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The map label for this gene is frp [H]

Identifier: 21241095

GI number: 21241095

Start: 382489

End: 383586

Strand: Direct

Name: frp [H]

Synonym: XAC0321

Alternate gene names: 21241095

Gene position: 382489-383586 (Clockwise)

Preceding gene: 77748522

Following gene: 21241096

Centisome position: 7.39

GC content: 65.66

Gene sequence:

>1098_bases
TTGAGCCAGTTGTTCTCCCCCATCGCCTTCGGTCCGCTTGCGCTCGCCAACCGGATTGTCATTGCGCCGATGTGCCAGTA
CTCGGCACAGAACGGCCGCGCCAGCGATTGGCACCGCATCCATCTGGGCACGTTGTCGCAATCCGGCGCCGGCTTGCTGA
TTCTCGAAGCGGCCGCAGTGGTACCGGAAGGGCGCATCAGTTACGCCGATCTTGGGTTGTACGATGATGCGACCGAGCAG
GCGCTGGCCGAGGTACTGCAATCGGTACGACGCTGGTCGCCGATGCCGATCGGCATCCAGCTGGCGCATGCCGGGCGCAA
GGCCTCGACCGATCTGCCGTGGAAAGGCGGCGAGGCCATCGCGCCCGACCACGCGCATGGCTGGCAGACCGTGTCTGCAT
CGGCGCTGCCGTTCCGCCAGGGACAGCCGGCGCCGCAGACACTGGATGAGGCGGGAATCGATGCCGTGGTGGACGCCTTC
GTCGCATCGGCAACGCGTGCCGAACGGCTGGGCCTGGAGTTGATCGAACTGCACGCCGCGCATGGTTATCTGATGCATCA
ATTCCTGTCGCCGCTGAGTAACCAGCGCAGCGATGCATATGGCGGTTCGCTGGAAAATCGCATGCGGCTGACGCTGCGCA
TCTTCGATGCGGTGCGTGCGGCAGTGTCGGAAAAAATCGCCGTTGGCGTGCGTATCTCGGCCACCGACTGGGTCGAAGGC
GGGTGGGATGTGCAGCAGAGCATCGCCTTGTCGCAGGCGCTGGATGCACGCGGTGCGCATTACATCCATGTCTCTAGCGG
CGGGCTCGATCCACGCCAGCAGATTCCGCTGCAGGCGGGCTATCAGATTCCGTTCGCGCAGGAGATCCGCGCGCAGGTGA
ACACGCCGGTGATTGGCGTAGGCTTGATCACCGAGCCGGCGCAGGCCGAGGCGATTCTGCAAGAAGGCCAGGCCGATGCG
ATCGCGCTGGCGCGTGGCATCCTGTACGACCCGCGCTGGCCGTGGCATGCCGCCGCGGCGCTGGGCGCCTCGGTCACTCC
GGCACCGCAATACCTGCGTTGCGAACCGCGCGATGCGCGGGGCGTGTTCGCCAACTGA

Upstream 100 bases:

>100_bases
CCAGTGCACGCTCTGCATGACGCAGTGATCCATCGCAGCGGTTGTGCCGGCGCGCGCGGCGCAGTGCAATAAGCACCCCA
TGTCAGCTGTGGATGCCGCC

Downstream 100 bases:

>100_bases
TTTGCACCTGACGTCATACCGAACAAGGACACCGCATGCCGATAGGATTTCTGGGCTTGGGCACGATGGGCCTGCCGATG
GCGCACAACCTGCTGCGTGG

Product: FMN oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSQLFSPIAFGPLALANRIVIAPMCQYSAQNGRASDWHRIHLGTLSQSGAGLLILEAAAVVPEGRISYADLGLYDDATEQ
ALAEVLQSVRRWSPMPIGIQLAHAGRKASTDLPWKGGEAIAPDHAHGWQTVSASALPFRQGQPAPQTLDEAGIDAVVDAF
VASATRAERLGLELIELHAAHGYLMHQFLSPLSNQRSDAYGGSLENRMRLTLRIFDAVRAAVSEKIAVGVRISATDWVEG
GWDVQQSIALSQALDARGAHYIHVSSGGLDPRQQIPLQAGYQIPFAQEIRAQVNTPVIGVGLITEPAQAEAILQEGQADA
IALARGILYDPRWPWHAAAALGASVTPAPQYLRCEPRDARGVFAN

Sequences:

>Translated_365_residues
MSQLFSPIAFGPLALANRIVIAPMCQYSAQNGRASDWHRIHLGTLSQSGAGLLILEAAAVVPEGRISYADLGLYDDATEQ
ALAEVLQSVRRWSPMPIGIQLAHAGRKASTDLPWKGGEAIAPDHAHGWQTVSASALPFRQGQPAPQTLDEAGIDAVVDAF
VASATRAERLGLELIELHAAHGYLMHQFLSPLSNQRSDAYGGSLENRMRLTLRIFDAVRAAVSEKIAVGVRISATDWVEG
GWDVQQSIALSQALDARGAHYIHVSSGGLDPRQQIPLQAGYQIPFAQEIRAQVNTPVIGVGLITEPAQAEAILQEGQADA
IALARGILYDPRWPWHAAAALGASVTPAPQYLRCEPRDARGVFAN
>Mature_364_residues
SQLFSPIAFGPLALANRIVIAPMCQYSAQNGRASDWHRIHLGTLSQSGAGLLILEAAAVVPEGRISYADLGLYDDATEQA
LAEVLQSVRRWSPMPIGIQLAHAGRKASTDLPWKGGEAIAPDHAHGWQTVSASALPFRQGQPAPQTLDEAGIDAVVDAFV
ASATRAERLGLELIELHAAHGYLMHQFLSPLSNQRSDAYGGSLENRMRLTLRIFDAVRAAVSEKIAVGVRISATDWVEGG
WDVQQSIALSQALDARGAHYIHVSSGGLDPRQQIPLQAGYQIPFAQEIRAQVNTPVIGVGLITEPAQAEAILQEGQADAI
ALARGILYDPRWPWHAAAALGASVTPAPQYLRCEPRDARGVFAN

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=347, Percent_Identity=29.6829971181556, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789463, Length=331, Percent_Identity=24.773413897281, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=265, Percent_Identity=32.4528301886792, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17559802, Length=259, Percent_Identity=30.8880308880309, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17564188, Length=249, Percent_Identity=30.5220883534137, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17559804, Length=249, Percent_Identity=30.5220883534137, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17565138, Length=214, Percent_Identity=30.8411214953271, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17540738, Length=260, Percent_Identity=28.0769230769231, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17566914, Length=119, Percent_Identity=32.7731092436975, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321973, Length=246, Percent_Identity=29.6747967479675, Blast_Score=89, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6325086, Length=250, Percent_Identity=27.2, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39113; Mature: 38981

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLFSPIAFGPLALANRIVIAPMCQYSAQNGRASDWHRIHLGTLSQSGAGLLILEAAAV
CCCHHCHHHHHHHHHHCCEEEEEHHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEHHHH
VPEGRISYADLGLYDDATEQALAEVLQSVRRWSPMPIGIQLAHAGRKASTDLPWKGGEAI
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCC
APDHAHGWQTVSASALPFRQGQPAPQTLDEAGIDAVVDAFVASATRAERLGLELIELHAA
CCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
HGYLMHQFLSPLSNQRSDAYGGSLENRMRLTLRIFDAVRAAVSEKIAVGVRISATDWVEG
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCC
GWDVQQSIALSQALDARGAHYIHVSSGGLDPRQQIPLQAGYQIPFAQEIRAQVNTPVIGV
CCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCCCCCHHHHHHHHCCCCEEEE
GLITEPAQAEAILQEGQADAIALARGILYDPRWPWHAAAALGASVTPAPQYLRCEPRDAR
EECCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCEECCCCCCC
GVFAN
CCCCC
>Mature Secondary Structure 
SQLFSPIAFGPLALANRIVIAPMCQYSAQNGRASDWHRIHLGTLSQSGAGLLILEAAAV
CCHHCHHHHHHHHHHCCEEEEEHHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEHHHH
VPEGRISYADLGLYDDATEQALAEVLQSVRRWSPMPIGIQLAHAGRKASTDLPWKGGEAI
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCC
APDHAHGWQTVSASALPFRQGQPAPQTLDEAGIDAVVDAFVASATRAERLGLELIELHAA
CCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
HGYLMHQFLSPLSNQRSDAYGGSLENRMRLTLRIFDAVRAAVSEKIAVGVRISATDWVEG
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCC
GWDVQQSIALSQALDARGAHYIHVSSGGLDPRQQIPLQAGYQIPFAQEIRAQVNTPVIGV
CCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCCCCCHHHHHHHHCCCCEEEE
GLITEPAQAEAILQEGQADAIALARGILYDPRWPWHAAAALGASVTPAPQYLRCEPRDAR
EECCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCEECCCCCCC
GVFAN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA