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The map label for this gene is dapB

Identifier: 21242604

GI number: 21242604

Start: 2155056

End: 2155772

Strand: Direct

Name: dapB

Synonym: XAC1860

Alternate gene names: 21242604

Gene position: 2155056-2155772 (Clockwise)

Preceding gene: 21242603

Following gene: 21242605

Centisome position: 41.64

GC content: 68.9

Gene sequence:

>717_bases
ATGACAACCTCTGCTGTGAAAGTTCTGATCCACGGCGCCTCCGGGCGGATGGGCAAGGCGTTGCTGCGATTGGCTGCCGA
AGACCAGACCTTGCAGGTGGTCGGCGCCGTGGTGGGCCGCTCGCCCTCCCAGCGCGTGGTCGATGGGGTGCCGTTTTTCG
CTGCCAGCGAACTCGGCGGCGCGCCTGCGTTCGATGTGGCGATCGACTTCAGTTTGCCGCAGGGCTTCGCACCGATCCTG
GCGTTGTGCGCGCAGCGCGGCAAGCCGCTGGTGTCCGGCACCACCGGGCTCGACGAGGCGCAGCGTGCGGCCTTGCGCGA
TGCCGCCCAGCAGATTGCGCTGGTCTGGGCGTCCAACTTCAGTCTGGGCGTTGCGGTGCTGACAGAGCTGGTGGAGCGCG
CGGCCGGCACCTTGCCGGGGTGGGACTGCGACATCCTCGAATCGCATCACGTGCACAAGCAGGACGCGCCCTCCGGCACT
GCATTGACGCTGGGCGAGGCGGCGACCGGCAGCGGCGCGCAGCCGCGCTATGTCAGCTTGCGTGCCGGCGACATCGTTGG
CGAGCACACCGTGCAGTTCACCGGGCTGGGCGAGCGGGTCGAGCTGGTGCACCGCGCGACCAACCGCGACATCTTCGCGC
GCGGTGCCTTGCATGCGGCCAAGCGGCTGATCGGCAAGCCGGCAGGCAGCTACCGCGTACGCGATCTGGTGCTGTAG

Upstream 100 bases:

>100_bases
GCATCGCGCGCAATGGGGCACCGCAGTGACGAATCGCTAATCCCAGATCCCCAATCCCGGCTATCGTGTACCACCCACAT
CGCCAAGCCAGCCTGCCGCC

Downstream 100 bases:

>100_bases
GCGCGCCGCAGCCATGCATGAACGGTAGCCGCACGTCGCGGCCTATTCATGCCTCAACGTTGATGCCGTGACGGCATCCG
ATGCTCTTCAGACTGGCATG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTTSAVKVLIHGASGRMGKALLRLAAEDQTLQVVGAVVGRSPSQRVVDGVPFFAASELGGAPAFDVAIDFSLPQGFAPIL
ALCAQRGKPLVSGTTGLDEAQRAALRDAAQQIALVWASNFSLGVAVLTELVERAAGTLPGWDCDILESHHVHKQDAPSGT
ALTLGEAATGSGAQPRYVSLRAGDIVGEHTVQFTGLGERVELVHRATNRDIFARGALHAAKRLIGKPAGSYRVRDLVL

Sequences:

>Translated_238_residues
MTTSAVKVLIHGASGRMGKALLRLAAEDQTLQVVGAVVGRSPSQRVVDGVPFFAASELGGAPAFDVAIDFSLPQGFAPIL
ALCAQRGKPLVSGTTGLDEAQRAALRDAAQQIALVWASNFSLGVAVLTELVERAAGTLPGWDCDILESHHVHKQDAPSGT
ALTLGEAATGSGAQPRYVSLRAGDIVGEHTVQFTGLGERVELVHRATNRDIFARGALHAAKRLIGKPAGSYRVRDLVL
>Mature_237_residues
TTSAVKVLIHGASGRMGKALLRLAAEDQTLQVVGAVVGRSPSQRVVDGVPFFAASELGGAPAFDVAIDFSLPQGFAPILA
LCAQRGKPLVSGTTGLDEAQRAALRDAAQQIALVWASNFSLGVAVLTELVERAAGTLPGWDCDILESHHVHKQDAPSGTA
LTLGEAATGSGAQPRYVSLRAGDIVGEHTVQFTGLGERVELVHRATNRDIFARGALHAAKRLIGKPAGSYRVRDLVL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=274, Percent_Identity=40.1459854014599, Blast_Score=155, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_XANAC (Q8PLE0)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642186.1
- ProteinModelPortal:   Q8PLE0
- SMR:   Q8PLE0
- GeneID:   1155931
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1860
- NMPDR:   fig|190486.1.peg.1830
- HOGENOM:   HBG594002
- OMA:   GALKACE
- ProtClustDB:   PRK00048
- BioCyc:   XAXO190486:XAC1860-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 24845; Mature: 24713

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSAVKVLIHGASGRMGKALLRLAAEDQTLQVVGAVVGRSPSQRVVDGVPFFAASELGG
CCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCCCHHHHHCCC
APAFDVAIDFSLPQGFAPILALCAQRGKPLVSGTTGLDEAQRAALRDAAQQIALVWASNF
CCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
SLGVAVLTELVERAAGTLPGWDCDILESHHVHKQDAPSGTALTLGEAATGSGAQPRYVSL
CHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEE
RAGDIVGEHTVQFTGLGERVELVHRATNRDIFARGALHAAKRLIGKPAGSYRVRDLVL
ECCCCCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHEECC
>Mature Secondary Structure 
TTSAVKVLIHGASGRMGKALLRLAAEDQTLQVVGAVVGRSPSQRVVDGVPFFAASELGG
CCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCCCHHHHHCCC
APAFDVAIDFSLPQGFAPILALCAQRGKPLVSGTTGLDEAQRAALRDAAQQIALVWASNF
CCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
SLGVAVLTELVERAAGTLPGWDCDILESHHVHKQDAPSGTALTLGEAATGSGAQPRYVSL
CHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEE
RAGDIVGEHTVQFTGLGERVELVHRATNRDIFARGALHAAKRLIGKPAGSYRVRDLVL
ECCCCCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217