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The map label for this gene is 21241639

Identifier: 21241639

GI number: 21241639

Start: 1031256

End: 1032167

Strand: Reverse

Name: 21241639

Synonym: XAC0869

Alternate gene names: NA

Gene position: 1032167-1031256 (Counterclockwise)

Preceding gene: 21241640

Following gene: 21241638

Centisome position: 19.94

GC content: 67.21

Gene sequence:

>912_bases
ATGTTGGTCTTTACCCATCCCGCCTGCCTCGGTCACGACGCCGGCCCTGAGCACCCGGAAAGCCCCGCCCGCCTGGAAGC
GGTGGTCCAGGCCCTGCGCGGCGCATTCCCGGATCTGGACTGGCGCGAAGCGCCGTTGGCCAAGCTGGGCGACCTGTGCC
GCGTGCACGAGCGCGAGCAGGTGGATGCGGTACTGGAAACCGCCTTCGACGGCTATCGTCAGCTGGACGTGGATACGCGC
ATGGTGCCGGCCTCGCGCGCGGCCGCCTTGCGCGCCGCCGGCGCCGGTATCGCCGCCGTCGATGCGGTGATGCAGGACCA
GACCCGCACCGCCTTCTGCGCCGTGCGTCCGCCCGGTCACCACGCCACCGCACAGGTGTCGATGGGATTTTGCCTGTTCA
ACAACATCGCCGTGGCCGCCGCCCATGCGCGCGACCGGCATGGGCTGGAGCGCATCACCATCGTGGATTTCGACGTCCAT
CACGGTAACGGCACCCAGGCGATCTTCGAACGCGACCCCGCCGTGCAGTACCTGAGCACCCACCAGTCCGGGCTGTATCC
GCATTCGGGCAGCGTCTACGAGCGCGGCGTCGGCAATATCCACAACCTGCTGCTGCCACCGGGCAGCGATGGACTGCGCT
TCCGCAATGTCTGGGAAGACGAGATGCTGCCGCTCGTCGATGCCTTCCGCCCGCAGTTGATCCTGATCTCCGCCGGCTTC
GATGCGCATCTGCGCGACCCACTGGCCGACCTGATGCTGGACGACGACGATTTCGCCTGGCTCACCGGCGCGCTGCGCAC
CCTGGCCGACCGCCATGCACGCGGCCGCGTGGTCTCGATGCTGGAGGGCGGCTACGACCTGCAGGCGCTTGCAGAATGCT
CAATTGCTCATGTTAGAGTTCTCTTGCAGTAA

Upstream 100 bases:

>100_bases
TGCTGGCGCGTGCCGATGGTCGGCAGGAAGTCCTGTGGCGGCACGACCGCCGACGCGGTTGAGCATGCGCCCGGGTCGGC
GCAGAGGCTAGAGTTGCCCC

Downstream 100 bases:

>100_bases
ACCACTCTCAATTTACTTTTAAAGGATAAAAAGTGAGAAAGTTGAATATTGTATTGGGTCTAGCAGCTACGATTGCATGT
GGGCAAGTCAATGCCCAAAT

Product: acetoin utilization family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MLVFTHPACLGHDAGPEHPESPARLEAVVQALRGAFPDLDWREAPLAKLGDLCRVHEREQVDAVLETAFDGYRQLDVDTR
MVPASRAAALRAAGAGIAAVDAVMQDQTRTAFCAVRPPGHHATAQVSMGFCLFNNIAVAAAHARDRHGLERITIVDFDVH
HGNGTQAIFERDPAVQYLSTHQSGLYPHSGSVYERGVGNIHNLLLPPGSDGLRFRNVWEDEMLPLVDAFRPQLILISAGF
DAHLRDPLADLMLDDDDFAWLTGALRTLADRHARGRVVSMLEGGYDLQALAECSIAHVRVLLQ

Sequences:

>Translated_303_residues
MLVFTHPACLGHDAGPEHPESPARLEAVVQALRGAFPDLDWREAPLAKLGDLCRVHEREQVDAVLETAFDGYRQLDVDTR
MVPASRAAALRAAGAGIAAVDAVMQDQTRTAFCAVRPPGHHATAQVSMGFCLFNNIAVAAAHARDRHGLERITIVDFDVH
HGNGTQAIFERDPAVQYLSTHQSGLYPHSGSVYERGVGNIHNLLLPPGSDGLRFRNVWEDEMLPLVDAFRPQLILISAGF
DAHLRDPLADLMLDDDDFAWLTGALRTLADRHARGRVVSMLEGGYDLQALAECSIAHVRVLLQ
>Mature_303_residues
MLVFTHPACLGHDAGPEHPESPARLEAVVQALRGAFPDLDWREAPLAKLGDLCRVHEREQVDAVLETAFDGYRQLDVDTR
MVPASRAAALRAAGAGIAAVDAVMQDQTRTAFCAVRPPGHHATAQVSMGFCLFNNIAVAAAHARDRHGLERITIVDFDVH
HGNGTQAIFERDPAVQYLSTHQSGLYPHSGSVYERGVGNIHNLLLPPGSDGLRFRNVWEDEMLPLVDAFRPQLILISAGF
DAHLRDPLADLMLDDDDFAWLTGALRTLADRHARGRVVSMLEGGYDLQALAECSIAHVRVLLQ

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=307, Percent_Identity=38.4364820846906, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI13128864, Length=312, Percent_Identity=35.8974358974359, Blast_Score=164, Evalue=6e-41,
Organism=Homo sapiens, GI17158039, Length=232, Percent_Identity=39.6551724137931, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI30795202, Length=232, Percent_Identity=39.6551724137931, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI30795204, Length=232, Percent_Identity=39.6551724137931, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI153085395, Length=233, Percent_Identity=39.4849785407725, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI226529806, Length=300, Percent_Identity=36.6666666666667, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI148539870, Length=232, Percent_Identity=37.9310344827586, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI169234807, Length=232, Percent_Identity=37.9310344827586, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI62750349, Length=244, Percent_Identity=36.0655737704918, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI62750347, Length=244, Percent_Identity=36.0655737704918, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI13128862, Length=259, Percent_Identity=25.4826254826255, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI8923769, Length=228, Percent_Identity=25, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=306, Percent_Identity=33.9869281045752, Blast_Score=160, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17540332, Length=306, Percent_Identity=33.9869281045752, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI193206283, Length=306, Percent_Identity=33.9869281045752, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI193209491, Length=331, Percent_Identity=33.5347432024169, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI25154020, Length=226, Percent_Identity=32.3008849557522, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI25154022, Length=226, Percent_Identity=31.858407079646, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17537347, Length=306, Percent_Identity=33.6601307189542, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17534739, Length=189, Percent_Identity=28.042328042328, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324307, Length=319, Percent_Identity=31.0344827586207, Blast_Score=139, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6325141, Length=318, Percent_Identity=26.1006289308176, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6325325, Length=170, Percent_Identity=28.2352941176471, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323999, Length=270, Percent_Identity=21.8518518518519, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281360899, Length=312, Percent_Identity=33.974358974359, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24642142, Length=312, Percent_Identity=33.974358974359, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24642144, Length=312, Percent_Identity=33.974358974359, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24642146, Length=312, Percent_Identity=33.974358974359, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24641720, Length=338, Percent_Identity=34.0236686390533, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281360799, Length=338, Percent_Identity=34.0236686390533, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281360801, Length=338, Percent_Identity=34.0236686390533, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24644244, Length=313, Percent_Identity=24.2811501597444, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33122; Mature: 33122

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVFTHPACLGHDAGPEHPESPARLEAVVQALRGAFPDLDWREAPLAKLGDLCRVHEREQ
CEEEECCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
VDAVLETAFDGYRQLDVDTRMVPASRAAALRAAGAGIAAVDAVMQDQTRTAFCAVRPPGH
HHHHHHHHHCCCEEECCCCEECCHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCC
HATAQVSMGFCLFNNIAVAAAHARDRHGLERITIVDFDVHHGNGTQAIFERDPAVQYLST
CCEEEEEECHHHHHCHHHEEHHHHHCCCCCEEEEEEEEEECCCCCCEECCCCCHHHHHHH
HQSGLYPHSGSVYERGVGNIHNLLLPPGSDGLRFRNVWEDEMLPLVDAFRPQLILISAGF
HCCCCCCCCCCHHHHCCCCHHHEECCCCCCCCEECCCCHHHHHHHHHHCCCEEEEEECCC
DAHLRDPLADLMLDDDDFAWLTGALRTLADRHARGRVVSMLEGGYDLQALAECSIAHVRV
CCHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEHHHCCCCCHHHHHHHHHHHHHE
LLQ
ECC
>Mature Secondary Structure
MLVFTHPACLGHDAGPEHPESPARLEAVVQALRGAFPDLDWREAPLAKLGDLCRVHEREQ
CEEEECCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
VDAVLETAFDGYRQLDVDTRMVPASRAAALRAAGAGIAAVDAVMQDQTRTAFCAVRPPGH
HHHHHHHHHCCCEEECCCCEECCHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCC
HATAQVSMGFCLFNNIAVAAAHARDRHGLERITIVDFDVHHGNGTQAIFERDPAVQYLST
CCEEEEEECHHHHHCHHHEEHHHHHCCCCCEEEEEEEEEECCCCCCEECCCCCHHHHHHH
HQSGLYPHSGSVYERGVGNIHNLLLPPGSDGLRFRNVWEDEMLPLVDAFRPQLILISAGF
HCCCCCCCCCCHHHHCCCCHHHEECCCCCCCCEECCCCHHHHHHHHHHCCCEEEEEECCC
DAHLRDPLADLMLDDDDFAWLTGALRTLADRHARGRVVSMLEGGYDLQALAECSIAHVRV
CCHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEHHHCCCCCHHHHHHHHHHHHHE
LLQ
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]