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The map label for this gene is sglT [H]

Identifier: 21242539

GI number: 21242539

Start: 2064992

End: 2066554

Strand: Direct

Name: sglT [H]

Synonym: XAC1794

Alternate gene names: 21242539

Gene position: 2064992-2066554 (Clockwise)

Preceding gene: 21242538

Following gene: 21242541

Centisome position: 39.9

GC content: 63.28

Gene sequence:

>1563_bases
GTGGGTTTGGCGACGTTGGATATCGTGATCGTGCTGGTCTATCTGGCCGGCATCTTCGTGCTCGCGCAGTGGGTCTCGCG
CGAGAAGGCAGGCCATAGCAAGAGCGCCGAGGATTATTTCCTGGCGAGCAAGTCGCTGCCGTGGTGGGCGATCGGCGCAT
CGCTGATCGCTGCGAACATTTCGGCCGAACAGATCATTGGCATGGCCGGTTCGGGCTATGCGATCGGTCTGGCGATCGCC
TCCTACGAATGGATGGCGGCGCTGACCCTGCTGATCGTCGGCAAGTTCTTCCTGCCGATCTTCCTGCGCAACGGCATCTA
CACCATGCCGCAGTTTTTGGAGCAGCGTTACGGCACGTGGATCCGCACGCTGATGGCAGTGTTCTGGCTGCTGCTGTACG
TGTTCGTCAACCTGACCTCGATCCTGTGGCTGGGATCGATCGCGGTCAGCCAGGTCACCGGCATGGACCAGACCCTGGCG
CTGGCGTTGATCGGCGTGTTCGCGCTGGTCTACCAGCTGTACGGCGGGCTGAAGGCGGTGGCGCTGACCGACATCGTGCA
GGTCACCCTGCTGGTGCTGGGCGGCCTGCTGGTGGCGGGGCTGACCCTGGCGCGCATTGGCGACGGTGCCGGCGTGCTGG
CCGGCTTCCAGCACCTGTGGACTGCGCACCCCGATCACTTCCACATGATCCTGACCAGGGACAACCCGTTCTACAAGGAT
CTGCCGGGCCTGAGCGTGCTGCTCGGCGGGCTGTGGGTGATGAACATCAGTTACTGGGGTTTCAATCAGTACATCATCCA
GCGCGCGCTGGCCGCCAAGAACATCGGCGAGGCGCAAAAGGGCATGGTGTTCGCCGCGTTCCTGAAGCTGCTGATGCCGT
TGGTGATCGTGGTGCCGGGCATTGCCGCAGTGGTGCTGGCGCCGGATCTGGCCAAGCCCGACCAGGCCTACCCGACCATG
ATGCAGTTGTTGCCGACCGGCATCCTGGGCCTGGTGTTTGCCGCGTTGGTTGCGGCGATCGTGGCCTCGCTGGCCTCGAA
GATCAATTCGGTGGCGACGATCTTCACCCTGGATTTCTACGCCAAGTTCCGTCCGCAGACCGAGCAGAAGCAGCTGGTGC
GCGTGGGGCGTCTCGTGGCCGCCGCCTCGGTGCTGATCGGCATCCTCACTGCGCGGCCGTTGCTGGGCAACTTCGATCAG
GGCTTTCAGTTCATCCAGGAATTCACCGGCTTCTTTACCCCAGGCGTGGTGGTGATCTTCATGCTTGGCCTGTTCTGGAA
GCGGGCCAACGAAGCCGGCGCGCTGACCGCGGCGATCGGCTCGGTGGTGTTGTCGTTCGCGCTCAAGTTCGCCTGGCCCG
AACTGCCGTTCATGGACCGCATCGGTGTGGTGTTCGTTGCCGCGCTGGTATTGGCGGTGGTGGTGTCGCTGCTGACGCCT
GCCACGCAGGCACGCGATCTGATCCGTACCAACGACGTTGCCTACGGCACCACGCTCGGCTTCAAGATCGGCGCCGCCGG
CGTGATCGCGATTCTGATCGTGCTGTACACCGTGTTCTGGTAA

Upstream 100 bases:

>100_bases
GGTTCGCCGCGTTGCCGTGGCGCATGCTGTGCGTTGCGGCGGCATTCTGCAGGCCTGTCTGGCGTTCGACGCACACCCCA
AAGCCAGACAGGAGAGTGCA

Downstream 100 bases:

>100_bases
GCAGCGATGTCTTGAAACGCAGCGCGGCGTGGCACCTTGGTGTCGCGCCGCGCTGCGTTGACAGCCTGCCGTTTCGGAGG
CGCCAGCCCTCGTCAAGCGG

Product: sodium/glucose cotransport protein

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MGLATLDIVIVLVYLAGIFVLAQWVSREKAGHSKSAEDYFLASKSLPWWAIGASLIAANISAEQIIGMAGSGYAIGLAIA
SYEWMAALTLLIVGKFFLPIFLRNGIYTMPQFLEQRYGTWIRTLMAVFWLLLYVFVNLTSILWLGSIAVSQVTGMDQTLA
LALIGVFALVYQLYGGLKAVALTDIVQVTLLVLGGLLVAGLTLARIGDGAGVLAGFQHLWTAHPDHFHMILTRDNPFYKD
LPGLSVLLGGLWVMNISYWGFNQYIIQRALAAKNIGEAQKGMVFAAFLKLLMPLVIVVPGIAAVVLAPDLAKPDQAYPTM
MQLLPTGILGLVFAALVAAIVASLASKINSVATIFTLDFYAKFRPQTEQKQLVRVGRLVAAASVLIGILTARPLLGNFDQ
GFQFIQEFTGFFTPGVVVIFMLGLFWKRANEAGALTAAIGSVVLSFALKFAWPELPFMDRIGVVFVAALVLAVVVSLLTP
ATQARDLIRTNDVAYGTTLGFKIGAAGVIAILIVLYTVFW

Sequences:

>Translated_520_residues
MGLATLDIVIVLVYLAGIFVLAQWVSREKAGHSKSAEDYFLASKSLPWWAIGASLIAANISAEQIIGMAGSGYAIGLAIA
SYEWMAALTLLIVGKFFLPIFLRNGIYTMPQFLEQRYGTWIRTLMAVFWLLLYVFVNLTSILWLGSIAVSQVTGMDQTLA
LALIGVFALVYQLYGGLKAVALTDIVQVTLLVLGGLLVAGLTLARIGDGAGVLAGFQHLWTAHPDHFHMILTRDNPFYKD
LPGLSVLLGGLWVMNISYWGFNQYIIQRALAAKNIGEAQKGMVFAAFLKLLMPLVIVVPGIAAVVLAPDLAKPDQAYPTM
MQLLPTGILGLVFAALVAAIVASLASKINSVATIFTLDFYAKFRPQTEQKQLVRVGRLVAAASVLIGILTARPLLGNFDQ
GFQFIQEFTGFFTPGVVVIFMLGLFWKRANEAGALTAAIGSVVLSFALKFAWPELPFMDRIGVVFVAALVLAVVVSLLTP
ATQARDLIRTNDVAYGTTLGFKIGAAGVIAILIVLYTVFW
>Mature_519_residues
GLATLDIVIVLVYLAGIFVLAQWVSREKAGHSKSAEDYFLASKSLPWWAIGASLIAANISAEQIIGMAGSGYAIGLAIAS
YEWMAALTLLIVGKFFLPIFLRNGIYTMPQFLEQRYGTWIRTLMAVFWLLLYVFVNLTSILWLGSIAVSQVTGMDQTLAL
ALIGVFALVYQLYGGLKAVALTDIVQVTLLVLGGLLVAGLTLARIGDGAGVLAGFQHLWTAHPDHFHMILTRDNPFYKDL
PGLSVLLGGLWVMNISYWGFNQYIIQRALAAKNIGEAQKGMVFAAFLKLLMPLVIVVPGIAAVVLAPDLAKPDQAYPTMM
QLLPTGILGLVFAALVAAIVASLASKINSVATIFTLDFYAKFRPQTEQKQLVRVGRLVAAASVLIGILTARPLLGNFDQG
FQFIQEFTGFFTPGVVVIFMLGLFWKRANEAGALTAAIGSVVLSFALKFAWPELPFMDRIGVVFVAALVLAVVVSLLTPA
TQARDLIRTNDVAYGTTLGFKIGAAGVIAILIVLYTVFW

