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The map label for this gene is gpo [H]

Identifier: 21242209

GI number: 21242209

Start: 1683087

End: 1683572

Strand: Direct

Name: gpo [H]

Synonym: XAC1457

Alternate gene names: 21242209

Gene position: 1683087-1683572 (Clockwise)

Preceding gene: 21242207

Following gene: 21242212

Centisome position: 32.52

GC content: 62.35

Gene sequence:

>486_bases
ATGAGCGACATCTCCACCTTCGCATTCACCGACCTGGAAGGTCGCACCCAGTCGATGCGCGATTATGCCGGCAACGTACT
GCTGGTGGTCAATGTCGCCTCCAAGTGCGGGTTTACGCCGCAATACGCGGGGCTGCAGGCCCTGTGGCAGCGTTATCGCG
AACGTGGACTGGTAGTGATCGGTTTTCCATGCGATCAGTTCGGGCACCAGGAGCCGGGCGATGCGGCGCAGATCCGCCAG
TTCTGCTCGCTCGACTATGCGGTGGATTTTCCGCTGGCCGCGAAAATCGACGTCAACGGCAACGGCGCGCATCCGCTGTG
GCAATGGCTCAAGCACGAACAACGCGGCGTGCTCGGGTCCGAGGCGATCAAGTGGAACTTCACCAAGTTCCTGATCGGCC
GCGACGGCCGCGTGCTGGAACGTTATGCGCCCACCACCAAGCCGGAGGCATTGGCTACCGAGATCGAGCGCGCGCTGGAC
GCATGA

Upstream 100 bases:

>100_bases
GATCTGTCGCACGACTGACCTCTGCCATCCTTCTTCCGCCGCGTGGCCGCCGTGCAGGCGGCTACGGTACGCTGCCCGTC
TCGCACATTGCAGGGCAACC

Downstream 100 bases:

>100_bases
TCCGGCAGGGCGTGGTGCTGGAATCGTAGGGGCGCACCCGGGCGCGACGAGGCGTTACCGGGAACGCTTCGTTGCGCCCG
GGGGCGCTCCTACGACAGCG

Product: glutathione peroxidase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSDISTFAFTDLEGRTQSMRDYAGNVLLVVNVASKCGFTPQYAGLQALWQRYRERGLVVIGFPCDQFGHQEPGDAAQIRQ
FCSLDYAVDFPLAAKIDVNGNGAHPLWQWLKHEQRGVLGSEAIKWNFTKFLIGRDGRVLERYAPTTKPEALATEIERALD
A

Sequences:

>Translated_161_residues
MSDISTFAFTDLEGRTQSMRDYAGNVLLVVNVASKCGFTPQYAGLQALWQRYRERGLVVIGFPCDQFGHQEPGDAAQIRQ
FCSLDYAVDFPLAAKIDVNGNGAHPLWQWLKHEQRGVLGSEAIKWNFTKFLIGRDGRVLERYAPTTKPEALATEIERALD
A
>Mature_160_residues
SDISTFAFTDLEGRTQSMRDYAGNVLLVVNVASKCGFTPQYAGLQALWQRYRERGLVVIGFPCDQFGHQEPGDAAQIRQF
CSLDYAVDFPLAAKIDVNGNGAHPLWQWLKHEQRGVLGSEAIKWNFTKFLIGRDGRVLERYAPTTKPEALATEIERALDA

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=43.8709677419355, Blast_Score=131, Evalue=3e-31,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=43.8709677419355, Blast_Score=130, Evalue=4e-31,
Organism=Homo sapiens, GI15618997, Length=154, Percent_Identity=40.2597402597403, Blast_Score=114, Evalue=3e-26,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=45.8015267175573, Blast_Score=111, Evalue=3e-25,
Organism=Homo sapiens, GI192455698, Length=156, Percent_Identity=32.6923076923077, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI4557629, Length=159, Percent_Identity=37.7358490566038, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI6006001, Length=158, Percent_Identity=36.0759493670886, Blast_Score=87, Evalue=6e-18,
Organism=Homo sapiens, GI41406084, Length=168, Percent_Identity=36.9047619047619, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI33186887, Length=137, Percent_Identity=35.7664233576642, Blast_Score=81, Evalue=4e-16,
Organism=Homo sapiens, GI32967607, Length=174, Percent_Identity=32.7586206896552, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788003, Length=165, Percent_Identity=42.4242424242424, Blast_Score=150, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=43.75, Blast_Score=146, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17535473, Length=162, Percent_Identity=43.2098765432099, Blast_Score=144, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI193210707, Length=162, Percent_Identity=43.8271604938272, Blast_Score=133, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71993584, Length=159, Percent_Identity=40.8805031446541, Blast_Score=125, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17550320, Length=165, Percent_Identity=31.5151515151515, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=30.6748466257669, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=50.9433962264151, Blast_Score=185, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6319721, Length=159, Percent_Identity=48.4276729559748, Blast_Score=176, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322826, Length=160, Percent_Identity=40, Blast_Score=142, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24656777, Length=161, Percent_Identity=47.8260869565217, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24656767, Length=161, Percent_Identity=47.8260869565217, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24656772, Length=161, Percent_Identity=47.8260869565217, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI85726443, Length=158, Percent_Identity=39.873417721519, Blast_Score=109, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18038; Mature: 17906

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDISTFAFTDLEGRTQSMRDYAGNVLLVVNVASKCGFTPQYAGLQALWQRYRERGLVVI
CCCCCCEEEECCCCCHHHHHHHCCCEEEEEEEHHHCCCCCCHHHHHHHHHHHHHCCEEEE
GFPCDQFGHQEPGDAAQIRQFCSLDYAVDFPLAAKIDVNGNGAHPLWQWLKHEQRGVLGS
ECCCHHHCCCCCCCHHHHHHHHCCCCEECCCEEEEEEECCCCCCHHHHHHHHHHCCCCCC
EAIKWNFTKFLIGRDGRVLERYAPTTKPEALATEIERALDA
CCEEECCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDISTFAFTDLEGRTQSMRDYAGNVLLVVNVASKCGFTPQYAGLQALWQRYRERGLVVI
CCCCCEEEECCCCCHHHHHHHCCCEEEEEEEHHHCCCCCCHHHHHHHHHHHHHCCEEEE
GFPCDQFGHQEPGDAAQIRQFCSLDYAVDFPLAAKIDVNGNGAHPLWQWLKHEQRGVLGS
ECCCHHHCCCCCCCHHHHHHHHCCCCEECCCEEEEEEECCCCCCHHHHHHHHHHCCCCCC
EAIKWNFTKFLIGRDGRVLERYAPTTKPEALATEIERALDA
CCEEECCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]