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The map label for this gene is vanR [H]

Identifier: 21241647

GI number: 21241647

Start: 1038804

End: 1039478

Strand: Reverse

Name: vanR [H]

Synonym: XAC0877

Alternate gene names: 21241647

Gene position: 1039478-1038804 (Counterclockwise)

Preceding gene: 21241651

Following gene: 21241641

Centisome position: 20.08

GC content: 65.48

Gene sequence:

>675_bases
ATGGAGCCAATGGCGAACAACCACCGATTGCAAGCGATTCAGCAGCTACGCGAATTGATCCTGTGCGGCACCTTCGCGCC
CGGCGAGCGCGTCACCGAGGCGGCACTGGCCGAGCGCCTGGCGATTTCGCGCACGCCGATCCGTCAGGCCCTGCCGGCGT
TATGCCAGGAAGGCCTGCTGGTGCAGGCGGGCAGCCGTGGTTACGCCGTGCGGCGCTTCAGCCAGCAGGAAAGCCTGGAT
GCCCTGGCGGTGCGCGCAATGATGGAAGGCATGGCCGCACGCACCGTCGCCGAACAGGGCGCCCCGGCCGAGCTGCTCGC
CACGTTGCATGCCTGTCTGGGCGAAGGCGACCGCATCCTGGCCAGCCGCAACCTCTGCGCCGACGATGAGCAGGCGTATG
GCGCAATGAACGCCCGTTTCCACCGCGCCATCGTGGAGGCGGCCAACAAGCCGATCCTGACCGAAACCGTGGAACGCTGC
ACATTGGTGCCGTTCGTCAGCCCGGTCAACGTCGTGTTCGGCCAACGCACTGCCGCGCTTGCCTACGACGATCTGTTTTA
CGGACACAGGCAACACGGCGCGATCGTTTCGGCCATCGAACAACGCGATGGCGCACGCGCGGAATTACTGTTCCGCGAAC
ACGCCAACACGCAACGGCACAGCATGGGAATCTGA

Upstream 100 bases:

>100_bases
TCCAAATTGCCATCAAGCGATCTCATCCGCAAGGTCTTTATACCTGTAAGTGAGAGTTTTCCCTGTCGAAGGAACGTGCG
CTGCGGTATGGCGCGAGAGA

Downstream 100 bases:

>100_bases
AACGCACGTGTTGCGGCGGTTGACCCATTGCACGCGCTGTGCCGCATATTGATGGATGACGTGGAGTGCACAGCGCAAAC
AGCGCAAGCCGATCCACTCG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MEPMANNHRLQAIQQLRELILCGTFAPGERVTEAALAERLAISRTPIRQALPALCQEGLLVQAGSRGYAVRRFSQQESLD
ALAVRAMMEGMAARTVAEQGAPAELLATLHACLGEGDRILASRNLCADDEQAYGAMNARFHRAIVEAANKPILTETVERC
TLVPFVSPVNVVFGQRTAALAYDDLFYGHRQHGAIVSAIEQRDGARAELLFREHANTQRHSMGI

Sequences:

>Translated_224_residues
MEPMANNHRLQAIQQLRELILCGTFAPGERVTEAALAERLAISRTPIRQALPALCQEGLLVQAGSRGYAVRRFSQQESLD
ALAVRAMMEGMAARTVAEQGAPAELLATLHACLGEGDRILASRNLCADDEQAYGAMNARFHRAIVEAANKPILTETVERC
TLVPFVSPVNVVFGQRTAALAYDDLFYGHRQHGAIVSAIEQRDGARAELLFREHANTQRHSMGI
>Mature_224_residues
MEPMANNHRLQAIQQLRELILCGTFAPGERVTEAALAERLAISRTPIRQALPALCQEGLLVQAGSRGYAVRRFSQQESLD
ALAVRAMMEGMAARTVAEQGAPAELLATLHACLGEGDRILASRNLCADDEQAYGAMNARFHRAIVEAANKPILTETVERC
TLVPFVSPVNVVFGQRTAALAYDDLFYGHRQHGAIVSAIEQRDGARAELLFREHANTQRHSMGI

Specific function: Unknown

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082149, Length=214, Percent_Identity=30.3738317757009, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000485
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 24488; Mature: 24488

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPMANNHRLQAIQQLRELILCGTFAPGERVTEAALAERLAISRTPIRQALPALCQEGLL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEE
VQAGSRGYAVRRFSQQESLDALAVRAMMEGMAARTVAEQGAPAELLATLHACLGEGDRIL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEE
ASRNLCADDEQAYGAMNARFHRAIVEAANKPILTETVERCTLVPFVSPVNVVFGQRTAAL
ECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHH
AYDDLFYGHRQHGAIVSAIEQRDGARAELLFREHANTQRHSMGI
HHHHHHHCCHHCCHHHHHHHHCCCCHHHHHHHHHCCCHHHCCCC
>Mature Secondary Structure
MEPMANNHRLQAIQQLRELILCGTFAPGERVTEAALAERLAISRTPIRQALPALCQEGLL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEE
VQAGSRGYAVRRFSQQESLDALAVRAMMEGMAARTVAEQGAPAELLATLHACLGEGDRIL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEE
ASRNLCADDEQAYGAMNARFHRAIVEAANKPILTETVERCTLVPFVSPVNVVFGQRTAAL
ECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHH
AYDDLFYGHRQHGAIVSAIEQRDGARAELLFREHANTQRHSMGI
HHHHHHHCCHHCCHHHHHHHHCCCCHHHHHHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]