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The map label for this gene is ribD [H]

Identifier: 21241517

GI number: 21241517

Start: 886051

End: 887160

Strand: Direct

Name: ribD [H]

Synonym: XAC0746

Alternate gene names: 21241517

Gene position: 886051-887160 (Clockwise)

Preceding gene: 21241516

Following gene: 21241519

Centisome position: 17.12

GC content: 68.38

Gene sequence:

>1110_bases
ATGAGTGAGGCCGCAACGACCGCCAGTGCCGACGACCATCGCTGGATGGCGCAGGCGTTGCGTCTGGCCGAGCGCGGCGC
CTACACCACCCGCCCCAATCCGATGGTGGGCTGCGTGATCGTGCGCGATGGCGTATGCGTGGGCGAGGGCTTTCATCAAC
GTGCCGGCGGCCCGCATGCCGAAGTCTTCGCGCTGCGTGCAGCGGGTGAGTTGGCGCGCGGTGCCACCGCGTATGTGACG
CTGGAGCCATGCGCGCATTACGGACGCACGCCGCCGTGTGCGCTGGCCTTGATCGAGGCAGGCGTCAGACGTGTGGTCGC
GGCGATGGCCGACCCGTTTCCGCAGGTCAATGGCGGCGGTTTCGCGTTGCTGCGCGAGGCAGGGATCGAAGTGCTGAGCG
GCGTGATGCAGGCGCAGGCGCGCACGCTTAACCGGGGATTTCTGTCGCGGGTGGAGCGTGGGCGGCCGTGGTTGCGGGTC
AAACTCGGCGCCAGCCTGGACGGCCGTACCGCGCTGGCCAGCGGCGAATCCAAATGGATCACCAGTGCCGATGCGCGTGC
AGATGTGCAGCGCTGGCGCGCACGTGCGGGCGCGATCCTGACCGGTGCAGGTACGGTGATGGCCGACGACCCATCCATGA
CGGTGCGGCTGGGCGAGGACACGCCGGTCGTGCCGCCGTTGCGCGTGGTGCTCGATGCCAGGCTGCGGACGTTGGCGTGC
AGGAACATTCGTCAGGGCGATGCGCCCACGCTGTATCTGCATGGCGAGAATGTGGCCGCGCAGTCGCTGGACGATGCGCA
GTTCCTTGCGATGCCGTTGCATGCCGGCCGCTTCGATCTGGCGGCTGTGTTGGCCCTGCTAGCCGAGCGCGGCATCAACG
AAGTCCACGTGGAAGGCGGCGCCACGCTGAGCGGTGCGCTGCTGCAGGCCGGGCTGGTCGACGAACTGCTGGTCTACATG
GCCCCGGTGTTGCTGGGCGACACCGCAAAGCCCTTGCTCGCTGGCCTTGGCATCGAAACGATGGCGCAGCGCGCTGCGCT
GCAGCTGCTGGATGTGCGCCAGCTGGGCCAGGATCTGCGTCTGCGCTATGCGCCGGTTGTTGCCGGGTGA

Upstream 100 bases:

>100_bases
TGCCGTTCTACCAGCGCCTGGGATGGCAGACACATACCGAATTATTGCTGGGCCCGATGCAGATCGTGGTGATGCGCATT
GCGCCGGGAGTGGTGACGCA

Downstream 100 bases:

>100_bases
GCGCTGCATGGGGCGCGCGATGCTGCGCGGCCGTGCCGTTACGCGCATAAAAAAGGCCCCGCATGCGGGGCCTTTTTTTC
ATGCGCGACGCCGATCAGAA

Product: 5-amino-6-uracil reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSEAATTASADDHRWMAQALRLAERGAYTTRPNPMVGCVIVRDGVCVGEGFHQRAGGPHAEVFALRAAGELARGATAYVT
LEPCAHYGRTPPCALALIEAGVRRVVAAMADPFPQVNGGGFALLREAGIEVLSGVMQAQARTLNRGFLSRVERGRPWLRV
KLGASLDGRTALASGESKWITSADARADVQRWRARAGAILTGAGTVMADDPSMTVRLGEDTPVVPPLRVVLDARLRTLAC
RNIRQGDAPTLYLHGENVAAQSLDDAQFLAMPLHAGRFDLAAVLALLAERGINEVHVEGGATLSGALLQAGLVDELLVYM
APVLLGDTAKPLLAGLGIETMAQRAALQLLDVRQLGQDLRLRYAPVVAG

