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The map label for this gene is yfjP [H]

Identifier: 21241986

GI number: 21241986

Start: 1410326

End: 1410973

Strand: Direct

Name: yfjP [H]

Synonym: XAC1232

Alternate gene names: 21241986

Gene position: 1410326-1410973 (Clockwise)

Preceding gene: 21241985

Following gene: 21241991

Centisome position: 27.25

GC content: 67.59

Gene sequence:

>648_bases
GTGGAGGCTGCGTTCGCGCACGTGTCCCGGCGCGATCGCGCGCTGGGTGCGTGGATGAAGCGCATCGGCCCGATCGCCCC
GCAACCGGGGTGGCACAAACCCTTCGACCCGGTGGATGCGCTGGCACGCGCCATCCTGTTTCAGCAACTCAGCGGCAAGG
CGGCTTCGACCATCGTGGCGCGTGTGGAAGTGGCGATCGGCGCGCAGCGGCTCCATGCGGACACCCTCGGTCGTATCGAC
GATGCGGCGCTGCGTGCCTGCGGCGTTTCGGGTAACAAGGCGCTGGCCCTGCGCGATCTGGCACGCCGCGAAAGCGAAGG
CGAGATTCCCTCGCTGCGCAGGCTTGCCTTCATGGACGAGGAAGCCATCGTGCAGGCACTGGTGCCGGTGCGCGGCATCG
GCCGCTGGACCGTGGAAATGATGCTGATGTTCCGCCTGGGCCGCCCGGATCTGCTGCCCATCGACGACCTGGGCGTGCGC
AAAGGGGCGCAGCGCGTGGACAAGCAGGAGCAGATGCCCACCCCCAAGGAACTGGCCGTACGCGGTGAACGCTGGGGCCC
GTACCGCACCTATGCCGCGTTCTATCTGTGGAAGATTGCCGACTTCAGCGTGGCGACCAAGGTGCCGACACCGCGTTCGC
AGGAGTAG

Upstream 100 bases:

>100_bases
TGGCGCCGGTCGGCGGAGTTGGGCTGATGCTGGGCTGGGTGGTGCTGGCCATTGGTGCGTTGAGGCGCTGAGCATGCCGC
GCCATGCCCGCGGATTCGAT

Downstream 100 bases:

>100_bases
GACGCTCGCACGCGGGGCAGATGCGACGGGCGGTCGGGTCCAGCCGGGTTGCGTGGCGCATGAAGTTCGGCCGGCTCATC
CCGCCGACCAACACCAATGC

Product: DNA-3-methyladenine glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MEAAFAHVSRRDRALGAWMKRIGPIAPQPGWHKPFDPVDALARAILFQQLSGKAASTIVARVEVAIGAQRLHADTLGRID
DAALRACGVSGNKALALRDLARRESEGEIPSLRRLAFMDEEAIVQALVPVRGIGRWTVEMMLMFRLGRPDLLPIDDLGVR
KGAQRVDKQEQMPTPKELAVRGERWGPYRTYAAFYLWKIADFSVATKVPTPRSQE

Sequences:

>Translated_215_residues
MEAAFAHVSRRDRALGAWMKRIGPIAPQPGWHKPFDPVDALARAILFQQLSGKAASTIVARVEVAIGAQRLHADTLGRID
DAALRACGVSGNKALALRDLARRESEGEIPSLRRLAFMDEEAIVQALVPVRGIGRWTVEMMLMFRLGRPDLLPIDDLGVR
KGAQRVDKQEQMPTPKELAVRGERWGPYRTYAAFYLWKIADFSVATKVPTPRSQE
>Mature_215_residues
MEAAFAHVSRRDRALGAWMKRIGPIAPQPGWHKPFDPVDALARAILFQQLSGKAASTIVARVEVAIGAQRLHADTLGRID
DAALRACGVSGNKALALRDLARRESEGEIPSLRRLAFMDEEAIVQALVPVRGIGRWTVEMMLMFRLGRPDLLPIDDLGVR
KGAQRVDKQEQMPTPKELAVRGERWGPYRTYAAFYLWKIADFSVATKVPTPRSQE

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320990, Length=182, Percent_Identity=32.4175824175824, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 23921; Mature: 23921

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAAFAHVSRRDRALGAWMKRIGPIAPQPGWHKPFDPVDALARAILFQQLSGKAASTIVA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
RVEVAIGAQRLHADTLGRIDDAALRACGVSGNKALALRDLARRESEGEIPSLRRLAFMDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCH
EAIVQALVPVRGIGRWTVEMMLMFRLGRPDLLPIDDLGVRKGAQRVDKQEQMPTPKELAV
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
RGERWGPYRTYAAFYLWKIADFSVATKVPTPRSQE
CCCCCCCHHHHHHHHHHHHHCCHHEECCCCCCCCC
>Mature Secondary Structure
MEAAFAHVSRRDRALGAWMKRIGPIAPQPGWHKPFDPVDALARAILFQQLSGKAASTIVA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
RVEVAIGAQRLHADTLGRIDDAALRACGVSGNKALALRDLARRESEGEIPSLRRLAFMDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCH
EAIVQALVPVRGIGRWTVEMMLMFRLGRPDLLPIDDLGVRKGAQRVDKQEQMPTPKELAV
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
RGERWGPYRTYAAFYLWKIADFSVATKVPTPRSQE
CCCCCCCHHHHHHHHHHHHHCCHHEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]