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The map label for this gene is moaB [H]

Identifier: 21241712

GI number: 21241712

Start: 1103606

End: 1104124

Strand: Reverse

Name: moaB [H]

Synonym: XAC0942

Alternate gene names: 21241712

Gene position: 1104124-1103606 (Counterclockwise)

Preceding gene: 21241713

Following gene: 21241711

Centisome position: 21.33

GC content: 64.35

Gene sequence:

>519_bases
ATGCCTTCCAATCTCGATTTCATTCCCTTGCGCCTGTGCGTGCTGACCGTGTCCGACAGCCGCACCCTGGCCGACGACCG
CTCCGGCGATTACCTGGCCGATGTCCTCACCCATGAAGGCCACGTCCTGCACGAACGTGCGCTGTGCCCGGACGACCGTT
ACCGGATGCGGGCGATCGTCTCCGGCTGGATCGCAGATGCGCAGGTGGATGGGATCCTGATCACCGGTGGCACCGGCTTT
ACGGGTCGCGACAGCACCCCGGAAGCGATCACCCCGTTGCTGGACAAGGTCATGCCTGGCTTCGGCGAGATGTTCCGCGC
GATCAGCGTGGAAGAAATCGGCACCTCCTCGCTGCAGTCGCGCGCCTTTGCCGGGCTGGCCAATCACAGCTTCGTGTTCT
GTCTGCCCGGCTCCACCTCGGCCTGCCGCACGGCCTGGGAAAAGATCGTGCGCGCGCAGCTGGATGCGCGCACCAAACCC
TGCAATCTGGCGACATTGCGTCCACGCTTAGGCGAATAG

Upstream 100 bases:

>100_bases
CTAACGGCAGTGCATCAGTCCGTGCCCGATAGTCAGGTGCTCCGTGCAACTTCACACCGCGGCGCTGTACCCGGCCGTCC
AGGCTCGCTAGGCTGCGCGC

Downstream 100 bases:

>100_bases
TCTGCGCGCTTTCCACCGCTGCTGGAACGCGCATGTCGCACTTGAAACGCAAGGCTTATAAAAAGTTGCTGGCGCCAATG
CAGTTGGAACTGGTGGACAT

Product: molybdopterin biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MPSNLDFIPLRLCVLTVSDSRTLADDRSGDYLADVLTHEGHVLHERALCPDDRYRMRAIVSGWIADAQVDGILITGGTGF
TGRDSTPEAITPLLDKVMPGFGEMFRAISVEEIGTSSLQSRAFAGLANHSFVFCLPGSTSACRTAWEKIVRAQLDARTKP
CNLATLRPRLGE

Sequences:

>Translated_172_residues
MPSNLDFIPLRLCVLTVSDSRTLADDRSGDYLADVLTHEGHVLHERALCPDDRYRMRAIVSGWIADAQVDGILITGGTGF
TGRDSTPEAITPLLDKVMPGFGEMFRAISVEEIGTSSLQSRAFAGLANHSFVFCLPGSTSACRTAWEKIVRAQLDARTKP
CNLATLRPRLGE
>Mature_171_residues
PSNLDFIPLRLCVLTVSDSRTLADDRSGDYLADVLTHEGHVLHERALCPDDRYRMRAIVSGWIADAQVDGILITGGTGFT
GRDSTPEAITPLLDKVMPGFGEMFRAISVEEIGTSSLQSRAFAGLANHSFVFCLPGSTSACRTAWEKIVRAQLDARTKPC
NLATLRPRLGE

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=150, Percent_Identity=32, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI10880983, Length=150, Percent_Identity=32, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787000, Length=158, Percent_Identity=55.6962025316456, Blast_Score=189, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18736; Mature: 18604

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSNLDFIPLRLCVLTVSDSRTLADDRSGDYLADVLTHEGHVLHERALCPDDRYRMRAIV
CCCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCEEHHCCCCCCHHHHHHHHH
SGWIADAQVDGILITGGTGFTGRDSTPEAITPLLDKVMPGFGEMFRAISVEEIGTSSLQS
HHHHCCCEECEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHH
RAFAGLANHSFVFCLPGSTSACRTAWEKIVRAQLDARTKPCNLATLRPRLGE
HHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
PSNLDFIPLRLCVLTVSDSRTLADDRSGDYLADVLTHEGHVLHERALCPDDRYRMRAIV
CCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCEEHHCCCCCCHHHHHHHHH
SGWIADAQVDGILITGGTGFTGRDSTPEAITPLLDKVMPGFGEMFRAISVEEIGTSSLQS
HHHHCCCEECEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHH
RAFAGLANHSFVFCLPGSTSACRTAWEKIVRAQLDARTKPCNLATLRPRLGE
HHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]