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The map label for this gene is comF [H]

Identifier: 21241163

GI number: 21241163

Start: 459857

End: 460588

Strand: Direct

Name: comF [H]

Synonym: XAC0389

Alternate gene names: 21241163

Gene position: 459857-460588 (Clockwise)

Preceding gene: 21241155

Following gene: 21241180

Centisome position: 8.89

GC content: 70.22

Gene sequence:

>732_bases
GTGAGCATGCAAGAGACTGTCAACTTCAATCAGGTCCGATCGGTTTACAGATGGCCGCAGCGGGTGCTGCGACTGTTGCT
GCCGAGCCTGTGCCTGGTCTGCGCGGAGGCCGGCACGCCGGACGGCGATCTATGCCCTGCATGTCGCGCCGCCTTGCCCG
ATCATGGCCACGCCTGCCTGTGCTGCGCCACGCAGCTGTTCGCCTCCGACGCGGTGGTGCTGTGCGGGCAGTGCCTGCAG
CACCCACCAGCGCTGCAGCGGGTGCATGCCTGTTTTACCTATCGCTGGCCGGTGGATGGGCTGCTGCGGCGGTTCAAGTT
CCATCAGGACCTGGCGGCCGGCCGCCTGCTGAGCGAACTGATGGCCCGGCGCTGCGTGGGGCTGCCGCGCCCGCAGGCAT
TGGTGCCGGTAAGCCTGCACCGGCAGCGCCTGCGCCAGCGCGGTTACGACCAGGCGCTGGAGCTGGCCCGACCGCTGGGC
CGCGCGCTGCAGCTGCCGTGCCAGCCGTTGCTGCGCCGGGTTCGCGCGACCGCACCGCAATCCGAACTGGATGCGGCCGA
GCGGCAGCGCAATCTGCGCGATGCGTTCGAGGTCCGCGGCGCCTTGCCGGCGCATGTGGCCTTGGTGGACGACGTGATGA
CGACCGGCGCGACGCTCCACGCCGCGGCCAAGGCCTTGCGCAAGGCGGGTGTTCAACGGGTGGATGCCTGGGTCTGCGCG
CGGGTGCCGTGA

Upstream 100 bases:

>100_bases
ATCGAACAGCGCCTGCAGCTCTTTGCGATCCCAGTCATGGCGGAGGACAACAGACATCGGAGTTTCCTGACAGTCAGCGG
CTTGGAAGCCAGGCAGTCTG

Downstream 100 bases:

>100_bases
TCTAGCCGGCGGCCGCCGGGTGCGCGAGGCTTCGCCCGCACCCTCACCCCAGCCTCTCTCCCGCAGGAGACGGGCTCTTT
GTCCGACGGCACAGCGCGAT

Product: competence protein F

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSMQETVNFNQVRSVYRWPQRVLRLLLPSLCLVCAEAGTPDGDLCPACRAALPDHGHACLCCATQLFASDAVVLCGQCLQ
HPPALQRVHACFTYRWPVDGLLRRFKFHQDLAAGRLLSELMARRCVGLPRPQALVPVSLHRQRLRQRGYDQALELARPLG
RALQLPCQPLLRRVRATAPQSELDAAERQRNLRDAFEVRGALPAHVALVDDVMTTGATLHAAAKALRKAGVQRVDAWVCA
RVP

Sequences:

>Translated_243_residues
MSMQETVNFNQVRSVYRWPQRVLRLLLPSLCLVCAEAGTPDGDLCPACRAALPDHGHACLCCATQLFASDAVVLCGQCLQ
HPPALQRVHACFTYRWPVDGLLRRFKFHQDLAAGRLLSELMARRCVGLPRPQALVPVSLHRQRLRQRGYDQALELARPLG
RALQLPCQPLLRRVRATAPQSELDAAERQRNLRDAFEVRGALPAHVALVDDVMTTGATLHAAAKALRKAGVQRVDAWVCA
RVP
>Mature_242_residues
SMQETVNFNQVRSVYRWPQRVLRLLLPSLCLVCAEAGTPDGDLCPACRAALPDHGHACLCCATQLFASDAVVLCGQCLQH
PPALQRVHACFTYRWPVDGLLRRFKFHQDLAAGRLLSELMARRCVGLPRPQALVPVSLHRQRLRQRGYDQALELARPLGR
ALQLPCQPLLRRVRATAPQSELDAAERQRNLRDAFEVRGALPAHVALVDDVMTTGATLHAAAKALRKAGVQRVDAWVCAR
VP

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=226, Percent_Identity=36.283185840708, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 26958; Mature: 26827

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
5.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure 
SMQETVNFNQVRSVYRWPQRVLRLLLPSLCLVCAEAGTPDGDLCPACRAALPDHGHACL
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHHH
CCATQLFASDAVVLCGQCLQHPPALQRVHACFTYRWPVDGLLRRFKFHQDLAAGRLLSEL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MARRCVGLPRPQALVPVSLHRQRLRQRGYDQALELARPLGRALQLPCQPLLRRVRATAPQ
HHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCH
SELDAAERQRNLRDAFEVRGALPAHVALVDDVMTTGATLHAAAKALRKAGVQRVDAWVCA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RVP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]