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The map label for this gene is mhpD

Identifier: 21240935

GI number: 21240935

Start: 199558

End: 200379

Strand: Direct

Name: mhpD

Synonym: XAC0161

Alternate gene names: NA

Gene position: 199558-200379 (Clockwise)

Preceding gene: 21240932

Following gene: 21240936

Centisome position: 3.86

GC content: 65.45

Gene sequence:

>822_bases
TTGAGCAACGACGCCGCCACTCCGCCATCGTCCACACCCGCGCTGTCCGCCATTGCCCAGCGATTTGTGGAAGCACGCCG
TGCAGGGGCATCGCTGCCTGACTTTCCCGGGCAAATCCCCGACGATCTGGTCACCGCCTACCAGGTGCAGGACATCGCCA
TCAGCCAGTGGCACGACCACGTCGTCGGCTGGAAGGTGGGGTACATCGCCGCCGAGCGCCGCGACGCGTCCGGCGACGAG
CGTCTGCTCGGCCCGATCTTCTCTCGGAAGGTCTGGAATGCTACCGGTGGAACAACCGAGTTCCCGATCTTTGTCGGCGG
CTTCGGCGCAGTGGAAGCCGAATATGTCCTGATGCTCGGTGCCGATGCCCCGGCCGATCAGACCCACTTCACCCCGGAGC
AGGCGGCAGAGTTGCCGGCCACGTTGTTCATCGGAGTGGAAATCGCCAGCAGCCCGCTGGCCACCATCAACCAGTTGGGC
CCGCGGGTGGTGATTTCGGACTTCGGCAACAACAACGGCCTGATTCTGGGCCCGGAAGTGACCGATTGGCTGGCGCGCGA
CGAGGCTGCGCTCACTGCCCAGACGCTGATCGACGAAAAGGTGGTTGGCACCGGTGGGGCCACCACGTTGCCGGGCGGGC
TGCGCGCGGCCTACGCATTCGCGCTCAGCCGTTCGGCACAGCGCGGGCGTCCGCTCAAGCGCGGTGATCTGATTGCCACC
GGCAATGCCACCGGTATCCACGACATCGAAGTGGGGCAGCGTGCCCTGATTCGCTTCGCCGGCATCGGCGATATTTCCTG
TACGGCTGTGTCCGCCAGTTGA

Upstream 100 bases:

>100_bases
TGCCGCAGTGCACATTGCCAATGACACCGGTTTACCATATACAGCACACCGTGCCGCTGTCGATTGGCAGTGCAACAAAA
CACCTATCGGGGAGACACCC

Downstream 100 bases:

>100_bases
CGGCGGTCCCCGTGACCAGACGCTTGGGAGGGCGCCAATGATCACACGCAGACATTTTCTCGGTGCCGGGCTCGGCGCCG
CTGCTGCCGCCCCCTGGTTG

Product: 2-keto-4-pentenoate hydratase

Products: 2-oxopent-4-enoate; H2O

Alternate protein names: 2-Keto-4-Pentenoate Hydratase-Like Protein; Fumarylacetoacetate Hydrolase; 2-Keto-4-Pentenoate Hydratase Family Protein; Hydratase/Decarboxylase

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSNDAATPPSSTPALSAIAQRFVEARRAGASLPDFPGQIPDDLVTAYQVQDIAISQWHDHVVGWKVGYIAAERRDASGDE
RLLGPIFSRKVWNATGGTTEFPIFVGGFGAVEAEYVLMLGADAPADQTHFTPEQAAELPATLFIGVEIASSPLATINQLG
PRVVISDFGNNNGLILGPEVTDWLARDEAALTAQTLIDEKVVGTGGATTLPGGLRAAYAFALSRSAQRGRPLKRGDLIAT
GNATGIHDIEVGQRALIRFAGIGDISCTAVSAS

Sequences:

>Translated_273_residues
MSNDAATPPSSTPALSAIAQRFVEARRAGASLPDFPGQIPDDLVTAYQVQDIAISQWHDHVVGWKVGYIAAERRDASGDE
RLLGPIFSRKVWNATGGTTEFPIFVGGFGAVEAEYVLMLGADAPADQTHFTPEQAAELPATLFIGVEIASSPLATINQLG
PRVVISDFGNNNGLILGPEVTDWLARDEAALTAQTLIDEKVVGTGGATTLPGGLRAAYAFALSRSAQRGRPLKRGDLIAT
GNATGIHDIEVGQRALIRFAGIGDISCTAVSAS
>Mature_272_residues
SNDAATPPSSTPALSAIAQRFVEARRAGASLPDFPGQIPDDLVTAYQVQDIAISQWHDHVVGWKVGYIAAERRDASGDER
LLGPIFSRKVWNATGGTTEFPIFVGGFGAVEAEYVLMLGADAPADQTHFTPEQAAELPATLFIGVEIASSPLATINQLGP
RVVISDFGNNNGLILGPEVTDWLARDEAALTAQTLIDEKVVGTGGATTLPGGLRAAYAFALSRSAQRGRPLKRGDLIATG
NATGIHDIEVGQRALIRFAGIGDISCTAVSAS

Specific function: Unknown

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.80

Molecular weight: Translated: 28593; Mature: 28462

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDAATPPSSTPALSAIAQRFVEARRAGASLPDFPGQIPDDLVTAYQVQDIAISQWHDH
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VVGWKVGYIAAERRDASGDERLLGPIFSRKVWNATGGTTEFPIFVGGFGAVEAEYVLMLG
HCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEECCEEECCCCCCCEEEEEEEC
ADAPADQTHFTPEQAAELPATLFIGVEIASSPLATINQLGPRVVISDFGNNNGLILGPEV
CCCCCCCCCCCHHHHHHCCEEEEEEEEECCCCHHHHHHCCCEEEEEECCCCCCEEECCCH
TDWLARDEAALTAQTLIDEKVVGTGGATTLPGGLRAAYAFALSRSAQRGRPLKRGDLIAT
HHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEE
GNATGIHDIEVGQRALIRFAGIGDISCTAVSAS
CCCCCCEEHHHHHHHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure 
SNDAATPPSSTPALSAIAQRFVEARRAGASLPDFPGQIPDDLVTAYQVQDIAISQWHDH
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VVGWKVGYIAAERRDASGDERLLGPIFSRKVWNATGGTTEFPIFVGGFGAVEAEYVLMLG
HCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEECCEEECCCCCCCEEEEEEEC
ADAPADQTHFTPEQAAELPATLFIGVEIASSPLATINQLGPRVVISDFGNNNGLILGPEV
CCCCCCCCCCCHHHHHHCCEEEEEEEEECCCCHHHHHHCCCEEEEEECCCCCCEEECCCH
TDWLARDEAALTAQTLIDEKVVGTGGATTLPGGLRAAYAFALSRSAQRGRPLKRGDLIAT
HHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEE
GNATGIHDIEVGQRALIRFAGIGDISCTAVSAS
CCCCCCEEHHHHHHHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-hydroxy-2-oxopentanoate

Specific reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA