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The map label for this gene is mprA [H]

Identifier: 21242207

GI number: 21242207

Start: 1679787

End: 1680287

Strand: Direct

Name: mprA [H]

Synonym: XAC1455

Alternate gene names: 21242207

Gene position: 1679787-1680287 (Clockwise)

Preceding gene: 21242206

Following gene: 21242209

Centisome position: 32.46

GC content: 60.08

Gene sequence:

>501_bases
ATGAGTAGTTTCGATCCGACCGCAAGTCGCGTGGACCACACCTGCGTGCGTTATCCGGCGTTCCCACGGGAGCCGGCAAT
ATTGGTGAGACTGATCAAGCATCTCTACAAGCGCCTGCATACGCTCGGGTGCGTGCGGCTCAAGCCTTATGGCATCAGTC
CGCCGGAATACGAGATCTTGATGATGCTCTATGGCACACCGGAGCAGTCGATCACTCCGACCGAGGTGGCCGAAGCCGCC
AGCGAAAAGCCGGCCAACATCACCCGGCTCACCGATCAGCTGTGCGAGAAAGGCCTGATCACGCGCACCAGCAGCCCCGA
AGATCGGCGCAAGATCGTACTGACGCTGCAACCGGCAGGCTCGGCCTTGATCGAAAGCCTGTTGCCCGATGCCTGCACGC
TGTTGCATGCAGAGACCGCCAGTATGAGCGAGGCCGAGCAGCTACGGTTGGAGAAGCTGCTGAAAAAGCTTCTGGATGGC
GTGGACGCGGTCGAACTCTGA

Upstream 100 bases:

>100_bases
TCGCACCGGAATATGTACATCTCTTCGCGCGCTGAGGTGTCGCATCGCGCATGTTGTGATTGAATGGCCCGGCCATTCAG
CAATGTACTCGACGGGTGAT

Downstream 100 bases:

>100_bases
GCGGCGCGCGTTGCGCGTGCGATAAGCGCTGCAAACGCAGCACGCAAAAAAACCGCCCTGGTCGCCCAGGGCGGCGTTGT
CATCTCATCGGTTCTCAAGC

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: Protein emrR [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MSSFDPTASRVDHTCVRYPAFPREPAILVRLIKHLYKRLHTLGCVRLKPYGISPPEYEILMMLYGTPEQSITPTEVAEAA
SEKPANITRLTDQLCEKGLITRTSSPEDRRKIVLTLQPAGSALIESLLPDACTLLHAETASMSEAEQLRLEKLLKKLLDG
VDAVEL

Sequences:

>Translated_166_residues
MSSFDPTASRVDHTCVRYPAFPREPAILVRLIKHLYKRLHTLGCVRLKPYGISPPEYEILMMLYGTPEQSITPTEVAEAA
SEKPANITRLTDQLCEKGLITRTSSPEDRRKIVLTLQPAGSALIESLLPDACTLLHAETASMSEAEQLRLEKLLKKLLDG
VDAVEL
>Mature_165_residues
SSFDPTASRVDHTCVRYPAFPREPAILVRLIKHLYKRLHTLGCVRLKPYGISPPEYEILMMLYGTPEQSITPTEVAEAAS
EKPANITRLTDQLCEKGLITRTSSPEDRRKIVLTLQPAGSALIESLLPDACTLLHAETASMSEAEQLRLEKLLKKLLDGV
DAVEL

Specific function: Negative regulator of the multidrug operon emrAB [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789040, Length=164, Percent_Identity=31.0975609756098, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 18455; Mature: 18323

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFDPTASRVDHTCVRYPAFPREPAILVRLIKHLYKRLHTLGCVRLKPYGISPPEYEIL
CCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEEE
MMLYGTPEQSITPTEVAEAASEKPANITRLTDQLCEKGLITRTSSPEDRRKIVLTLQPAG
EEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCC
SALIESLLPDACTLLHAETASMSEAEQLRLEKLLKKLLDGVDAVEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSFDPTASRVDHTCVRYPAFPREPAILVRLIKHLYKRLHTLGCVRLKPYGISPPEYEIL
CCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEEE
MMLYGTPEQSITPTEVAEAASEKPANITRLTDQLCEKGLITRTSSPEDRRKIVLTLQPAG
EEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCC
SALIESLLPDACTLLHAETASMSEAEQLRLEKLLKKLLDGVDAVEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]