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The map label for this gene is exo [H]

Identifier: 21241682

GI number: 21241682

Start: 1073055

End: 1074041

Strand: Reverse

Name: exo [H]

Synonym: XAC0912

Alternate gene names: 21241682

Gene position: 1074041-1073055 (Counterclockwise)

Preceding gene: 21241683

Following gene: 21241681

Centisome position: 20.75

GC content: 67.78

Gene sequence:

>987_bases
GTGACCACGCCGACCAACCCGCTCGACGCTGCGCCACTGGCAATCCAGCGCCCGACCCCGCTGTATCTGGTGGATGCCAG
CCTGTACGTGTTCCGTGCCTGGCACTCCATCCCGGACGAATTTCAGGATGCGCAGGGCTGGCCGACCAATGCGGTGCACG
GCTTTGCGCGGTTTCTGCTGGACCTGCTCGAACGCGAGGATCCGCAGTACATCACCATTGCCTTTGACGAAGCCCTGGAC
AGCTGCTTCCGGCATGCGATCTACCCGGCCTACAAAGGCAACCGCACGCCTGCGCCGGATGCGCTGCGCCGCCAGTTCGC
GCATTGCAAGGCGCTGTGCGCAGCGCTCGGGCTGAGCGTGCTGGCCCACCGCGATTACGAGGCCGACGACCTGATCGGTA
GCGCGCTGCACAGCGTGCGGGCGCACGGCTTGCGCGGGGTGATCGTGTCGGCCGACAAGGACCTGTCGCAGTTATTGCTC
GAGCATGACGAGCAGTGGGACTACGCGCGCAACCAGCGCTGGGGCATGGACGGGGTCAAGGCGCGCCATGGCGTGCATGC
GCACCAGATCGCCGACTATCTGGCGTTATGCGGCGATGCCATCGACAACATTCCCGGCGTGACCGGCATCGGCGCCAAAT
CGGCAGCAGTGCTGCTGGCGCACTTCGGCAGCCTGGATGCGCTGCTGGAGCGCATCGACGAAATCCCCTTCCTGCGCCTG
CGCGGCGCGGCGCAAATGGCGGTGCGGCTGCGCGAACAGCGCGAACACGCATTGCTGTGGCGGCAGCTCACCACCATCGC
GCTCGACGCGCCGCTGGCGCTCACCCAGACCGGCTTCACGCGTGCGCACGCCGATGCGGACATGCTGACCGGGTTGTGCG
AGAGCCTGCGCTTCGGCCCGCTCACCCGGCGCCGTCTGCTGGCCGCCAGCACCGGCGTCCCCGCACCGTTTCCTCCCGCT
TCCCTGGCACAAGGTCCCCGCCCATGA

Upstream 100 bases:

>100_bases
ACGAACGCATCGCCGGCTTCATCCACATCGGCACGCCGCGCATGCAGGTGCCCGAACGCGAGCGCCCGGACCCGCGTGCG
CTGCTGCGCGACTGGACCCC

Downstream 100 bases:

>100_bases
ACCGACACGACACCCCGCCCACCGTGGTCTACGAAGGCAAGTACCAGCGCATGGTCGTGCGTGGCACCTGGGAATACTCC
GAACGTGTGCATGCCGGCGG

Product: exodeoxyribonuclease IX

Products: NA

Alternate protein names: Pol I [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTTPTNPLDAAPLAIQRPTPLYLVDASLYVFRAWHSIPDEFQDAQGWPTNAVHGFARFLLDLLEREDPQYITIAFDEALD
SCFRHAIYPAYKGNRTPAPDALRRQFAHCKALCAALGLSVLAHRDYEADDLIGSALHSVRAHGLRGVIVSADKDLSQLLL
EHDEQWDYARNQRWGMDGVKARHGVHAHQIADYLALCGDAIDNIPGVTGIGAKSAAVLLAHFGSLDALLERIDEIPFLRL
RGAAQMAVRLREQREHALLWRQLTTIALDAPLALTQTGFTRAHADADMLTGLCESLRFGPLTRRRLLAASTGVPAPFPPA
SLAQGPRP

Sequences:

>Translated_328_residues
MTTPTNPLDAAPLAIQRPTPLYLVDASLYVFRAWHSIPDEFQDAQGWPTNAVHGFARFLLDLLEREDPQYITIAFDEALD
SCFRHAIYPAYKGNRTPAPDALRRQFAHCKALCAALGLSVLAHRDYEADDLIGSALHSVRAHGLRGVIVSADKDLSQLLL
EHDEQWDYARNQRWGMDGVKARHGVHAHQIADYLALCGDAIDNIPGVTGIGAKSAAVLLAHFGSLDALLERIDEIPFLRL
RGAAQMAVRLREQREHALLWRQLTTIALDAPLALTQTGFTRAHADADMLTGLCESLRFGPLTRRRLLAASTGVPAPFPPA
SLAQGPRP
>Mature_327_residues
TTPTNPLDAAPLAIQRPTPLYLVDASLYVFRAWHSIPDEFQDAQGWPTNAVHGFARFLLDLLEREDPQYITIAFDEALDS
CFRHAIYPAYKGNRTPAPDALRRQFAHCKALCAALGLSVLAHRDYEADDLIGSALHSVRAHGLRGVIVSADKDLSQLLLE
HDEQWDYARNQRWGMDGVKARHGVHAHQIADYLALCGDAIDNIPGVTGIGAKSAAVLLAHFGSLDALLERIDEIPFLRLR
GAAQMAVRLREQREHALLWRQLTTIALDAPLALTQTGFTRAHADADMLTGLCESLRFGPLTRRRLLAASTGVPAPFPPAS
LAQGPRP

Specific function: In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity [H]

COG id: COG0258

COG function: function code L; 5'-3' exonuclease (including N-terminal domain of PolI)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain [H]

Homologues:

Organism=Escherichia coli, GI1790294, Length=285, Percent_Identity=37.1929824561403, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI226510970, Length=250, Percent_Identity=30.4, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR002421
- InterPro:   IPR020047
- InterPro:   IPR019760
- InterPro:   IPR001098
- InterPro:   IPR018320
- InterPro:   IPR002298
- InterPro:   IPR008918
- InterPro:   IPR003583
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; PF00476 DNA_pol_A [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 36066; Mature: 35934

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPTNPLDAAPLAIQRPTPLYLVDASLYVFRAWHSIPDEFQDAQGWPTNAVHGFARFLL
CCCCCCCCCCCCEEECCCCCEEEECHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHH
DLLEREDPQYITIAFDEALDSCFRHAIYPAYKGNRTPAPDALRRQFAHCKALCAALGLSV
HHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAHRDYEADDLIGSALHSVRAHGLRGVIVSADKDLSQLLLEHDEQWDYARNQRWGMDGVK
HHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCHHHCCCCCCCCHH
ARHGVHAHQIADYLALCGDAIDNIPGVTGIGAKSAAVLLAHFGSLDALLERIDEIPFLRL
HHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEHH
RGAAQMAVRLREQREHALLWRQLTTIALDAPLALTQTGFTRAHADADMLTGLCESLRFGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHCCHHHHHHHHHHHHCCC
LTRRRLLAASTGVPAPFPPASLAQGPRP
HHHHHHHHHCCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
TTPTNPLDAAPLAIQRPTPLYLVDASLYVFRAWHSIPDEFQDAQGWPTNAVHGFARFLL
CCCCCCCCCCCEEECCCCCEEEECHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHH
DLLEREDPQYITIAFDEALDSCFRHAIYPAYKGNRTPAPDALRRQFAHCKALCAALGLSV
HHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAHRDYEADDLIGSALHSVRAHGLRGVIVSADKDLSQLLLEHDEQWDYARNQRWGMDGVK
HHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCHHHCCCCCCCCHH
ARHGVHAHQIADYLALCGDAIDNIPGVTGIGAKSAAVLLAHFGSLDALLERIDEIPFLRL
HHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEHH
RGAAQMAVRLREQREHALLWRQLTTIALDAPLALTQTGFTRAHADADMLTGLCESLRFGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHCCHHHHHHHHHHHHCCC
LTRRRLLAASTGVPAPFPPASLAQGPRP
HHHHHHHHHCCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA