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The map label for this gene is fabD [H]

Identifier: 21241881

GI number: 21241881

Start: 1276383

End: 1277327

Strand: Direct

Name: fabD [H]

Synonym: XAC1126

Alternate gene names: 21241881

Gene position: 1276383-1277327 (Clockwise)

Preceding gene: 21241879

Following gene: 21241882

Centisome position: 24.66

GC content: 69.84

Gene sequence:

>945_bases
GTGACCGAATCCACTCTCGCCTTCGTGTTTCCCGGCCAGGGCTCGCAGTCCTTAGGCATGCTGGCCGAACTGTCCGAACT
GCACCCGCAGATTCGCGAAACGTTCGCCGAAGCCTCCGAGGGCGCTGGCGTCGACTTGTGGGCGTTGTCCCAGGGCGGCC
CGGAAGAAATGCTCAATCGCACCGAATACACCCAGCCCGCCTTGTTGGCTGCGGGCGTTGCGGTGTGGCGTCTGTGGACT
GCCCAGCGCGGGCAGCGCCCGGTGCTGCTGGCGGGACACAGCCTGGGCGAATACACCGCGCTGGTCGCGGCTGGCGCCTT
GTCGCTGCACGACGGTGCGCATCTGGTGCGGTTGCGCGGCCAGTTCATGCAGGCTGCGGCACCGGCGGGCGTCGGCGCGA
TGGCTGCGGTGCTGGGCGCCGAAGACGCCGTGGTGCAGGAGGTCTGTGACCAGGCGTCCGGCAGCGACGTGGTGGTGCCG
GCCAACTTCAATTCGCCCGGTCAGATCGTGATCGGCGGCCACGCTGCGGCGGTGGATCGCGCGCTGGGGCTGCTGGCCGA
GCGCGGCGTGCGCAAGGCGGTCAAGCTGGCAGTGAGCGTGCCCTCGCACACCCCGCTGATGCGCGAAGCCGCCAATCAGC
TCGGCGAGGCGATGGCCGGGCTGACCTGGCACGCCCCGCAGATTCCGGTGGTGCAGAACGTGGACGCGCGCGTGCATGAG
GGCAGCACCGCCATCCGCCAGGCCTTGGTGGAACAGCTCTACCTGCCGGTGCAATGGACCGGCTGCGTGCAGGCGCTCGC
CAGCCAGGGCATCACCCGCATTGCCGAATGCGGCCCGGGCAAGGTGCTGAGCGGGCTGATCAAGCGCATCGACAAGAGCC
TGGATGCGCGGCCGCTGGCAACGCCCGCCGACTATGCCGGCGCGCTCGACGCGTGGGCGCACTGA

Upstream 100 bases:

>100_bases
GTCGCGACACAGTCGCGTGGCCTTCTGCATACGCGGCAGTACAGACGCCGGGGCGATTTCGCACGTATGATCCCGGCTCG
ATTTTTGTAGGCAGCAACGC

Downstream 100 bases:

>100_bases
TCCAACGCCGCTGCCGGTCGTGCCGGCATCCCTCGACGTTCGCGGCCACGGTTGCGGCGTCCCCCATCGAGGAACAGCAA
TCATGAGCAAGCCCCTGCAG

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTESTLAFVFPGQGSQSLGMLAELSELHPQIRETFAEASEGAGVDLWALSQGGPEEMLNRTEYTQPALLAAGVAVWRLWT
AQRGQRPVLLAGHSLGEYTALVAAGALSLHDGAHLVRLRGQFMQAAAPAGVGAMAAVLGAEDAVVQEVCDQASGSDVVVP
ANFNSPGQIVIGGHAAAVDRALGLLAERGVRKAVKLAVSVPSHTPLMREAANQLGEAMAGLTWHAPQIPVVQNVDARVHE
GSTAIRQALVEQLYLPVQWTGCVQALASQGITRIAECGPGKVLSGLIKRIDKSLDARPLATPADYAGALDAWAH

Sequences:

>Translated_314_residues
MTESTLAFVFPGQGSQSLGMLAELSELHPQIRETFAEASEGAGVDLWALSQGGPEEMLNRTEYTQPALLAAGVAVWRLWT
AQRGQRPVLLAGHSLGEYTALVAAGALSLHDGAHLVRLRGQFMQAAAPAGVGAMAAVLGAEDAVVQEVCDQASGSDVVVP
ANFNSPGQIVIGGHAAAVDRALGLLAERGVRKAVKLAVSVPSHTPLMREAANQLGEAMAGLTWHAPQIPVVQNVDARVHE
GSTAIRQALVEQLYLPVQWTGCVQALASQGITRIAECGPGKVLSGLIKRIDKSLDARPLATPADYAGALDAWAH
>Mature_313_residues
TESTLAFVFPGQGSQSLGMLAELSELHPQIRETFAEASEGAGVDLWALSQGGPEEMLNRTEYTQPALLAAGVAVWRLWTA
QRGQRPVLLAGHSLGEYTALVAAGALSLHDGAHLVRLRGQFMQAAAPAGVGAMAAVLGAEDAVVQEVCDQASGSDVVVPA
NFNSPGQIVIGGHAAAVDRALGLLAERGVRKAVKLAVSVPSHTPLMREAANQLGEAMAGLTWHAPQIPVVQNVDARVHEG
STAIRQALVEQLYLPVQWTGCVQALASQGITRIAECGPGKVLSGLIKRIDKSLDARPLATPADYAGALDAWAH

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=32.7759197324415, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=43.1192660550459, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=52.7687296416938, Blast_Score=321, Evalue=4e-89,
Organism=Caenorhabditis elegans, GI71984332, Length=299, Percent_Identity=29.0969899665552, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=29.4915254237288, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24665753, Length=307, Percent_Identity=33.2247557003257, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32758; Mature: 32627

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESTLAFVFPGQGSQSLGMLAELSELHPQIRETFAEASEGAGVDLWALSQGGPEEMLNR
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHH
TEYTQPALLAAGVAVWRLWTAQRGQRPVLLAGHSLGEYTALVAAGALSLHDGAHLVRLRG
HCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHH
QFMQAAAPAGVGAMAAVLGAEDAVVQEVCDQASGSDVVVPANFNSPGQIVIGGHAAAVDR
HHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCHHHHHHH
ALGLLAERGVRKAVKLAVSVPSHTPLMREAANQLGEAMAGLTWHAPQIPVVQNVDARVHE
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHC
GSTAIRQALVEQLYLPVQWTGCVQALASQGITRIAECGPGKVLSGLIKRIDKSLDARPLA
CHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
TPADYAGALDAWAH
CCHHHHHHHHHCCC
>Mature Secondary Structure 
TESTLAFVFPGQGSQSLGMLAELSELHPQIRETFAEASEGAGVDLWALSQGGPEEMLNR
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHH
TEYTQPALLAAGVAVWRLWTAQRGQRPVLLAGHSLGEYTALVAAGALSLHDGAHLVRLRG
HCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHH
QFMQAAAPAGVGAMAAVLGAEDAVVQEVCDQASGSDVVVPANFNSPGQIVIGGHAAAVDR
HHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCHHHHHHH
ALGLLAERGVRKAVKLAVSVPSHTPLMREAANQLGEAMAGLTWHAPQIPVVQNVDARVHE
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHC
GSTAIRQALVEQLYLPVQWTGCVQALASQGITRIAECGPGKVLSGLIKRIDKSLDARPLA
CHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
TPADYAGALDAWAH
CCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]