Click here to switch to the map view.

The map label for this gene is mucD [H]

Identifier: 21242074

GI number: 21242074

Start: 1525685

End: 1527262

Strand: Direct

Name: mucD [H]

Synonym: XAC1321

Alternate gene names: 21242074

Gene position: 1525685-1527262 (Clockwise)

Preceding gene: 21242073

Following gene: 21242075

Centisome position: 29.48

GC content: 68.57

Gene sequence:

>1578_bases
ATGAACCATCGCATCCGCACCCAGATGTTCGGCCTGATCGCCATGACCCTGCCGCTGGCCGCCTGCGCGCAGCAGCCCGC
ACCCGCTGCCAAGGACCTCGCCCCGATTGCTGCCAATCGCAGTGCAACGCCAGCGCCGCAGCTGGTGGCGGGGCTGCCGG
ACTTCACCAATCTGGTCGAGCAGGTCGGCCCGGGTGTGGTCAATATCGAAACCACCATTACCCGCAAGGATGCCATGGCG
CGTCAGCAGCGCAGTGGCCCGGGTGGTCGTGGCGGTGGTGCGATGCCGGATGACGATCAGATGCCGGAATTCTTCCGCCG
CTTTTTCGGGCCGGACTTCCAGATGCCGGGCGGTCCGCGGCAGGGGCCCGGTGGCGGCGATGACGACGGCGGCATCGCCG
GCAAGTCGATGGGCTCGGGCTTCATCATCTCGGCCGACGGCTACGTCCTGACCAATCATCACGTGGTCGATGGCGCCAGC
GAGGTGACCGTCAAGCTCACCGACCGCCGCGAGTTCAAGGCCAAGGTGGTGGGTAGCGACGAGCAATACGACGTGGCGCT
GCTGAAGATCGAGGCCAAGGGCCTGCCGACCGTGCGCCTGGGCGATTCCAACACGCTCAAGCCGGGGCAGTGGGTGGTGG
CGATCGGCTCGCCGTTCGGCCTGGATCACTCGGTCACCGCCGGCATCGTCAGCGCCACCGGCCGCAGCAATCCGTACGCC
GACCAGCGCTACGTGCCCTTCATCCAGACCGACGTGGCGATCAACCAGGGTAATTCCGGCGGCCCGCTGCTCAATACGCG
TGGCGAAGTGGTCGGCATCAATTCGCAGATCTTCTCCGCGTCCGGCGGCTACATGGGCATCAGTTTCGCGATCCCGATCG
ACCTGGCCTTCAGCGCGGCCGAGCAGATCAAGGCCACCGGCCACGTGAGTCGCGGCATGCTGGGCGTGGCGGTCGGCCCG
ATCGACTCGCTCAAGGCGCAAGGCCTGGGCTTGCCGGATAGCCGTGGTGCCCTGGTCAACGATATCCCGGCCGGTAGCCC
GGCGGCCAAGGCCGGCATCGAGGTGGGCGATGTGATCCGGGCGGTGAACGGCAAGTCGATCGATGTCGCCAGCGATCTGC
CGCCAATGATCGGGCTGATGGCGCCTGGTACCAAGGTGACCCTGGACGTCTTGCGCGACGGCAAGCCGCGCACCGTGACG
GTCACCCTGGCACCGTTGCAGGACGGCACCGGGAACGCCGCGCCGCGCACCGCCGCCGAGGAGGCCAAGCCCGGCGCGCC
GGCCAGCGTGGAGTTGCTCGGCCTGCAAGTCGCCGACCTGACCGCCGCCGAACGCAGCCGCCTGGGCCTGGAAGTGGGCG
AGGGTGTGCGTATTGCCGCGGTCACGGGCGCGGCGGCACGCAGCACCCAGCCGCCGCTGTCGCCGGGGCTGATCATCGCC
CGCGTGGGCCGGACCAAGGTCGGCAGCGTCGCCGAGCTCAACCGCGCCCTGTCCAGCTACAAGAAGGGCGACGTGGTCAT
GCTGCTGGTGACCGACGGCAAGGCGACCAGCTACGTGGCCTTGAAGGCCGGCGGCTAA

Upstream 100 bases:

>100_bases
CGGCCTTCATCCGTTCGGCTATCTCCCTCCCATTATCGTGCCGGGCCCGTGTTGCTACGCGGGTTCTGGCTCCTGTCGCC
CTGCCATCGGAGGCAACCTG

Downstream 100 bases:

>100_bases
CGCAGGGAATGGAGAATCGGGAATCGGGAATGGCAAGAGCGGCTCCGCGATACGGGAGCACGCCTGGCTTTTCCGATTCC
CCACTCCCGATTCCCAATTC

Product: periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MNHRIRTQMFGLIAMTLPLAACAQQPAPAAKDLAPIAANRSATPAPQLVAGLPDFTNLVEQVGPGVVNIETTITRKDAMA
RQQRSGPGGRGGGAMPDDDQMPEFFRRFFGPDFQMPGGPRQGPGGGDDDGGIAGKSMGSGFIISADGYVLTNHHVVDGAS
EVTVKLTDRREFKAKVVGSDEQYDVALLKIEAKGLPTVRLGDSNTLKPGQWVVAIGSPFGLDHSVTAGIVSATGRSNPYA
DQRYVPFIQTDVAINQGNSGGPLLNTRGEVVGINSQIFSASGGYMGISFAIPIDLAFSAAEQIKATGHVSRGMLGVAVGP
IDSLKAQGLGLPDSRGALVNDIPAGSPAAKAGIEVGDVIRAVNGKSIDVASDLPPMIGLMAPGTKVTLDVLRDGKPRTVT
VTLAPLQDGTGNAAPRTAAEEAKPGAPASVELLGLQVADLTAAERSRLGLEVGEGVRIAAVTGAAARSTQPPLSPGLIIA
RVGRTKVGSVAELNRALSSYKKGDVVMLLVTDGKATSYVALKAGG

Sequences:

>Translated_525_residues
MNHRIRTQMFGLIAMTLPLAACAQQPAPAAKDLAPIAANRSATPAPQLVAGLPDFTNLVEQVGPGVVNIETTITRKDAMA
RQQRSGPGGRGGGAMPDDDQMPEFFRRFFGPDFQMPGGPRQGPGGGDDDGGIAGKSMGSGFIISADGYVLTNHHVVDGAS
EVTVKLTDRREFKAKVVGSDEQYDVALLKIEAKGLPTVRLGDSNTLKPGQWVVAIGSPFGLDHSVTAGIVSATGRSNPYA
DQRYVPFIQTDVAINQGNSGGPLLNTRGEVVGINSQIFSASGGYMGISFAIPIDLAFSAAEQIKATGHVSRGMLGVAVGP
IDSLKAQGLGLPDSRGALVNDIPAGSPAAKAGIEVGDVIRAVNGKSIDVASDLPPMIGLMAPGTKVTLDVLRDGKPRTVT
VTLAPLQDGTGNAAPRTAAEEAKPGAPASVELLGLQVADLTAAERSRLGLEVGEGVRIAAVTGAAARSTQPPLSPGLIIA
RVGRTKVGSVAELNRALSSYKKGDVVMLLVTDGKATSYVALKAGG
>Mature_525_residues
MNHRIRTQMFGLIAMTLPLAACAQQPAPAAKDLAPIAANRSATPAPQLVAGLPDFTNLVEQVGPGVVNIETTITRKDAMA
RQQRSGPGGRGGGAMPDDDQMPEFFRRFFGPDFQMPGGPRQGPGGGDDDGGIAGKSMGSGFIISADGYVLTNHHVVDGAS
EVTVKLTDRREFKAKVVGSDEQYDVALLKIEAKGLPTVRLGDSNTLKPGQWVVAIGSPFGLDHSVTAGIVSATGRSNPYA
DQRYVPFIQTDVAINQGNSGGPLLNTRGEVVGINSQIFSASGGYMGISFAIPIDLAFSAAEQIKATGHVSRGMLGVAVGP
IDSLKAQGLGLPDSRGALVNDIPAGSPAAKAGIEVGDVIRAVNGKSIDVASDLPPMIGLMAPGTKVTLDVLRDGKPRTVT
VTLAPLQDGTGNAAPRTAAEEAKPGAPASVELLGLQVADLTAAERSRLGLEVGEGVRIAAVTGAAARSTQPPLSPGLIIA
RVGRTKVGSVAELNRALSSYKKGDVVMLLVTDGKATSYVALKAGG

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=254, Percent_Identity=41.7322834645669, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI22129776, Length=255, Percent_Identity=40, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI24308541, Length=250, Percent_Identity=37.6, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI7019477, Length=255, Percent_Identity=38.4313725490196, Blast_Score=139, Evalue=8e-33,
Organism=Escherichia coli, GI1789629, Length=520, Percent_Identity=34.0384615384615, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1786356, Length=500, Percent_Identity=36.2, Blast_Score=247, Evalue=2e-66,
Organism=Escherichia coli, GI1789630, Length=275, Percent_Identity=40.7272727272727, Blast_Score=182, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24646839, Length=289, Percent_Identity=39.4463667820069, Blast_Score=168, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 53854; Mature: 53854

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHRIRTQMFGLIAMTLPLAACAQQPAPAAKDLAPIAANRSATPAPQLVAGLPDFTNLVE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHCCCCCCCCHHHHHCCCHHHHHHH
QVGPGVVNIETTITRKDAMARQQRSGPGGRGGGAMPDDDQMPEFFRRFFGPDFQMPGGPR
HHCCCEEEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
QGPGGGDDDGGIAGKSMGSGFIISADGYVLTNHHVVDGASEVTVKLTDRREFKAKVVGSD
CCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCC
EQYDVALLKIEAKGLPTVRLGDSNTLKPGQWVVAIGSPFGLDHSVTAGIVSATGRSNPYA
CCEEEEEEEEECCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHEEECCCCCCCCC
DQRYVPFIQTDVAINQGNSGGPLLNTRGEVVGINSQIFSASGGYMGISFAIPIDLAFSAA
CCCCCCEEEEEEEEECCCCCCCEECCCCCEEEECCEEEECCCCEEEEEEEEEEHHHHHHH
EQIKATGHVSRGMLGVAVGPIDSLKAQGLGLPDSRGALVNDIPAGSPAAKAGIEVGDVIR
HHHHHHCCHHCCEEEEEECCHHHHHHCCCCCCCCCCCEEECCCCCCCHHHCCCCHHHHHH
AVNGKSIDVASDLPPMIGLMAPGTKVTLDVLRDGKPRTVTVTLAPLQDGTGNAAPRTAAE
HCCCCEEEECCCCCCHHEEECCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCHH
EAKPGAPASVELLGLQVADLTAAERSRLGLEVGEGVRIAAVTGAAARSTQPPLSPGLIIA
HCCCCCCCEEEEEEEEEEHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEE
RVGRTKVGSVAELNRALSSYKKGDVVMLLVTDGKATSYVALKAGG
ECCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEEECC
>Mature Secondary Structure
MNHRIRTQMFGLIAMTLPLAACAQQPAPAAKDLAPIAANRSATPAPQLVAGLPDFTNLVE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHCCCCCCCCHHHHHCCCHHHHHHH
QVGPGVVNIETTITRKDAMARQQRSGPGGRGGGAMPDDDQMPEFFRRFFGPDFQMPGGPR
HHCCCEEEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
QGPGGGDDDGGIAGKSMGSGFIISADGYVLTNHHVVDGASEVTVKLTDRREFKAKVVGSD
CCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCC
EQYDVALLKIEAKGLPTVRLGDSNTLKPGQWVVAIGSPFGLDHSVTAGIVSATGRSNPYA
CCEEEEEEEEECCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHEEECCCCCCCCC
DQRYVPFIQTDVAINQGNSGGPLLNTRGEVVGINSQIFSASGGYMGISFAIPIDLAFSAA
CCCCCCEEEEEEEEECCCCCCCEECCCCCEEEECCEEEECCCCEEEEEEEEEEHHHHHHH
EQIKATGHVSRGMLGVAVGPIDSLKAQGLGLPDSRGALVNDIPAGSPAAKAGIEVGDVIR
HHHHHHCCHHCCEEEEEECCHHHHHHCCCCCCCCCCCEEECCCCCCCHHHCCCCHHHHHH
AVNGKSIDVASDLPPMIGLMAPGTKVTLDVLRDGKPRTVTVTLAPLQDGTGNAAPRTAAE
HCCCCEEEECCCCCCHHEEECCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCHH
EAKPGAPASVELLGLQVADLTAAERSRLGLEVGEGVRIAAVTGAAARSTQPPLSPGLIIA
HCCCCCCCEEEEEEEEEEHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEE
RVGRTKVGSVAELNRALSSYKKGDVVMLLVTDGKATSYVALKAGG
ECCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]