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The map label for this gene is tldD [C]

Identifier: 21240894

GI number: 21240894

Start: 139834

End: 141168

Strand: Reverse

Name: tldD [C]

Synonym: XAC0120

Alternate gene names: 21240894

Gene position: 141168-139834 (Counterclockwise)

Preceding gene: 21240895

Following gene: 77748508

Centisome position: 2.73

GC content: 63.52

Gene sequence:

>1335_bases
ATGAGCATCCTTACCGAAGCGCAGGCCAAGGCCATCCTGGACAAGGTCATCAAGCTGTCCAAGGCCGACGAGTGCACCGC
CACCCTCACCGGCTCGATCGACGGCAATATCCGTTTTGCGCTCAACAACGTGTCCACCAGCGGCATCGTCGACAACACCG
ACCTGCAGGTGCAGGTGGCGTTCGGCAAGCGGGTGGGCGTGGCCACCATCAACGAGTTCGACGACGCCTCGCTGGAGCGC
GTGGTGCGCCGTGCCGAAGACCTGGCCAAGCTGGCACCGGAAAACCCGGAATTCATGCCGGCGGTCGACAAGCAGACCTA
CAGGCCCAGCCCCACCTTCAGCGAATCCACGGCAGCGATCGATCCGGCGTTCCGCGCGCAGGTGGCCGCCGATTCGATCG
CCCCGTGCAAGGGCAAGGGCCTGATCGCGGCCGGCTTCCTCGAAGACGGCCAGAGCTTTACCGCTTTTGCCAACAGCAAG
GGCAACTTTGGCTATCAGCGCGGTGCGCGCTTCGACTACACCTGCACCGTGCGCACCGAAGATGGCCGCGGCTCGGGCTG
GGTGGGCCGCAATCTGAAGGATGCCGCCGACTTCAAGGCCGAGCAGGACATCCGCATCGCGATGCGCAAGGCCAGCGATT
CGGCCGAAGCCAAGGCGCTGGAGCCGGGCAAGTACACGGTGATCCTGGAGCCGGCGGCGGCCGCAGGCCTGATCTCCTTC
ATGATGAATTTCTTCGACGCGCGCCGCGCCGACGAAGGCCGCAGCTTCCTGTCCAAGAAAGGTGGCGGCAACAAGCTCGG
CGAACAGGTCTACGACCCGCGCGTGAACATCACCGCCGACCCGTGGGACCCGCGTGCGGCAGTGATGCCGTGGGACGAAG
AAGGCCTGCCGCGCGAAAAGATGGCCATCGTGGAAAACGGCAAGATCGCCAACCTGCAGTACTCGCGCTTCTGGGCGCAG
AAAAACGGCAAGCGTGCGGTCGGCGAGCCGGGCAATCTGTTGATGGCCGGCGGCGACAAGAACATCGCCGAGCTGGTGCG
TGGCACCGAGAAAGGCATTCTGGTCACGCGCACCTGGTACATCCGCATGGTCGACCCGCAGACCGTGCTGCTGACCGGGC
TCACCCGCGATGGCACCTTCTACATCGAGAACGGCCAGATCAAATATCCGGTGAAGAATTTCCGCTTCAACGAATCGCCG
GTGATCATGCTCAACAACATCGACGAATTGGGCAAGCCGGTGCGCGTGGCCGGCGACGAATCCAACTTCGTGATGATGAT
TCCGCCGATGCGGCTGCGGGACTTCACGTTTACCTCGTTGTCGGATGCGGTGTGA

Upstream 100 bases:

>100_bases
GCCAGGTCTCGGCGGTCTCGCACGGTTCGTCCACCGCCCGCTTCGATGGCATCAACGTCATCAGCACCGCCCGCTCGCTC
GGCTGACAGGAGAAACCCAC

Downstream 100 bases:

>100_bases
CTGAAGACCGGGATTGGGGAGTCGGGAGTCGGGAGTCGGAGAGCGCAGCAAGCTCTCCGCAGCCTGATGTTTTTCCTGCA
CCTCCTGTTTCCGGTCCACG

Product: TldD protein

Products: NA

Alternate protein names: PmbA Protein; TldD/PmbA Family Protein; Zn-Dependent Protease; Peptidase PmbA; Modulator Of DNA Gyrase; TldD/PmbA Family; Zinc-Dependent Protease TldD/PmbA Family; CalR5 Protein; TldD Protein; Zinc-Dependent Protease; Modulator Of DNA Gyrase Protein; Zn-Dependent Protease-Like Protein; TldE-Like Protein; Protein For Maturation Of Antibiotic MccB; LOW QUALITY PROTEIN CalR5 Protein; TldE/PmbA-Like Protein; Protease PmbA; Modulator Of DNA Gyrase Protein TldD; Inactivated Zn-Dependent Peptidase PMBA Ortholog; PmbA-Related Protein; Zinc Protease PmbA; PmbA/TldD Protein; Microcin-Processing Peptidase PmbA; Maturation Protein; Zn-Dependent Protease Modulator Of DNA Gyrase; Regulatory Protease; Protein PmbA; DNA Gyrase Modulator Family Protein

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSILTEAQAKAILDKVIKLSKADECTATLTGSIDGNIRFALNNVSTSGIVDNTDLQVQVAFGKRVGVATINEFDDASLER
VVRRAEDLAKLAPENPEFMPAVDKQTYRPSPTFSESTAAIDPAFRAQVAADSIAPCKGKGLIAAGFLEDGQSFTAFANSK
GNFGYQRGARFDYTCTVRTEDGRGSGWVGRNLKDAADFKAEQDIRIAMRKASDSAEAKALEPGKYTVILEPAAAAGLISF
MMNFFDARRADEGRSFLSKKGGGNKLGEQVYDPRVNITADPWDPRAAVMPWDEEGLPREKMAIVENGKIANLQYSRFWAQ
KNGKRAVGEPGNLLMAGGDKNIAELVRGTEKGILVTRTWYIRMVDPQTVLLTGLTRDGTFYIENGQIKYPVKNFRFNESP
VIMLNNIDELGKPVRVAGDESNFVMMIPPMRLRDFTFTSLSDAV

Sequences:

>Translated_444_residues
MSILTEAQAKAILDKVIKLSKADECTATLTGSIDGNIRFALNNVSTSGIVDNTDLQVQVAFGKRVGVATINEFDDASLER
VVRRAEDLAKLAPENPEFMPAVDKQTYRPSPTFSESTAAIDPAFRAQVAADSIAPCKGKGLIAAGFLEDGQSFTAFANSK
GNFGYQRGARFDYTCTVRTEDGRGSGWVGRNLKDAADFKAEQDIRIAMRKASDSAEAKALEPGKYTVILEPAAAAGLISF
MMNFFDARRADEGRSFLSKKGGGNKLGEQVYDPRVNITADPWDPRAAVMPWDEEGLPREKMAIVENGKIANLQYSRFWAQ
KNGKRAVGEPGNLLMAGGDKNIAELVRGTEKGILVTRTWYIRMVDPQTVLLTGLTRDGTFYIENGQIKYPVKNFRFNESP
VIMLNNIDELGKPVRVAGDESNFVMMIPPMRLRDFTFTSLSDAV
>Mature_443_residues
SILTEAQAKAILDKVIKLSKADECTATLTGSIDGNIRFALNNVSTSGIVDNTDLQVQVAFGKRVGVATINEFDDASLERV
VRRAEDLAKLAPENPEFMPAVDKQTYRPSPTFSESTAAIDPAFRAQVAADSIAPCKGKGLIAAGFLEDGQSFTAFANSKG
NFGYQRGARFDYTCTVRTEDGRGSGWVGRNLKDAADFKAEQDIRIAMRKASDSAEAKALEPGKYTVILEPAAAAGLISFM
MNFFDARRADEGRSFLSKKGGGNKLGEQVYDPRVNITADPWDPRAAVMPWDEEGLPREKMAIVENGKIANLQYSRFWAQK
NGKRAVGEPGNLLMAGGDKNIAELVRGTEKGILVTRTWYIRMVDPQTVLLTGLTRDGTFYIENGQIKYPVKNFRFNESPV
IMLNNIDELGKPVRVAGDESNFVMMIPPMRLRDFTFTSLSDAV

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48642; Mature: 48511

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILTEAQAKAILDKVIKLSKADECTATLTGSIDGNIRFALNNVSTSGIVDNTDLQVQVA
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCCEEECCCEEEEEE
FGKRVGVATINEFDDASLERVVRRAEDLAKLAPENPEFMPAVDKQTYRPSPTFSESTAAI
ECCEECEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DPAFRAQVAADSIAPCKGKGLIAAGFLEDGQSFTAFANSKGNFGYQRGARFDYTCTVRTE
CHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEEEEEC
DGRGSGWVGRNLKDAADFKAEQDIRIAMRKASDSAEAKALEPGKYTVILEPAAAAGLISF
CCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCCCCCCEEECCCCEEEEECCHHHHHHHHH
MMNFFDARRADEGRSFLSKKGGGNKLGEQVYDPRVNITADPWDPRAAVMPWDEEGLPREK
HHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCCCEEECCCCCCCCCHHH
MAIVENGKIANLQYSRFWAQKNGKRAVGEPGNLLMAGGDKNIAELVRGTEKGILVTRTWY
EEEEECCEEEEEEHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHCCCCCCEEEEEEEE
IRMVDPQTVLLTGLTRDGTFYIENGQIKYPVKNFRFNESPVIMLNNIDELGKPVRVAGDE
EEEECCCEEEEEEECCCCEEEEECCEEEECHHHCCCCCCCEEEECCHHHHCCCEEEECCC
SNFVMMIPPMRLRDFTFTSLSDAV
CCEEEEECCCCCCCCEECHHHCCC
>Mature Secondary Structure 
SILTEAQAKAILDKVIKLSKADECTATLTGSIDGNIRFALNNVSTSGIVDNTDLQVQVA
CCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCCEEECCCEEEEEE
FGKRVGVATINEFDDASLERVVRRAEDLAKLAPENPEFMPAVDKQTYRPSPTFSESTAAI
ECCEECEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DPAFRAQVAADSIAPCKGKGLIAAGFLEDGQSFTAFANSKGNFGYQRGARFDYTCTVRTE
CHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEEEEEC
DGRGSGWVGRNLKDAADFKAEQDIRIAMRKASDSAEAKALEPGKYTVILEPAAAAGLISF
CCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCCCCCCEEECCCCEEEEECCHHHHHHHHH
MMNFFDARRADEGRSFLSKKGGGNKLGEQVYDPRVNITADPWDPRAAVMPWDEEGLPREK
HHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCCCEEECCCCCCCCCHHH
MAIVENGKIANLQYSRFWAQKNGKRAVGEPGNLLMAGGDKNIAELVRGTEKGILVTRTWY
EEEEECCEEEEEEHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHCCCCCCEEEEEEEE
IRMVDPQTVLLTGLTRDGTFYIENGQIKYPVKNFRFNESPVIMLNNIDELGKPVRVAGDE
EEEECCCEEEEEEECCCCEEEEECCEEEECHHHCCCCCCCEEEECCHHHHCCCEEEECCC
SNFVMMIPPMRLRDFTFTSLSDAV
CCEEEEECCCCCCCCEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA