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The map label for this gene is tig

Identifier: 21241837

GI number: 21241837

Start: 1231479

End: 1232771

Strand: Direct

Name: tig

Synonym: XAC1077

Alternate gene names: 21241837

Gene position: 1231479-1232771 (Clockwise)

Preceding gene: 21241833

Following gene: 21241838

Centisome position: 23.79

GC content: 65.58

Gene sequence:

>1293_bases
ATGCAAGCATCGATCGAATCCACCGGCAATCTGGAACGCCGACTGACCTTCACCCTGCCGCAGGAGCGCCTGGAGACGCA
CGTCGGTGGCCGCCTGCGCGAGCTTGCGCGGACCACGCGCATCAAGGGCTTCCGTCCCGGCAAGGTGCCGACCAAGGTGA
TCGAGCAGCGCTTCGGTCAGCAGGTGCGTGCCGAGGCGATGGAAGGCCTGCTGCGTGAGACCTTCGATTCGGCCGTGCGC
GAGCACTCGTTGCGTCTGGCCGGCAACCCGCGTATCGATCAGGGCGAGACCGATTTCGACTTCGTCGCCACCTTCGAAGT
GGTGCCGGATTTCGGCGACATCGACGTGACCAAGCTGTCGGTGGTGCGCGCGACCGCTGAAGTGACCGATGCCGACATCG
ACCAGATGATCGAAAACCTGCGCCTGCAGCGCCGCACCTGGAATCCGGTCGAGCGCGGTGCGCAGGTCGGCGACCTGGTG
GCGCTGGAGACCTGGTCGCAGGCCGGCGACGAGCGCCTGCCCGCCGAAGGCGTGGAGACCGGCAGCAGCGTGCTGGGTTC
GGGCGTGATGTTCGACCAGATCGAAAAGGGCCTGGAAGGCCTCACCAAGGGTGAAGAAAAGACCCTGACCGTCGATTTCC
CCGCAGAATGGCGCGTGCCGCAGCTGGCGGGCAAGACCGTGCAGGTGCACGTCAAGGCGGTCGAAGTCTCCGAGCCGGTG
TTGCCGGCAGTGGACAAGGACTTCATCAAGAGCTTCGGCGTGAAGAGTGGCGATGCCGAGCAGTTCCGCGCCGATATCCG
CACCAACCTGGAGCGCGAGCTCAAGGGTGCGCTGATGAACCGCCTGCGCCGCGAAGTGGGCGAGCAGCTGATTGCCGCCT
ACGCGCATGTCGAAATGCCGCCGCGTCTGGTCGAGAGCGAAGCGCGTTCGATGCTGGCCCAGCAGGTCGAGCAGGTCCGC
CGCAGCGGTCGCGATCCGGGTCAGGTGCCGGCCGACGCGCACCAGGGATTCATGGATGCCGCCGCCAAGCGCGTGCTGGT
CGGTCTGCTGGTGGGTGAAGTGGCGCGCCGCAACGAATTGCGCCTGGAATCCAAGCGCGTCAGCGAAACGCTGCGTCTGA
TCGCTTCGACCTACGAAGAGCCGGAACAGGTCATTGAGATGTACCGCAACGACCCCCAACTGATGAACGGGCTGCAGAGC
CGCGTGATGGAAGAGCAGGTGATCGACTGGATCGCCGAGCGCGCCCAGCACACCGAGCAGTCGCTGTCGTTCCAGGACGC
CATCCGCGTCTGA

Upstream 100 bases:

>100_bases
TATCGGCGAAACTACAAGGCTCGGCGGCATTCTCGCCATCCGTCAACCCGCATCTTCCATCTCGTGCCGACGCTGTGCGC
TGTCGGTGGCAGGAGTCAAC

Downstream 100 bases:

>100_bases
TCCGGCAGTAAGAGAAGAACCGCGCCCGCAGTCAGGGGTGCGGATGTCGAACACGGGCAGCGGCACAGGCCGCTGCCACA
ACGGGAAGACTGATGAGCAT

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MQASIESTGNLERRLTFTLPQERLETHVGGRLRELARTTRIKGFRPGKVPTKVIEQRFGQQVRAEAMEGLLRETFDSAVR
EHSLRLAGNPRIDQGETDFDFVATFEVVPDFGDIDVTKLSVVRATAEVTDADIDQMIENLRLQRRTWNPVERGAQVGDLV
ALETWSQAGDERLPAEGVETGSSVLGSGVMFDQIEKGLEGLTKGEEKTLTVDFPAEWRVPQLAGKTVQVHVKAVEVSEPV
LPAVDKDFIKSFGVKSGDAEQFRADIRTNLERELKGALMNRLRREVGEQLIAAYAHVEMPPRLVESEARSMLAQQVEQVR
RSGRDPGQVPADAHQGFMDAAAKRVLVGLLVGEVARRNELRLESKRVSETLRLIASTYEEPEQVIEMYRNDPQLMNGLQS
RVMEEQVIDWIAERAQHTEQSLSFQDAIRV

Sequences:

>Translated_430_residues
MQASIESTGNLERRLTFTLPQERLETHVGGRLRELARTTRIKGFRPGKVPTKVIEQRFGQQVRAEAMEGLLRETFDSAVR
EHSLRLAGNPRIDQGETDFDFVATFEVVPDFGDIDVTKLSVVRATAEVTDADIDQMIENLRLQRRTWNPVERGAQVGDLV
ALETWSQAGDERLPAEGVETGSSVLGSGVMFDQIEKGLEGLTKGEEKTLTVDFPAEWRVPQLAGKTVQVHVKAVEVSEPV
LPAVDKDFIKSFGVKSGDAEQFRADIRTNLERELKGALMNRLRREVGEQLIAAYAHVEMPPRLVESEARSMLAQQVEQVR
RSGRDPGQVPADAHQGFMDAAAKRVLVGLLVGEVARRNELRLESKRVSETLRLIASTYEEPEQVIEMYRNDPQLMNGLQS
RVMEEQVIDWIAERAQHTEQSLSFQDAIRV
>Mature_430_residues
MQASIESTGNLERRLTFTLPQERLETHVGGRLRELARTTRIKGFRPGKVPTKVIEQRFGQQVRAEAMEGLLRETFDSAVR
EHSLRLAGNPRIDQGETDFDFVATFEVVPDFGDIDVTKLSVVRATAEVTDADIDQMIENLRLQRRTWNPVERGAQVGDLV
ALETWSQAGDERLPAEGVETGSSVLGSGVMFDQIEKGLEGLTKGEEKTLTVDFPAEWRVPQLAGKTVQVHVKAVEVSEPV
LPAVDKDFIKSFGVKSGDAEQFRADIRTNLERELKGALMNRLRREVGEQLIAAYAHVEMPPRLVESEARSMLAQQVEQVR
RSGRDPGQVPADAHQGFMDAAAKRVLVGLLVGEVARRNELRLESKRVSETLRLIASTYEEPEQVIEMYRNDPQLMNGLQS
RVMEEQVIDWIAERAQHTEQSLSFQDAIRV

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=433, Percent_Identity=36.0277136258661, Blast_Score=251, Evalue=8e-68,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_XANAC (Q8PNI6)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641419.1
- ProteinModelPortal:   Q8PNI6
- SMR:   Q8PNI6
- GeneID:   1155148
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1077
- NMPDR:   fig|190486.1.peg.1063
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- ProtClustDB:   PRK01490
- BioCyc:   XAXO190486:XAC1077-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 48246; Mature: 48246

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQASIESTGNLERRLTFTLPQERLETHVGGRLRELARTTRIKGFRPGKVPTKVIEQRFGQ
CCCCCCCCCCCHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
QVRAEAMEGLLRETFDSAVREHSLRLAGNPRIDQGETDFDFVATFEVVPDFGDIDVTKLS
HHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCCHHHEEEEEECCCCCCCCHHHHH
VVRATAEVTDADIDQMIENLRLQRRTWNPVERGAQVGDLVALETWSQAGDERLPAEGVET
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHCC
GSSVLGSGVMFDQIEKGLEGLTKGEEKTLTVDFPAEWRVPQLAGKTVQVHVKAVEVSEPV
CHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHCCCEEEEEEEEEECCCCC
LPAVDKDFIKSFGVKSGDAEQFRADIRTNLERELKGALMNRLRREVGEQLIAAYAHVEMP
CCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PRLVESEARSMLAQQVEQVRRSGRDPGQVPADAHQGFMDAAAKRVLVGLLVGEVARRNEL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLESKRVSETLRLIASTYEEPEQVIEMYRNDPQLMNGLQSRVMEEQVIDWIAERAQHTEQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSFQDAIRV
HCCHHHHHCC
>Mature Secondary Structure
MQASIESTGNLERRLTFTLPQERLETHVGGRLRELARTTRIKGFRPGKVPTKVIEQRFGQ
CCCCCCCCCCCHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
QVRAEAMEGLLRETFDSAVREHSLRLAGNPRIDQGETDFDFVATFEVVPDFGDIDVTKLS
HHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCCHHHEEEEEECCCCCCCCHHHHH
VVRATAEVTDADIDQMIENLRLQRRTWNPVERGAQVGDLVALETWSQAGDERLPAEGVET
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHCC
GSSVLGSGVMFDQIEKGLEGLTKGEEKTLTVDFPAEWRVPQLAGKTVQVHVKAVEVSEPV
CHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHCCCEEEEEEEEEECCCCC
LPAVDKDFIKSFGVKSGDAEQFRADIRTNLERELKGALMNRLRREVGEQLIAAYAHVEMP
CCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PRLVESEARSMLAQQVEQVRRSGRDPGQVPADAHQGFMDAAAKRVLVGLLVGEVARRNEL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLESKRVSETLRLIASTYEEPEQVIEMYRNDPQLMNGLQSRVMEEQVIDWIAERAQHTEQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSFQDAIRV
HCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217