Sequences:

>Translated_369_residues
MSEAATTASADDHRWMAQALRLAERGAYTTRPNPMVGCVIVRDGVCVGEGFHQRAGGPHAEVFALRAAGELARGATAYVT
LEPCAHYGRTPPCALALIEAGVRRVVAAMADPFPQVNGGGFALLREAGIEVLSGVMQAQARTLNRGFLSRVERGRPWLRV
KLGASLDGRTALASGESKWITSADARADVQRWRARAGAILTGAGTVMADDPSMTVRLGEDTPVVPPLRVVLDARLRTLAC
RNIRQGDAPTLYLHGENVAAQSLDDAQFLAMPLHAGRFDLAAVLALLAERGINEVHVEGGATLSGALLQAGLVDELLVYM
APVLLGDTAKPLLAGLGIETMAQRAALQLLDVRQLGQDLRLRYAPVVAG
>Mature_368_residues
SEAATTASADDHRWMAQALRLAERGAYTTRPNPMVGCVIVRDGVCVGEGFHQRAGGPHAEVFALRAAGELARGATAYVTL
EPCAHYGRTPPCALALIEAGVRRVVAAMADPFPQVNGGGFALLREAGIEVLSGVMQAQARTLNRGFLSRVERGRPWLRVK
LGASLDGRTALASGESKWITSADARADVQRWRARAGAILTGAGTVMADDPSMTVRLGEDTPVVPPLRVVLDARLRTLACR
NIRQGDAPTLYLHGENVAAQSLDDAQFLAMPLHAGRFDLAAVLALLAERGINEVHVEGGATLSGALLQAGLVDELLVYMA
PVLLGDTAKPLLAGLGIETMAQRAALQLLDVRQLGQDLRLRYAPVVAG

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=361, Percent_Identity=52.0775623268698, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39041; Mature: 38909

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAATTASADDHRWMAQALRLAERGAYTTRPNPMVGCVIVRDGVCVGEGFHQRAGGPHA
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEECCCHHHHCCCCCH
EVFALRAAGELARGATAYVTLEPCAHYGRTPPCALALIEAGVRRVVAAMADPFPQVNGGG
HEEEEHHHHHHHCCCEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FALLREAGIEVLSGVMQAQARTLNRGFLSRVERGRPWLRVKLGASLDGRTALASGESKWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCEE
TSADARADVQRWRARAGAILTGAGTVMADDPSMTVRLGEDTPVVPPLRVVLDARLRTLAC
ECCHHHHHHHHHHHHCCEEEECCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
RNIRQGDAPTLYLHGENVAAQSLDDAQFLAMPLHAGRFDLAAVLALLAERGINEVHVEGG
HCCCCCCCCEEEEECCCHHHCCCCCCHHEEECCCCCCHHHHHHHHHHHHCCCCEEEECCC
ATLSGALLQAGLVDELLVYMAPVLLGDTAKPLLAGLGIETMAQRAALQLLDVRQLGQDLR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LRYAPVVAG
EEECCCCCC
>Mature Secondary Structure 
SEAATTASADDHRWMAQALRLAERGAYTTRPNPMVGCVIVRDGVCVGEGFHQRAGGPHA
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEECCCHHHHCCCCCH
EVFALRAAGELARGATAYVTLEPCAHYGRTPPCALALIEAGVRRVVAAMADPFPQVNGGG
HEEEEHHHHHHHCCCEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FALLREAGIEVLSGVMQAQARTLNRGFLSRVERGRPWLRVKLGASLDGRTALASGESKWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCEE
TSADARADVQRWRARAGAILTGAGTVMADDPSMTVRLGEDTPVVPPLRVVLDARLRTLAC
ECCHHHHHHHHHHHHCCEEEECCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
RNIRQGDAPTLYLHGENVAAQSLDDAQFLAMPLHAGRFDLAAVLALLAERGINEVHVEGG
HCCCCCCCCEEEEECCCHHHCCCCCCHHEEECCCCCCHHHHHHHHHHHHCCCCEEEECCC
ATLSGALLQAGLVDELLVYMAPVLLGDTAKPLLAGLGIETMAQRAALQLLDVRQLGQDLR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LRYAPVVAG
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]