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG4146

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI17941285, Length=467, Percent_Identity=35.3319057815846, Blast_Score=253, Evalue=4e-67,
Organism=Homo sapiens, GI110835708, Length=555, Percent_Identity=34.0540540540541, Blast_Score=245, Evalue=8e-65,
Organism=Homo sapiens, GI4507031, Length=467, Percent_Identity=31.6916488222698, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI4507033, Length=473, Percent_Identity=31.0782241014799, Blast_Score=227, Evalue=3e-59,
Organism=Homo sapiens, GI14140236, Length=468, Percent_Identity=27.991452991453, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI206597483, Length=450, Percent_Identity=34.2222222222222, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI109659836, Length=584, Percent_Identity=33.5616438356164, Blast_Score=210, Evalue=3e-54,
Organism=Homo sapiens, GI109659839, Length=600, Percent_Identity=32.5, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI206597487, Length=475, Percent_Identity=32.4210526315789, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI4507035, Length=433, Percent_Identity=25.635103926097, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI157671931, Length=426, Percent_Identity=24.8826291079812, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI256985183, Length=429, Percent_Identity=25.4079254079254, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI167466278, Length=460, Percent_Identity=23.4782608695652, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI310128183, Length=499, Percent_Identity=22.8456913827655, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790113, Length=478, Percent_Identity=31.3807531380753, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI87082237, Length=447, Percent_Identity=25.503355704698, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787251, Length=403, Percent_Identity=24.5657568238213, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32566512, Length=385, Percent_Identity=22.5974025974026, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24651739, Length=454, Percent_Identity=25.1101321585903, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28573698, Length=475, Percent_Identity=24.6315789473684, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24651741, Length=429, Percent_Identity=23.3100233100233, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI161076631, Length=350, Percent_Identity=27.1428571428571, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI281362918, Length=435, Percent_Identity=23.2183908045977, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24645928, Length=356, Percent_Identity=26.4044943820225, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221459584, Length=414, Percent_Identity=23.6714975845411, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24640370, Length=359, Percent_Identity=28.4122562674095, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24650192, Length=369, Percent_Identity=25.4742547425474, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221459586, Length=513, Percent_Identity=23.7816764132554, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648033, Length=403, Percent_Identity=25.3101736972705, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356865, Length=403, Percent_Identity=25.3101736972705, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221459588, Length=389, Percent_Identity=23.9074550128535, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24641117, Length=476, Percent_Identity=23.109243697479, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920916, Length=372, Percent_Identity=26.0752688172043, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281362054, Length=379, Percent_Identity=23.4828496042216, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362052, Length=379, Percent_Identity=23.4828496042216, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362050, Length=379, Percent_Identity=23.4828496042216, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648056, Length=379, Percent_Identity=23.4828496042216, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356827, Length=379, Percent_Identity=23.4828496042216, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574994, Length=430, Percent_Identity=24.1860465116279, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281364280, Length=343, Percent_Identity=24.7813411078717, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 56174; Mature: 56043

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHCCCCCCCHHCHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GLATLDIVIVLVYLAGIFVLAQWVSREKAGHSKSAEDYFLASKSLPWWAIGASLIAANI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCC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CHHHHHHHHHCCCCCCCHHCHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]