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The map label for this gene is xylB [H]

Identifier: 21242521

GI number: 21242521

Start: 2042330

End: 2043823

Strand: Direct

Name: xylB [H]

Synonym: XAC1775

Alternate gene names: 21242521

Gene position: 2042330-2043823 (Clockwise)

Preceding gene: 21242520

Following gene: 77748610

Centisome position: 39.46

GC content: 67.4

Gene sequence:

>1494_bases
ATGAGCTTGTATGTAGGACTGGATGTGGGCACGCAGAGCGTCAAGCTGGTGGCCTACGATCCGCAGGATCGCGCCGTGGT
CGCCACCATCGCAGCGCCCATGGAGCTGATCAGCCGCGACGACGGCACCCGCGAACAACAGGCGCAGTGGTGGATCGACG
GCATCGTGCATTGCTTCGCGCAGCTCGATGGCGAACAGCGTGCGCGCGTGCGCGGCATCTCCGTCTCCGGCCAGCAACAC
GGCTTCGTGCCGGTGGCCGCCGACGGCAGCGTCACCGCGCCGGTCAAGCTGTGGTGCGATACCAGCACCGCGCTGGAATG
CGATGAAATCATGGCCGCCGTCGGCGGCGCCGCAGGCAGCGTGGCCGCGGCAGGCAACCCCATCATGGCCGGCTATACCG
CCTCCAAATTGCCGTGGACGCGCAAGCATCGTCCCGATGCGTATGCCGCGATGACCACGGTGATGCTGCCGCACGACTAC
GTGAACTTTTGGCTCACCGGCGAGCGCTTTGCCGAAGTGGGCGATGCCTCCGGTACCGGCTGGCTGGACGTGCGCACGCG
GCAGTGGTCCGAGCGCATGCTGAGTGCGGTCGACGCACAACGCGACCTGCGCGAGGCGTTGCCGCCGCTGGTGGACACGG
GCGCGGTCTATGCCTTATCCGATGCCGCCGCCCAGGCATTGAATCTGCCGGCCGGCGTGCGCGTCACCACCGGCGGCGGC
GACAACATGATGGCCGCCATCGGCACCGGCAACGTAGTGCCCGGGCGCCTGACCATGAGCCTGGGCACCTCGGGCACCTT
GTTCGCCTATGCCGATCACCCGGTGGTGGACGATGAGGCGCGCTGGGCCGCGTTCTGCTCCTCCAGCGGCGGCTGGCTGC
CCTTGATCTGCACGATGAACTGCACCGTCGCCACCGAGGCGGTGATGCGCATGTTCTCCATCACCCGCGACCAGACCGAA
GCGATGATCGCCGACACCGCGCCGGGCGCCGACGGGCTGGTGCTGCTGCCGTTCTTCAACGGTGAGCGCACCCCGGATCT
GCCGGCTGCGCGCGGCTGCCTGTTCGGGATGGATCTGCACAACACCACCGCCGCGCATTTCTATCGCGCCGCGATGGAAG
GTGCGACCTACAGCCTGCGCAACGGCTTCGATGCCTTCGTTGCTGCGGGATTGCAGTTCGATACCATCCTGCTCACCGGC
GGCGGCAGCAAGAGCGCGCAGTGGCGGCAGATGGTGGCCGACATCTTCAACCTGCAGGTCGTGGTGCCGACCCAGCCCGA
AGGCGCTGCGTTCGGTGCCGCGCTACAGGCATTGTGGGCCTGCGAGCGCGCCGATGGCGGCGATGCGGCGTTGGCCGACG
TGGTGCTGGAGCACCTGCAGGTGGACGATGCGCTTGCCGCACAGCCCAACCCGCAGCATGTGGCCCAGTATCAGCAGCAC
TATCAGACCTTCCTCAAGCACCTGCATGTCGTCAGCCCGCTCTACGCCGGTTGA

Upstream 100 bases:

>100_bases
GGCGCTATCAACTGTCCTACGCAGGGCAGACCCTGGACCTGGAACTGGGCGCAGGCCGCACCCAGCAGGTGGGACTCAAC
AACAACCGATTGGTGACGCA

Downstream 100 bases:

>100_bases
TCGATAGTTTTTCTACAACTCCCCCAGCAGCAAGGACTTCACACCCCATGAGCAACACCGTGTACATCGGCGCGAAAGAA
TATTTCCCCGGCATCGGCAA

Product: D-xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 497; Mature: 496

Protein sequence:

>497_residues
MSLYVGLDVGTQSVKLVAYDPQDRAVVATIAAPMELISRDDGTREQQAQWWIDGIVHCFAQLDGEQRARVRGISVSGQQH
GFVPVAADGSVTAPVKLWCDTSTALECDEIMAAVGGAAGSVAAAGNPIMAGYTASKLPWTRKHRPDAYAAMTTVMLPHDY
VNFWLTGERFAEVGDASGTGWLDVRTRQWSERMLSAVDAQRDLREALPPLVDTGAVYALSDAAAQALNLPAGVRVTTGGG
DNMMAAIGTGNVVPGRLTMSLGTSGTLFAYADHPVVDDEARWAAFCSSSGGWLPLICTMNCTVATEAVMRMFSITRDQTE
AMIADTAPGADGLVLLPFFNGERTPDLPAARGCLFGMDLHNTTAAHFYRAAMEGATYSLRNGFDAFVAAGLQFDTILLTG
GGSKSAQWRQMVADIFNLQVVVPTQPEGAAFGAALQALWACERADGGDAALADVVLEHLQVDDALAAQPNPQHVAQYQQH
YQTFLKHLHVVSPLYAG

Sequences:

>Translated_497_residues
MSLYVGLDVGTQSVKLVAYDPQDRAVVATIAAPMELISRDDGTREQQAQWWIDGIVHCFAQLDGEQRARVRGISVSGQQH
GFVPVAADGSVTAPVKLWCDTSTALECDEIMAAVGGAAGSVAAAGNPIMAGYTASKLPWTRKHRPDAYAAMTTVMLPHDY
VNFWLTGERFAEVGDASGTGWLDVRTRQWSERMLSAVDAQRDLREALPPLVDTGAVYALSDAAAQALNLPAGVRVTTGGG
DNMMAAIGTGNVVPGRLTMSLGTSGTLFAYADHPVVDDEARWAAFCSSSGGWLPLICTMNCTVATEAVMRMFSITRDQTE
AMIADTAPGADGLVLLPFFNGERTPDLPAARGCLFGMDLHNTTAAHFYRAAMEGATYSLRNGFDAFVAAGLQFDTILLTG
GGSKSAQWRQMVADIFNLQVVVPTQPEGAAFGAALQALWACERADGGDAALADVVLEHLQVDDALAAQPNPQHVAQYQQH
YQTFLKHLHVVSPLYAG
>Mature_496_residues
SLYVGLDVGTQSVKLVAYDPQDRAVVATIAAPMELISRDDGTREQQAQWWIDGIVHCFAQLDGEQRARVRGISVSGQQHG
FVPVAADGSVTAPVKLWCDTSTALECDEIMAAVGGAAGSVAAAGNPIMAGYTASKLPWTRKHRPDAYAAMTTVMLPHDYV
NFWLTGERFAEVGDASGTGWLDVRTRQWSERMLSAVDAQRDLREALPPLVDTGAVYALSDAAAQALNLPAGVRVTTGGGD
NMMAAIGTGNVVPGRLTMSLGTSGTLFAYADHPVVDDEARWAAFCSSSGGWLPLICTMNCTVATEAVMRMFSITRDQTEA
MIADTAPGADGLVLLPFFNGERTPDLPAARGCLFGMDLHNTTAAHFYRAAMEGATYSLRNGFDAFVAAGLQFDTILLTGG
GSKSAQWRQMVADIFNLQVVVPTQPEGAAFGAALQALWACERADGGDAALADVVLEHLQVDDALAAQPNPQHVAQYQQHY
QTFLKHLHVVSPLYAG

