGGCGTTT
GAAGATCGGCTACAACCGCGCCGCGCGTCTGATCGAAGCGATGGAAGCGGCCGGCGTCGTCAGCCCGCCCGAGCACAATG
GCGACCGTACCGTGCTGGCACCGCCGCCGCCCAAGTAG

Upstream 100 bases:

>100_bases
GCGCCTGGCTGCATGACCAGGGGGCATGCAACTGCTGAAACCGTGGCTCCGGTCGTTTATTATCAAACACTAACAGCATT
TTTCTAAGGTCTGGCTACAG

Downstream 100 bases:

>100_bases
GCGCCGGCGATGTCGTGACGCGTTTCAGGTGCAGCCCCCGGTTGGGCGCCTGCAGCAATGCCGCATTGTTGGAAGTCCGT
GCCTGTCATTGCCGGGCACA

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 785; Mature: 784

Protein sequence:

>785_residues
MAKQVPERSSKPAEGKSSSRKTAAADNPRRQKLWRDLALIAVAPLLLYLLASLFTYSATDPGWSRTGNLVAPIHNMGGRF
GALAADVLLQLFGYVAFLLPVLLGAVAWIALIGDREEQTQSDLGPALRLVGMVGFLISSTGFLHLRLFQGEVAEAGGILG
KLVAGSLSSRFGALGANLFVLVLLLVSITLATGLSWFAVMERIGKWVLALGPLMQRKTHQATEWQQTRVMREEREEVRKV
DAVKQAKREPVKIEPPPAPVVEKSERAKRDTQIPMFQGVSTDGSDLPPLALLDDPKPQTKGYSEETLETLSRQIEFKLKD
FRIEAQVVGAYPGPVITRFEIEPAPGIKVSQISSLDKDIARGLSVKSVRVVDVIPGKSVIGLEIPNVSREMIFLSELLRS
KEYDKSASPLTLALGKDIAGRPTVADLARMPHLLVAGTTGSGKSVAVNAMVLSLLFKASHKELRMLMIDPKMLELSVYQG
IPHLLAPVVTDMKEAANGLRWCVAEMERRYKLMSAVGVRNLAGFNKKVKDAIDAGQPMMDPLFKPNPELGEAPRPLETLP
FIVIFIDEFADMMMIVGKKVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRVAFQVSSKIDSRTILDQSG
AEALLGNGDMLYLPPGTALPDRVHGAFVSDEEVHRVVEHLKASGPVSYVEGVLDEVQTMGDGTVVGATGLPESSGGGGDE
SDPLYDEALRIVTETRRASISGVQRRLKIGYNRAARLIEAMEAAGVVSPPEHNGDRTVLAPPPPK

Sequences:

>Translated_785_residues
MAKQVPERSSKPAEGKSSSRKTAAADNPRRQKLWRDLALIAVAPLLLYLLASLFTYSATDPGWSRTGNLVAPIHNMGGRF
GALAADVLLQLFGYVAFLLPVLLGAVAWIALIGDREEQTQSDLGPALRLVGMVGFLISSTGFLHLRLFQGEVAEAGGILG
KLVAGSLSSRFGALGANLFVLVLLLVSITLATGLSWFAVMERIGKWVLALGPLMQRKTHQATEWQQTRVMREEREEVRKV
DAVKQAKREPVKIEPPPAPVVEKSERAKRDTQIPMFQGVSTDGSDLPPLALLDDPKPQTKGYSEETLETLSRQIEFKLKD
FRIEAQVVGAYPGPVITRFEIEPAPGIKVSQISSLDKDIARGLSVKSVRVVDVIPGKSVIGLEIPNVSREMIFLSELLRS
KEYDKSASPLTLALGKDIAGRPTVADLARMPHLLVAGTTGSGKSVAVNAMVLSLLFKASHKELRMLMIDPKMLELSVYQG
IPHLLAPVVTDMKEAANGLRWCVAEMERRYKLMSAVGVRNLAGFNKKVKDAIDAGQPMMDPLFKPNPELGEAPRPLETLP
FIVIFIDEFADMMMIVGKKVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRVAFQVSSKIDSRTILDQSG
AEALLGNGDMLYLPPGTALPDRVHGAFVSDEEVHRVVEHLKASGPVSYVEGVLDEVQTMGDGTVVGATGLPESSGGGGDE
SDPLYDEALRIVTETRRASISGVQRRLKIGYNRAARLIEAMEAAGVVSPPEHNGDRTVLAPPPPK
>Mature_784_residues
AKQVPERSSKPAEGKSSSRKTAAADNPRRQKLWRDLALIAVAPLLLYLLASLFTYSATDPGWSRTGNLVAPIHNMGGRFG
ALAADVLLQLFGYVAFLLPVLLGAVAWIALIGDREEQTQSDLGPALRLVGMVGFLISSTGFLHLRLFQGEVAEAGGILGK
LVAGSLSSRFGALGANLFVLVLLLVSITLATGLSWFAVMERIGKWVLALGPLMQRKTHQATEWQQTRVMREEREEVRKVD
AVKQAKREPVKIEPPPAPVVEKSERAKRDTQIPMFQGVSTDGSDLPPLALLDDPKPQTKGYSEETLETLSRQIEFKLKDF
RIEAQVVGAYPGPVITRFEIEPAPGIKVSQISSLDKDIARGLSVKSVRVVDVIPGKSVIGLEIPNVSREMIFLSELLRSK
EYDKSASPLTLALGKDIAGRPTVADLARMPHLLVAGTTGSGKSVAVNAMVLSLLFKASHKELRMLMIDPKMLELSVYQGI
PHLLAPVVTDMKEAANGLRWCVAEMERRYKLMSAVGVRNLAGFNKKVKDAIDAGQPMMDPLFKPNPELGEAPRPLETLPF
IVIFIDEFADMMMIVGKKVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRVAFQVSSKIDSRTILDQSGA
EALLGNGDMLYLPPGTALPDRVHGAFVSDEEVHRVVEHLKASGPVSYVEGVLDEVQTMGDGTVVGATGLPESSGGGGDES
DPLYDEALRIVTETRRASISGVQRRLKIGYNRAARLIEAMEAAGVVSPPEHNGDRTVLAPPPPK

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=498, Percent_Identity=62.4497991967871, Blast_Score=617, Evalue=1e-178,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_XANAC (Q8PL00)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642332.1
- ProteinModelPortal:   Q8PL00
- GeneID:   1156077
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2006
- NMPDR:   fig|190486.1.peg.1976
- HOGENOM:   HBG662140
- OMA:   FKVMDVT
- ProtClustDB:   CLSK446259
- BioCyc:   XAXO190486:XAC2006-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 84990; Mature: 84859

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xed31570)-; HASH(0xb7ec52c)-; HASH(0xfdccb00)-;

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQVPERSSKPAEGKSSSRKTAAADNPRRQKLWRDLALIAVAPLLLYLLASLFTYSATD
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PGWSRTGNLVAPIHNMGGRFGALAADVLLQLFGYVAFLLPVLLGAVAWIALIGDREEQTQ
CCCCCCCCEEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SDLGPALRLVGMVGFLISSTGFLHLRLFQGEVAEAGGILGKLVAGSLSSRFGALGANLFV
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
LVLLLVSITLATGLSWFAVMERIGKWVLALGPLMQRKTHQATEWQQTRVMREEREEVRKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAVKQAKREPVKIEPPPAPVVEKSERAKRDTQIPMFQGVSTDGSDLPPLALLDDPKPQTK
HHHHHHHCCCCEECCCCCCCCCCHHHHHCCCCCCCEECCCCCCCCCCCEEEECCCCCCCC
GYSEETLETLSRQIEFKLKDFRIEAQVVGAYPGPVITRFEIEPAPGIKVSQISSLDKDIA
CCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
RGLSVKSVRVVDVIPGKSVIGLEIPNVSREMIFLSELLRSKEYDKSASPLTLALGKDIAG
CCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
RPTVADLARMPHLLVAGTTGSGKSVAVNAMVLSLLFKASHKELRMLMIDPKMLELSVYQG
CCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCHHHEEEEEECCHHHHHHHHHC
IPHLLAPVVTDMKEAANGLRWCVAEMERRYKLMSAVGVRNLAGFNKKVKDAIDAGQPMMD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHH
PLFKPNPELGEAPRPLETLPFIVIFIDEFADMMMIVGKKVEELIARLAQKARAAGIHLIL
HCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
ATQRPSVDVITGLIKANIPTRVAFQVSSKIDSRTILDQSGAEALLGNGDMLYLPPGTALP
ECCCCCHHHHHHHHHCCCCCEEEEEEHHCCCHHHHHCCCCCCCEECCCCEEEECCCCCCC
DRVHGAFVSDEEVHRVVEHLKASGPVSYVEGVLDEVQTMGDGTVVGATGLPESSGGGGDE
CHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCC
SDPLYDEALRIVTETRRASISGVQRRLKIGYNRAARLIEAMEAAGVVSPPEHNGDRTVLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEC
PPPPK
CCCCH
>Mature Secondary Structure 
AKQVPERSSKPAEGKSSSRKTAAADNPRRQKLWRDLALIAVAPLLLYLLASLFTYSATD
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PGWSRTGNLVAPIHNMGGRFGALAADVLLQLFGYVAFLLPVLLGAVAWIALIGDREEQTQ
CCCCCCCCEEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SDLGPALRLVGMVGFLISSTGFLHLRLFQGEVAEAGGILGKLVAGSLSSRFGALGANLFV
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
LVLLLVSITLATGLSWFAVMERIGKWVLALGPLMQRKTHQATEWQQTRVMREEREEVRKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAVKQAKREPVKIEPPPAPVVEKSERAKRDTQIPMFQGVSTDGSDLPPLALLDDPKPQTK
HHHHHHHCCCCEECCCCCCCCCCHHHHHCCCCCCCEECCCCCCCCCCCEEEECCCCCCCC
GYSEETLETLSRQIEFKLKDFRIEAQVVGAYPGPVITRFEIEPAPGIKVSQISSLDKDIA
CCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
RGLSVKSVRVVDVIPGKSVIGLEIPNVSREMIFLSELLRSKEYDKSASPLTLALGKDIAG
CCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
RPTVADLARMPHLLVAGTTGSGKSVAVNAMVLSLLFKASHKELRMLMIDPKMLELSVYQG
CCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCHHHEEEEEECCHHHHHHHHHC
IPHLLAPVVTDMKEAANGLRWCVAEMERRYKLMSAVGVRNLAGFNKKVKDAIDAGQPMMD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHH
PLFKPNPELGEAPRPLETLPFIVIFIDEFADMMMIVGKKVEELIARLAQKARAAGIHLIL
HCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
ATQRPSVDVITGLIKANIPTRVAFQVSSKIDSRTILDQSGAEALLGNGDMLYLPPGTALP
ECCCCCHHHHHHHHHCCCCCEEEEEEHHCCCHHHHHCCCCCCCEECCCCEEEECCCCCCC
DRVHGAFVSDEEVHRVVEHLKASGPVSYVEGVLDEVQTMGDGTVVGATGLPESSGGGGDE
CHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCC
SDPLYDEALRIVTETRRASISGVQRRLKIGYNRAARLIEAMEAAGVVSPPEHNGDRTVLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEC
PPPPK
CCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12024217