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The map label for this gene is xerD [H]

Identifier: 161485706

GI number: 161485706

Start: 4210642

End: 4211613

Strand: Reverse

Name: xerD [H]

Synonym: XAC3551

Alternate gene names: 161485706

Gene position: 4211613-4210642 (Counterclockwise)

Preceding gene: 21244278

Following gene: 21244275

Centisome position: 81.38

GC content: 67.9

Gene sequence:

>972_bases
ATGTCTGCCAGCAGCCCCGCCGAACGCCGCCAACTAGCCCGCCACCTGCCGCCGGTGCAGCCGGCTGATGCCAGCGTCAT
CGAACGGTTTCTCGACCGGTTCTGGGCCGAGCAGGGCGTGGCGCGGCAGACCCTGGAGAGTTATCGGCGCGATCTGGAAG
GGCTGGCGCGTTGGCGCGATGGCGCTGGTGGCGGCTTGCTGGGCATCGACCGTGCCGCCCTGTTCGACTATCTGCGCTGG
CGCACCCGGGCGAATTATTCTCCGCGCAGCACGGCGCGGCTGTTGTCGACCTTGCGTGCGTTCTACGGACTGTGCCTGCG
CGATGGCGCGCGCAGCGACGACCCCACCGCCTTGATCGACCCGCCGCACCTGCCACGCTCGCTGCCAAAGGCCTTGACCG
AAAGTCAGATCGAGGCCCTGCTGGCTGCGCCGGACCTTGACACACCTGCGGGCCTGCGCGATCGCGCCATGCTGGAACTG
ATGTACGCCGCGGGCCTGCGTGTGAGCGAGCTGGTCAACCTGCCGGCAGTGGGGGTGAACCTGCGCCAGGGCGTGTTGCG
GGTGACCGGCAAGGGCAGCAAGGACCGGCTGGTGCCGCTGGGCGAGGAATCCCAGCATTGGTTGGAGCGTTACCTGCGCG
AGGCGCGCCCGCTGCTGGCCGCGAACAAGCCGGTGGCAGCGGTGGACGGGCAGGTGCCGTTGTTCATCGATGTCTCCCGC
CAACCGCTCAGTCGTCAACAATTCTGGGCGCTGGTCAAACGCTACGCAGCGGTGGCCGGCATCGACCCGGCCACGGTCAG
CCCGCACGGGCTGCGCCACAGCTTTGCCACCCATCTGCTCAACCACGGCGCCGATCTGCGCGCGTTGCAGATGCTGCTGG
GCCACAGCTCGTTGTCGACCACCCAGATCTATACGCTGGTGGCGCGCCAGCATCTGCAGAAACTGCACGCCAGTCATCAT
CCGCGTGGTTAG

Upstream 100 bases:

>100_bases
GACGCGCACAGGTCCTAGCCCGCGCGCGCAGGCAAGGCACCTACCGGCAACCCGCACTGCGTCCGCTCTCAAAACGCGCG
CCGCGTTTTATGCTGTGGCG

Downstream 100 bases:

>100_bases
TCCGCGCGGCGCCTCGCCATGGGCGTGCGCGCTGGCGACGCGCCGGTCGCGGTTGCGGTAGAGCTGCGACCAGGCCAATC
GCCTGCCCGCGGCCGCACCA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSASSPAERRQLARHLPPVQPADASVIERFLDRFWAEQGVARQTLESYRRDLEGLARWRDGAGGGLLGIDRAALFDYLRW
RTRANYSPRSTARLLSTLRAFYGLCLRDGARSDDPTALIDPPHLPRSLPKALTESQIEALLAAPDLDTPAGLRDRAMLEL
MYAAGLRVSELVNLPAVGVNLRQGVLRVTGKGSKDRLVPLGEESQHWLERYLREARPLLAANKPVAAVDGQVPLFIDVSR
QPLSRQQFWALVKRYAAVAGIDPATVSPHGLRHSFATHLLNHGADLRALQMLLGHSSLSTTQIYTLVARQHLQKLHASHH
PRG

Sequences:

>Translated_323_residues
MSASSPAERRQLARHLPPVQPADASVIERFLDRFWAEQGVARQTLESYRRDLEGLARWRDGAGGGLLGIDRAALFDYLRW
RTRANYSPRSTARLLSTLRAFYGLCLRDGARSDDPTALIDPPHLPRSLPKALTESQIEALLAAPDLDTPAGLRDRAMLEL
MYAAGLRVSELVNLPAVGVNLRQGVLRVTGKGSKDRLVPLGEESQHWLERYLREARPLLAANKPVAAVDGQVPLFIDVSR
QPLSRQQFWALVKRYAAVAGIDPATVSPHGLRHSFATHLLNHGADLRALQMLLGHSSLSTTQIYTLVARQHLQKLHASHH
PRG
>Mature_322_residues
SASSPAERRQLARHLPPVQPADASVIERFLDRFWAEQGVARQTLESYRRDLEGLARWRDGAGGGLLGIDRAALFDYLRWR
TRANYSPRSTARLLSTLRAFYGLCLRDGARSDDPTALIDPPHLPRSLPKALTESQIEALLAAPDLDTPAGLRDRAMLELM
YAAGLRVSELVNLPAVGVNLRQGVLRVTGKGSKDRLVPLGEESQHWLERYLREARPLLAANKPVAAVDGQVPLFIDVSRQ
PLSRQQFWALVKRYAAVAGIDPATVSPHGLRHSFATHLLNHGADLRALQMLLGHSSLSTTQIYTLVARQHLQKLHASHHP
RG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=301, Percent_Identity=51.1627906976744, Blast_Score=290, Evalue=7e-80,
Organism=Escherichia coli, GI1790244, Length=297, Percent_Identity=34.6801346801347, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1790768, Length=183, Percent_Identity=30.0546448087432, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790767, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35795; Mature: 35664

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASSPAERRQLARHLPPVQPADASVIERFLDRFWAEQGVARQTLESYRRDLEGLARWRD
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
GAGGGLLGIDRAALFDYLRWRTRANYSPRSTARLLSTLRAFYGLCLRDGARSDDPTALID
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECC
PPHLPRSLPKALTESQIEALLAAPDLDTPAGLRDRAMLELMYAAGLRVSELVNLPAVGVN
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCH
LRQGVLRVTGKGSKDRLVPLGEESQHWLERYLREARPLLAANKPVAAVDGQVPLFIDVSR
HHHCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCC
QPLSRQQFWALVKRYAAVAGIDPATVSPHGLRHSFATHLLNHGADLRALQMLLGHSSLST
CCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHH
TQIYTLVARQHLQKLHASHHPRG
HHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SASSPAERRQLARHLPPVQPADASVIERFLDRFWAEQGVARQTLESYRRDLEGLARWRD
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
GAGGGLLGIDRAALFDYLRWRTRANYSPRSTARLLSTLRAFYGLCLRDGARSDDPTALID
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECC
PPHLPRSLPKALTESQIEALLAAPDLDTPAGLRDRAMLELMYAAGLRVSELVNLPAVGVN
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCH
LRQGVLRVTGKGSKDRLVPLGEESQHWLERYLREARPLLAANKPVAAVDGQVPLFIDVSR
HHHCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCC
QPLSRQQFWALVKRYAAVAGIDPATVSPHGLRHSFATHLLNHGADLRALQMLLGHSSLST
CCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHH
TQIYTLVARQHLQKLHASHHPRG
HHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]