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI18860918, Length=511, Percent_Identity=25.440313111546, Blast_Score=108, Evalue=8e-24,
Organism=Escherichia coli, GI1789987, Length=506, Percent_Identity=33.00395256917, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1789168, Length=445, Percent_Identity=27.4157303370787, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787789, Length=323, Percent_Identity=26.625386996904, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1790005, Length=452, Percent_Identity=24.7787610619469, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17554530, Length=533, Percent_Identity=21.7636022514071, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17535599, Length=453, Percent_Identity=21.4128035320088, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356607, Length=472, Percent_Identity=24.1525423728814, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24655555, Length=504, Percent_Identity=21.2301587301587, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655560, Length=504, Percent_Identity=21.2301587301587, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655570, Length=504, Percent_Identity=21.2301587301587, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655574, Length=504, Percent_Identity=21.2301587301587, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655565, Length=504, Percent_Identity=21.2301587301587, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52912; Mature: 52781

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLYVGLDVGTQSVKLVAYDPQDRAVVATIAAPMELISRDDGTREQQAQWWIDGIVHCFA
CEEEEEECCCCCEEEEEEECCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
QLDGEQRARVRGISVSGQQHGFVPVAADGSVTAPVKLWCDTSTALECDEIMAAVGGAAGS
HCCCCHHHEEEEEEECCCCCCEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCC
VAAAGNPIMAGYTASKLPWTRKHRPDAYAAMTTVMLPHDYVNFWLTGERFAEVGDASGTG
HHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHEEECCCCCEEEEECCHHHHHCCCCCCCC
WLDVRTRQWSERMLSAVDAQRDLREALPPLVDTGAVYALSDAAAQALNLPAGVRVTTGGG
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHCCCCCCEEEECCC
DNMMAAIGTGNVVPGRLTMSLGTSGTLFAYADHPVVDDEARWAAFCSSSGGWLPLICTMN
CCEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHEECCCCCEEEEEEEEC
CTVATEAVMRMFSITRDQTEAMIADTAPGADGLVLLPFFNGERTPDLPAARGCLFGMDLH
CHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCC
NTTAAHFYRAAMEGATYSLRNGFDAFVAAGLQFDTILLTGGGSKSAQWRQMVADIFNLQV
CCHHHHHHHHHHCCCCCHHHCCCHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCCEE
VVPTQPEGAAFGAALQALWACERADGGDAALADVVLEHLQVDDALAAQPNPQHVAQYQQH
EEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHH
YQTFLKHLHVVSPLYAG
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLYVGLDVGTQSVKLVAYDPQDRAVVATIAAPMELISRDDGTREQQAQWWIDGIVHCFA
EEEEEECCCCCEEEEEEECCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
QLDGEQRARVRGISVSGQQHGFVPVAADGSVTAPVKLWCDTSTALECDEIMAAVGGAAGS
HCCCCHHHEEEEEEECCCCCCEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCC
VAAAGNPIMAGYTASKLPWTRKHRPDAYAAMTTVMLPHDYVNFWLTGERFAEVGDASGTG
HHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHEEECCCCCEEEEECCHHHHHCCCCCCCC
WLDVRTRQWSERMLSAVDAQRDLREALPPLVDTGAVYALSDAAAQALNLPAGVRVTTGGG
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHCCCCCCEEEECCC
DNMMAAIGTGNVVPGRLTMSLGTSGTLFAYADHPVVDDEARWAAFCSSSGGWLPLICTMN
CCEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHEECCCCCEEEEEEEEC
CTVATEAVMRMFSITRDQTEAMIADTAPGADGLVLLPFFNGERTPDLPAARGCLFGMDLH
CHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCC
NTTAAHFYRAAMEGATYSLRNGFDAFVAAGLQFDTILLTGGGSKSAQWRQMVADIFNLQV
CCHHHHHHHHHHCCCCCHHHCCCHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCCEE
VVPTQPEGAAFGAALQALWACERADGGDAALADVVLEHLQVDDALAAQPNPQHVAQYQQH
EEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHH
YQTFLKHLHVVSPLYAG
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]