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The map label for this gene is corA [H]

Identifier: 21241373

GI number: 21241373

Start: 706323

End: 707273

Strand: Direct

Name: corA [H]

Synonym: XAC0602

Alternate gene names: 21241373

Gene position: 706323-707273 (Clockwise)

Preceding gene: 77748539

Following gene: 21241377

Centisome position: 13.65

GC content: 63.51

Gene sequence:

>951_bases
ATGGTGGACGCGGAGGATGCTTGGGCTCTTTCATCCCACAGCCGATGCATGATCACGATCCACCCGATTGCCCGAACCCA
GCACTGTTGGGTCGACTTGTGCCAGCCGAGTCCGCAAGAGCTGGCGCAAGCCGCTGAGAAAGTGGGGTTCGCCTTGCCCG
ATCGTGCGGCGATTGGCGAGATCGAATTCAGCAGCCGGGTACGCCGCCAGGGCGATGTGCTGTTTCTCAACGTGCCGCGT
TTTCAGGACGATGACGGCCCCACCGCGCCGCTGGGGTTCGCGCTGTCGCCCAGCATGCTGGTGACCTTGCGCGAGCAGCG
CATCGGCTCGTTGGAGGACTTTCCCGCGCGGCTGGAACACGCGCCCTGCCACAGCTCGGACGACCTGTTGCTGCGCATGT
TCGATCAACTGGTCGGGCGGTTGGCAGACCGGCTTGAGGCACTCGAAGCGGCAGTCACCGAGACCACGCGGCAGGTGTTC
GATAGCCCACACAAGACCAAGGATCTGGAGCGCATGTTGCACCAGGTCGGCGACATGGGCCGCCAGCTCGGCGGGCTGCA
TAGCGCCGGGCAGGGCATGCTGCGTCTGGTGACGTATCTGGATGGCACCGCGCCGGACTGGTTCGGCGCCGATGCGGCCA
AACGCATCGCCTCGCTGCACAAGGACCTGACCACCCTGAGCGAATTCCATCAGCACATGGACGACCGCATCGAGTTCCTG
CTCGACAGCGTGCTGGGCATGATCAACATCGACCAGAACAACGTGATGAAGGTGATGGCAGTGGCATCGGTGGTCGGCAT
CCCACCCACCGTGCTGGTCGGCATCTGGGGCATGAACTTCGCCTACATGCCCGAACTCAAGGGGCACGACAACTATTTCT
GGGCGCTGGGCATCATCGCGTTGAGCGTGGTGGTGCCGCTGGCGTGGTTTCGCAAGCGTGGATGGGTGTGA

Upstream 100 bases:

>100_bases
GCTGCCTTGCAGAAACCGCACGGCGATCGCATGCGTGAGCAGGCACGGCCATCGCGGCTATCGCGGCTATCGCCGATGGG
CATGCGCCGGCGTTGACGCC

Downstream 100 bases:

>100_bases
CGCATCACAGCCGAAAACCGTAGGAGCGCCCCCGGGCGCGATGTGGCGTTACCGGGAAGGCGCTCGCGCCCGGGTGCGCT
ACTACAACGTGTCGGTAGCG

Product: magnesium and cobalt transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MVDAEDAWALSSHSRCMITIHPIARTQHCWVDLCQPSPQELAQAAEKVGFALPDRAAIGEIEFSSRVRRQGDVLFLNVPR
FQDDDGPTAPLGFALSPSMLVTLREQRIGSLEDFPARLEHAPCHSSDDLLLRMFDQLVGRLADRLEALEAAVTETTRQVF
DSPHKTKDLERMLHQVGDMGRQLGGLHSAGQGMLRLVTYLDGTAPDWFGADAAKRIASLHKDLTTLSEFHQHMDDRIEFL
LDSVLGMINIDQNNVMKVMAVASVVGIPPTVLVGIWGMNFAYMPELKGHDNYFWALGIIALSVVVPLAWFRKRGWV

Sequences:

>Translated_316_residues
MVDAEDAWALSSHSRCMITIHPIARTQHCWVDLCQPSPQELAQAAEKVGFALPDRAAIGEIEFSSRVRRQGDVLFLNVPR
FQDDDGPTAPLGFALSPSMLVTLREQRIGSLEDFPARLEHAPCHSSDDLLLRMFDQLVGRLADRLEALEAAVTETTRQVF
DSPHKTKDLERMLHQVGDMGRQLGGLHSAGQGMLRLVTYLDGTAPDWFGADAAKRIASLHKDLTTLSEFHQHMDDRIEFL
LDSVLGMINIDQNNVMKVMAVASVVGIPPTVLVGIWGMNFAYMPELKGHDNYFWALGIIALSVVVPLAWFRKRGWV
>Mature_316_residues
MVDAEDAWALSSHSRCMITIHPIARTQHCWVDLCQPSPQELAQAAEKVGFALPDRAAIGEIEFSSRVRRQGDVLFLNVPR
FQDDDGPTAPLGFALSPSMLVTLREQRIGSLEDFPARLEHAPCHSSDDLLLRMFDQLVGRLADRLEALEAAVTETTRQVF
DSPHKTKDLERMLHQVGDMGRQLGGLHSAGQGMLRLVTYLDGTAPDWFGADAAKRIASLHKDLTTLSEFHQHMDDRIEFL
LDSVLGMINIDQNNVMKVMAVASVVGIPPTVLVGIWGMNFAYMPELKGHDNYFWALGIIALSVVVPLAWFRKRGWV

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=293, Percent_Identity=24.5733788395904, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 35207; Mature: 35207

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDAEDAWALSSHSRCMITIHPIARTQHCWVDLCQPSPQELAQAAEKVGFALPDRAAIGE
CCCCCCCHHHCCCCEEEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHCC
IEFSSRVRRQGDVLFLNVPRFQDDDGPTAPLGFALSPSMLVTLREQRIGSLEDFPARLEH
CHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCC
APCHSSDDLLLRMFDQLVGRLADRLEALEAAVTETTRQVFDSPHKTKDLERMLHQVGDMG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RQLGGLHSAGQGMLRLVTYLDGTAPDWFGADAAKRIASLHKDLTTLSEFHQHMDDRIEFL
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDSVLGMINIDQNNVMKVMAVASVVGIPPTVLVGIWGMNFAYMPELKGHDNYFWALGIIA
HHHHHHHEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHH
LSVVVPLAWFRKRGWV
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVDAEDAWALSSHSRCMITIHPIARTQHCWVDLCQPSPQELAQAAEKVGFALPDRAAIGE
CCCCCCCHHHCCCCEEEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHCC
IEFSSRVRRQGDVLFLNVPRFQDDDGPTAPLGFALSPSMLVTLREQRIGSLEDFPARLEH
CHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCC
APCHSSDDLLLRMFDQLVGRLADRLEALEAAVTETTRQVFDSPHKTKDLERMLHQVGDMG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RQLGGLHSAGQGMLRLVTYLDGTAPDWFGADAAKRIASLHKDLTTLSEFHQHMDDRIEFL
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDSVLGMINIDQNNVMKVMAVASVVGIPPTVLVGIWGMNFAYMPELKGHDNYFWALGIIA
HHHHHHHEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHH
LSVVVPLAWFRKRGWV
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]