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The map label for this gene is mcpA [H]

Identifier: 21242494

GI number: 21242494

Start: 2006029

End: 2008083

Strand: Direct

Name: mcpA [H]

Synonym: XAC1746

Alternate gene names: 21242494

Gene position: 2006029-2008083 (Clockwise)

Preceding gene: 21242493

Following gene: 21242496

Centisome position: 38.76

GC content: 64.62

Gene sequence:

>2055_bases
GTGGTGGGGGGTCAAGTAACCGGCACCTGGGTCGCTAAGGACGTAGACCATATCTCGGATGTTGACGTGATGCGCCTATC
GAACCTGCTTGGACGCGTGTTCTCCTTCTGGGGTCGCGGGCTGCGCCACAAGGTCGCAGCGGTGGACCGGGTGATGGCGG
TCATCGAGTTCGACCTGGACGGCCGCATTCTGGATGCGAACCCGAACTTCCTGGCCCTGATGGGGTATCGACTGGACGAG
GTGATCGGCCAGCACCACCGCATGTTCGTGACGGCCGCAGATCGCGACAGCGAAAGCTATCGGCACTTCTGGGAGGGGCT
GCGGCGCGGAGACTTCAATGCCGGGCGCTTTTGCCGGCTGGATAAACGCGGGCACGAGGTGTGGATCAATGCCTCCTACA
ACCCGTTGCTGGATCGATCCGGCAAGGCGTATCGCGTGGTGAAGTACGCCACCGACATCACTGCGCAGGTACGCCAGACA
GCCGATTTCGAGGGGCGCATCGACGCCATCGACAAGGTGATGGCGGTCATCGAGTTCTCGCTGGACGGCACGGTGCTCGC
GGCCAACCAGAATTTCCTGCAAGTGATGGGCTACCGGCTCGAGGAGATTGTCGGCAAGCATCACCGTATGTTCGTCGATG
CCGGCACGCGCCAGTCGGCGGAGTACCGCGCGTTCTGGGATTCGCTCGGGCGCGGTGCCTTCGATGCAGGCCGCTATCGG
CGCATCGGCAAGGACGGCAGGGAGGTATGGATCCAGGCGTCCTACAACCCGGTGCTCGACGAGCATGGGCGCCCGTACAA
GGTGGTCAAGTATGCCACCGACGTGACCCGCCAGGTGATCGATTCGGCCGATGCGGATGGGCGCATCCGGGCGATCGACA
AGGTCATGGGCGTGGTCGAGTTCGACCTGCAAGGGAACGTGCTCGGTGCGAACGAAAACTTCCTGACCATCATGGGGTAT
CCGGCTGCCGAGGCGATCGGCCAACACCACAGCGTGTTCGTGGATGCGGCCTACCGCGCGTCCGAGGAGTACCGGCAGTT
CTGGGCGAAGCTGGCGAGCGGCCAGTTCGATGCGGGACGTTATCGCCGATTGCGCAAGGATGGCAGTGCGGTGTGGATCC
AGGCTTCCTACAACCCGATCCTGGATGTCTCCGGGCGGCCGTACAAGGTGGTCAAATACGCAACCGACGTCACCGATCAG
GTGCGTTCGGCCGAGCGGATGCGCGATTTGATGCTGCAGACCATGAGCATTGCGCAGAACGTGCAGCGCGAGGCGCATCA
TATTTCAGTGAGCAACCAGGAGCTGGTCAGTCGCGTGTCTACGCAGTCTGCCGCGGTTGCGCAGACCTCGAGCACGATCG
ATCAGCTGGCCGCAACGGTGCGGGCCAATTCCGAGAATGCCGGTTCGGCGCGGCGCATGGCCGAAGACTCGGCCACGGTG
GCGCGGCGCGGTGCCGACGTCATTGCCGATGTGGTCAAGACCACCGCCGGCATTCGCTCGGCGACCGACCGCATCGGTCA
GATCATCGAGGTGATCGACGGCATCGCGTTTCAGACCAACATTCTGGCCCTGAACGCTGCGGTCGAGGCGGCGCGTGCGG
GCGAGCAGGGGCGCGGTTTTGCGGTGGTGGCGACCGAAGTGCGTAGCCTTGCGCAGCGCTGCAGCGTGTCGGCCAGGGAG
ATCCGGTCCTTGATCGACCACGCGACCGATCAGGTCGGCGATGGCTCGCGCCTGGCCGAGCAGGCCGGTGTAGTGATGCA
GGAGATGGTGTCTTCGGTCCTGCGCGTCACTGCGACCGTGGAGCAGATCGCCGCCGCCAGCCATGATCAGGCGCTGGACA
TTTCCAGCGCCAATACCGCGTTGCAGTCGATCGGCGTGCAGGCGCGCGACCAGGCGCAGATGGTGGGCGACTTGGCGCGT
TCGGCGCGCGTGCTGGAAGACGATGCGGATGCGCTGTTCGCCTTGGTCAACGGCGATGCGGATGGCGGGGCGGATCGTGC
GCCAGTGCAGGTCGATGCGCAGGCTGCGCGGCGCGCGACAGCGAAGGTGGCGTGA

Upstream 100 bases:

>100_bases
CGGGCTGCCATGAATGGCACTCAGGACGGGCGTCATTGCCGCTTCGCGAGCACGCGTCGCCTCTGTCCTACACATCTGAA
CCGCCCTGTCGATGCGGCAT

Downstream 100 bases:

>100_bases
TGATGGTTGACTGCGTCCCGCACGCGAGATCGTGATGTTCCCTTAGATCCTGCACTTCCTTGTAGTGGATCTCGGCGCAA
GTGGCCGAACCTGCGGTGCT

Product: chemotaxis protein

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 684; Mature: 684

Protein sequence:

>684_residues
MVGGQVTGTWVAKDVDHISDVDVMRLSNLLGRVFSFWGRGLRHKVAAVDRVMAVIEFDLDGRILDANPNFLALMGYRLDE
VIGQHHRMFVTAADRDSESYRHFWEGLRRGDFNAGRFCRLDKRGHEVWINASYNPLLDRSGKAYRVVKYATDITAQVRQT
ADFEGRIDAIDKVMAVIEFSLDGTVLAANQNFLQVMGYRLEEIVGKHHRMFVDAGTRQSAEYRAFWDSLGRGAFDAGRYR
RIGKDGREVWIQASYNPVLDEHGRPYKVVKYATDVTRQVIDSADADGRIRAIDKVMGVVEFDLQGNVLGANENFLTIMGY
PAAEAIGQHHSVFVDAAYRASEEYRQFWAKLASGQFDAGRYRRLRKDGSAVWIQASYNPILDVSGRPYKVVKYATDVTDQ
VRSAERMRDLMLQTMSIAQNVQREAHHISVSNQELVSRVSTQSAAVAQTSSTIDQLAATVRANSENAGSARRMAEDSATV
ARRGADVIADVVKTTAGIRSATDRIGQIIEVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVATEVRSLAQRCSVSARE
IRSLIDHATDQVGDGSRLAEQAGVVMQEMVSSVLRVTATVEQIAAASHDQALDISSANTALQSIGVQARDQAQMVGDLAR
SARVLEDDADALFALVNGDADGGADRAPVQVDAQAARRATAKVA

Sequences:

>Translated_684_residues
MVGGQVTGTWVAKDVDHISDVDVMRLSNLLGRVFSFWGRGLRHKVAAVDRVMAVIEFDLDGRILDANPNFLALMGYRLDE
VIGQHHRMFVTAADRDSESYRHFWEGLRRGDFNAGRFCRLDKRGHEVWINASYNPLLDRSGKAYRVVKYATDITAQVRQT
ADFEGRIDAIDKVMAVIEFSLDGTVLAANQNFLQVMGYRLEEIVGKHHRMFVDAGTRQSAEYRAFWDSLGRGAFDAGRYR
RIGKDGREVWIQASYNPVLDEHGRPYKVVKYATDVTRQVIDSADADGRIRAIDKVMGVVEFDLQGNVLGANENFLTIMGY
PAAEAIGQHHSVFVDAAYRASEEYRQFWAKLASGQFDAGRYRRLRKDGSAVWIQASYNPILDVSGRPYKVVKYATDVTDQ
VRSAERMRDLMLQTMSIAQNVQREAHHISVSNQELVSRVSTQSAAVAQTSSTIDQLAATVRANSENAGSARRMAEDSATV
ARRGADVIADVVKTTAGIRSATDRIGQIIEVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVATEVRSLAQRCSVSARE
IRSLIDHATDQVGDGSRLAEQAGVVMQEMVSSVLRVTATVEQIAAASHDQALDISSANTALQSIGVQARDQAQMVGDLAR
SARVLEDDADALFALVNGDADGGADRAPVQVDAQAARRATAKVA
>Mature_684_residues
MVGGQVTGTWVAKDVDHISDVDVMRLSNLLGRVFSFWGRGLRHKVAAVDRVMAVIEFDLDGRILDANPNFLALMGYRLDE
VIGQHHRMFVTAADRDSESYRHFWEGLRRGDFNAGRFCRLDKRGHEVWINASYNPLLDRSGKAYRVVKYATDITAQVRQT
ADFEGRIDAIDKVMAVIEFSLDGTVLAANQNFLQVMGYRLEEIVGKHHRMFVDAGTRQSAEYRAFWDSLGRGAFDAGRYR
RIGKDGREVWIQASYNPVLDEHGRPYKVVKYATDVTRQVIDSADADGRIRAIDKVMGVVEFDLQGNVLGANENFLTIMGY
PAAEAIGQHHSVFVDAAYRASEEYRQFWAKLASGQFDAGRYRRLRKDGSAVWIQASYNPILDVSGRPYKVVKYATDVTDQ
VRSAERMRDLMLQTMSIAQNVQREAHHISVSNQELVSRVSTQSAAVAQTSSTIDQLAATVRANSENAGSARRMAEDSATV
ARRGADVIADVVKTTAGIRSATDRIGQIIEVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVATEVRSLAQRCSVSARE
IRSLIDHATDQVGDGSRLAEQAGVVMQEMVSSVLRVTATVEQIAAASHDQALDISSANTALQSIGVQARDQAQMVGDLAR
SARVLEDDADALFALVNGDADGGADRAPVQVDAQAARRATAKVA

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=187, Percent_Identity=52.9411764705882, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1788194, Length=272, Percent_Identity=40.8088235294118, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI1788195, Length=185, Percent_Identity=49.7297297297297, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1787690, Length=232, Percent_Identity=42.2413793103448, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1789453, Length=207, Percent_Identity=42.512077294686, Blast_Score=149, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 75033; Mature: 75033

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGGQVTGTWVAKDVDHISDVDVMRLSNLLGRVFSFWGRGLRHKVAAVDRVMAVIEFDLD
CCCCCEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCC
GRILDANPNFLALMGYRLDEVIGQHHRMFVTAADRDSESYRHFWEGLRRGDFNAGRFCRL
CEEEECCCCEEEEECHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEE
DKRGHEVWINASYNPLLDRSGKAYRVVKYATDITAQVRQTADFEGRIDAIDKVMAVIEFS
ECCCCEEEEECCCCCHHCCCCCEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
LDGTVLAANQNFLQVMGYRLEEIVGKHHRMFVDAGTRQSAEYRAFWDSLGRGAFDAGRYR
CCCEEEECCCHHHHHHHHHHHHHHCCHHEEEEECCCCCCCHHHHHHHHHCCCCCCCHHHH
RIGKDGREVWIQASYNPVLDEHGRPYKVVKYATDVTRQVIDSADADGRIRAIDKVMGVVE
HCCCCCCEEEEEECCCCHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEE
FDLQGNVLGANENFLTIMGYPAAEAIGQHHSVFVDAAYRASEEYRQFWAKLASGQFDAGR
ECCCCCEEECCCCEEEEECCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHH
YRRLRKDGSAVWIQASYNPILDVSGRPYKVVKYATDVTDQVRSAERMRDLMLQTMSIAQN
HHHHHCCCCEEEEEECCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQREAHHISVSNQELVSRVSTQSAAVAQTSSTIDQLAATVRANSENAGSARRMAEDSATV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ARRGADVIADVVKTTAGIRSATDRIGQIIEVIDGIAFQTNILALNAAVEAARAGEQGRGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEHHHHHHHHCCCCCCCE
AVVATEVRSLAQRCSVSAREIRSLIDHATDQVGDGSRLAEQAGVVMQEMVSSVLRVTATV
EEEHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EQIAAASHDQALDISSANTALQSIGVQARDQAQMVGDLARSARVLEDDADALFALVNGDA
HHHHHCCCCCCEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
DGGADRAPVQVDAQAARRATAKVA
CCCCCCCCEEECHHHHHHHHHCCC
>Mature Secondary Structure
MVGGQVTGTWVAKDVDHISDVDVMRLSNLLGRVFSFWGRGLRHKVAAVDRVMAVIEFDLD
CCCCCEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCC
GRILDANPNFLALMGYRLDEVIGQHHRMFVTAADRDSESYRHFWEGLRRGDFNAGRFCRL
CEEEECCCCEEEEECHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEE
DKRGHEVWINASYNPLLDRSGKAYRVVKYATDITAQVRQTADFEGRIDAIDKVMAVIEFS
ECCCCEEEEECCCCCHHCCCCCEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
LDGTVLAANQNFLQVMGYRLEEIVGKHHRMFVDAGTRQSAEYRAFWDSLGRGAFDAGRYR
CCCEEEECCCHHHHHHHHHHHHHHCCHHEEEEECCCCCCCHHHHHHHHHCCCCCCCHHHH
RIGKDGREVWIQASYNPVLDEHGRPYKVVKYATDVTRQVIDSADADGRIRAIDKVMGVVE
HCCCCCCEEEEEECCCCHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEE
FDLQGNVLGANENFLTIMGYPAAEAIGQHHSVFVDAAYRASEEYRQFWAKLASGQFDAGR
ECCCCCEEECCCCEEEEECCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHH
YRRLRKDGSAVWIQASYNPILDVSGRPYKVVKYATDVTDQVRSAERMRDLMLQTMSIAQN
HHHHHCCCCEEEEEECCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQREAHHISVSNQELVSRVSTQSAAVAQTSSTIDQLAATVRANSENAGSARRMAEDSATV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ARRGADVIADVVKTTAGIRSATDRIGQIIEVIDGIAFQTNILALNAAVEAARAGEQGRGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEHHHHHHHHCCCCCCCE
AVVATEVRSLAQRCSVSAREIRSLIDHATDQVGDGSRLAEQAGVVMQEMVSSVLRVTATV
EEEHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EQIAAASHDQALDISSANTALQSIGVQARDQAQMVGDLARSARVLEDDADALFALVNGDA
HHHHHCCCCCCEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
DGGADRAPVQVDAQAARRATAKVA
CCCCCCCCEEECHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]