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The map label for this gene is fhaC [H]

Identifier: 21242558

GI number: 21242558

Start: 2089806

End: 2091506

Strand: Direct

Name: fhaC [H]

Synonym: XAC1814

Alternate gene names: 21242558

Gene position: 2089806-2091506 (Clockwise)

Preceding gene: 21242545

Following gene: 21242559

Centisome position: 40.38

GC content: 65.31

Gene sequence:

>1701_bases
ATGTGGATGCGATCGGCGCCCTTGGCGCTGGCGGTTTGCCTATGGGCAATCGCCGGGCTGGCGGCTGCACAACAGTCGGC
ACCGACAACGCTGGATCGGCAGGAGCAATTGCGCCAGGCCGAGGAGATTCAGCGTCGCCAGGAACAGGAGCGCCAGGCGC
CCTTCGCCGGCCCGCGCGAGGAAGCCGACCGTGTGGACGCGCGCAGCACCGTGCTGCCCAAGGAAGACCTGTGTTTTTCG
ATCACGCGCGTGCGCCTGTCCGGCGCGGGCGATGATGCGGCGCGCTTTGCGTGGTTGTGGACGTCGCTGCGCCGTTACCA
AGGCCGCTGCATCGGGCACGCCGGTATCGACATCATCCGGCGCCGCGCATTGGATCAGTTGGTTGCACGCGGATTGGTCA
CCACCCGCATCGGCGTGCCGGAACAGGATCTGTCGCGCGGCGAGCTACGTTTCGAACTGATGCCCGGCCGTTTGCGTGCG
GTGCGCGTGGTCTCCGATACCGAAGGCGCGCACTGGAAAACCGCATTGCCGCTGCGTACGGGCGATTTGCTGGATTTGCG
TGCCATCGAGCAAGCGGTAGAGCAGTTCAAGCGGCTGCCATCGCAGGACGCCAAGATCGATATCGCGCCGGGCGAGGCAC
CGGGCGAATCGGATCTGGTGATCACCTTGCAGCATGGGCGGCGCTGGCGCGGTGTGGCCAATGCCGACGATTCAGGGGTG
GAGGCGACCGGTCGCGTGCAAGGTGGATTGGACGTTTCGCTGGATAACCCACTGGGTCTCAACGATCTGCTCAGCATTGG
CTACAGCCATGACTTGGCCACGCGCGACGAAGAACGCGGCACACGCGGCAACAGCCTGAGTTACAGCCTGCCATGGGGAT
GGTGGACGTTTGCGCTGTCGGCATCGTCGTACCGCTATCACCAGCGCGTGGATGGTTTTTTGCAGACCTTCCGGTCCAGT
GGCGAGTCCGGTAACGCGCAGCTGGATATTCAGCGCGTGCTGCATCGCGATGGCACCAGCAAGACCTCGGCCGGTGTGGT
GATTGGCCGGCGGCGTGCGCGCAGTTATCTGGATGGCGTGGAGATCGGCATCCAGCGGCGCGATACCAGCAGCGCGGAGT
TCTACCTCACGCACCGGCGCTATCTGGGCACGATGCAGCTGGACATGCGTCTGGCGCATCGGCGCGGCACGCCGTGGTTC
AACAGCCAGTGGACCGGCTACGCCCCGCAGATCGGCTTCCCGACATTTCGCTATGGGGTGACTACGCTGGACATCAGCAC
GGCCCTGCCGTTCAAGCTGGGCCCGGTGCCGATGGCGTGGGAAAGCAGCCTGCGTGCACAGACCGCTGGCGAACTGTTGC
TGGGTTCGGAGTTCGTCACCATTGGTGGCCGTTACAGCGTGCGCGGTTTCGACGGCGAGGCGACGCTCGGGGCGGAAAAG
GGCGCGTACTGGCGCAATACCTTCAGCTTCCCCGTGCAGCAGATCGGGTTGACGCCCTACCTGGGCCTGGACGCCGGCCG
CATCGATGGCACCAGCGCCAACGGGCTGCGCGGCCGCAGTCTGGTCGGTGGCGCGGTGGGTCTGCGTGGCGGTTGGTTCG
GCGCCAGCGTGGATGCATTTGCTGGTTGGGCGATTCACCGTCCCGACGGATTTGGAAGTGCGCAGCCGGCCTACGGCGCG
CGTGTGATTTACCAGTTTTGA

Upstream 100 bases:

>100_bases
TTCAGCGTGCTGACGGATTGCGCCGCCGCTTTGGTGGCCAGGTACGTTGATGCGGGTGACGGCGCGCAGTAGCGCGACCG
CCGCACAGGGGGCAGGACAG

Downstream 100 bases:

>100_bases
CACGGATCGCGTCGCCAGCCGGCTGCGCGTTTGTTGATGGATGACGCCAACCGGCGGCGAGAGAGAAACGATGGACAACG
AAGCGATGCGCGTGCGTGGT

Product: outer membrane hemolysin activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MWMRSAPLALAVCLWAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPREEADRVDARSTVLPKEDLCFS
ITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGHAGIDIIRRRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLRA
VRVVSDTEGAHWKTALPLRTGDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVANADDSGV
EATGRVQGGLDVSLDNPLGLNDLLSIGYSHDLATRDEERGTRGNSLSYSLPWGWWTFALSASSYRYHQRVDGFLQTFRSS
GESGNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGVEIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWF
NSQWTGYAPQIGFPTFRYGVTTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGGRYSVRGFDGEATLGAEK
GAYWRNTFSFPVQQIGLTPYLGLDAGRIDGTSANGLRGRSLVGGAVGLRGGWFGASVDAFAGWAIHRPDGFGSAQPAYGA
RVIYQF

Sequences:

>Translated_566_residues
MWMRSAPLALAVCLWAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPREEADRVDARSTVLPKEDLCFS
ITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGHAGIDIIRRRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLRA
VRVVSDTEGAHWKTALPLRTGDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVANADDSGV
EATGRVQGGLDVSLDNPLGLNDLLSIGYSHDLATRDEERGTRGNSLSYSLPWGWWTFALSASSYRYHQRVDGFLQTFRSS
GESGNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGVEIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWF
NSQWTGYAPQIGFPTFRYGVTTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGGRYSVRGFDGEATLGAEK
GAYWRNTFSFPVQQIGLTPYLGLDAGRIDGTSANGLRGRSLVGGAVGLRGGWFGASVDAFAGWAIHRPDGFGSAQPAYGA
RVIYQF
>Mature_566_residues
MWMRSAPLALAVCLWAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPREEADRVDARSTVLPKEDLCFS
ITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGHAGIDIIRRRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLRA
VRVVSDTEGAHWKTALPLRTGDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVANADDSGV
EATGRVQGGLDVSLDNPLGLNDLLSIGYSHDLATRDEERGTRGNSLSYSLPWGWWTFALSASSYRYHQRVDGFLQTFRSS
GESGNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGVEIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWF
NSQWTGYAPQIGFPTFRYGVTTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGGRYSVRGFDGEATLGAEK
GAYWRNTFSFPVQQIGLTPYLGLDAGRIDGTSANGLRGRSLVGGAVGLRGGWFGASVDAFAGWAIHRPDGFGSAQPAYGA
RVIYQF

Specific function: Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 62411; Mature: 62411

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWMRSAPLALAVCLWAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPRE
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
EADRVDARSTVLPKEDLCFSITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGHAGIDIIR
HHHHCCCHHCCCCCHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEECHHHHHHHH
RRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLRAVRVVSDTEGAHWKTALPLRT
HHHHHHHHHCCHHEEECCCCHHCCCCCCEEEEECCCCEEEEEEEECCCCCCEEEECCCCC
GDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVANADDSGV
CCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
EATGRVQGGLDVSLDNPLGLNDLLSIGYSHDLATRDEERGTRGNSLSYSLPWGWWTFALS
CEECEECCCEEEEECCCCCHHHHHHCCCCCCCCCCCHHCCCCCCCEEEECCCCEEEEEEC
ASSYRYHQRVDGFLQTFRSSGESGNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGV
CCCHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHCCCCCCCCCCEEEEHHHHHHHHCHH
EIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWFNSQWTGYAPQIGFPTFRYGV
HEEEEECCCCCCEEEEEEHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCE
TTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGGRYSVRGFDGEATLGAEK
EEEEECCCCCCEECCCCCHHHHHHHHHHCCCEEECCEEEEECCEEEEECCCCCCCCCCCC
GAYWRNTFSFPVQQIGLTPYLGLDAGRIDGTSANGLRGRSLVGGAVGLRGGWFGASVDAF
CCCCCCCCCCCHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCHHHH
AGWAIHRPDGFGSAQPAYGARVIYQF
CCEEEECCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MWMRSAPLALAVCLWAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPRE
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
EADRVDARSTVLPKEDLCFSITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGHAGIDIIR
HHHHCCCHHCCCCCHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEECHHHHHHHH
RRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLRAVRVVSDTEGAHWKTALPLRT
HHHHHHHHHCCHHEEECCCCHHCCCCCCEEEEECCCCEEEEEEEECCCCCCEEEECCCCC
GDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVANADDSGV
CCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
EATGRVQGGLDVSLDNPLGLNDLLSIGYSHDLATRDEERGTRGNSLSYSLPWGWWTFALS
CEECEECCCEEEEECCCCCHHHHHHCCCCCCCCCCCHHCCCCCCCEEEECCCCEEEEEEC
ASSYRYHQRVDGFLQTFRSSGESGNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGV
CCCHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHCCCCCCCCCCEEEEHHHHHHHHCHH
EIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWFNSQWTGYAPQIGFPTFRYGV
HEEEEECCCCCCEEEEEEHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCE
TTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGGRYSVRGFDGEATLGAEK
EEEEECCCCCCEECCCCCHHHHHHHHHHCCCEEECCEEEEECCEEEEECCCCCCCCCCCC
GAYWRNTFSFPVQQIGLTPYLGLDAGRIDGTSANGLRGRSLVGGAVGLRGGWFGASVDAF
CCCCCCCCCCCHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCHHHH
AGWAIHRPDGFGSAQPAYGARVIYQF
CCEEEECCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]