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The map label for this gene is 57238723

Identifier: 57238723

GI number: 57238723

Start: 1346482

End: 1347135

Strand: Direct

Name: 57238723

Synonym: CJE1441

Alternate gene names: NA

Gene position: 1346482-1347135 (Clockwise)

Preceding gene: 57238176

Following gene: 57238724

Centisome position: 75.74

GC content: 29.36

Gene sequence:

>654_bases
ATGAAAAAACTTATAATCTTATCTTTATTATCCACTCTAGCTTTTGCTGATTATACACAATACAAACCAAGCGAAGATTT
TGCCAAGTATTTTACTAAACAAAACTGCTCACAAGTTTTGGATAAATTTTATTATATTAATTGTTATGATTATTCTTTAA
AAGGCACTAAAGCCGTAGCTTATAGATTAGAAGCGGATAATTTAAAAGGCGAACAAATCAAAAAACGCCCACGCTTTGAA
GATGATACAAATATTCCTAAAAAATACCGCACCACATGGAGTGATTATAAAAACAGCGGTTACGACAGGGGACACACTCT
TTCTAATGCTTCAATGAGAAAAACAACTCAAGCTCAAAGAAGCACTTTTTTAATGAGCAACATTACTCCACAAAATCCAC
AAATCAATCAAAGAGTTTGGAATAAAATTGAAAAAAGAGAAAGACAAGTAGCTTTAAAGCTTGGAAGTTTAGAAGTTTTA
AATTTGGTTAATTATGACAATAATCCACAAAGAATAAAAAACAATATTGCTATTCCAAGCTCTTACACTAAGATTTTAAA
AGGTGATAATTTTAAAGAATGTTACCAAGTGCCTAATCACGATGTAGAAAATGAGAATTTAAGAATATATAAAGTAAAAT
GTGACAATTTTTAA

Upstream 100 bases:

>100_bases
TAAAAAAAAGTGCTTTAAAAAATTATGTATTTATAGGTGTAGTGGTTTGCTCTTGTAATGCAAAGATATTTTTAAATCAA
ATTGAAAGGGTATGAAACAA

Downstream 100 bases:

>100_bases
TTAAAAAGGAGTAAAAATGGAAATTGCAGGACTTGTGTATTTTATCTTTGCTGTTGTATGTGCTTTTGAACTTTCTTATG
ATGCTAAACAAAGAAATATG

Product: DNA/RNA non-specific endonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKKLIILSLLSTLAFADYTQYKPSEDFAKYFTKQNCSQVLDKFYYINCYDYSLKGTKAVAYRLEADNLKGEQIKKRPRFE
DDTNIPKKYRTTWSDYKNSGYDRGHTLSNASMRKTTQAQRSTFLMSNITPQNPQINQRVWNKIEKRERQVALKLGSLEVL
NLVNYDNNPQRIKNNIAIPSSYTKILKGDNFKECYQVPNHDVENENLRIYKVKCDNF

Sequences:

>Translated_217_residues
MKKLIILSLLSTLAFADYTQYKPSEDFAKYFTKQNCSQVLDKFYYINCYDYSLKGTKAVAYRLEADNLKGEQIKKRPRFE
DDTNIPKKYRTTWSDYKNSGYDRGHTLSNASMRKTTQAQRSTFLMSNITPQNPQINQRVWNKIEKRERQVALKLGSLEVL
NLVNYDNNPQRIKNNIAIPSSYTKILKGDNFKECYQVPNHDVENENLRIYKVKCDNF
>Mature_217_residues
MKKLIILSLLSTLAFADYTQYKPSEDFAKYFTKQNCSQVLDKFYYINCYDYSLKGTKAVAYRLEADNLKGEQIKKRPRFE
DDTNIPKKYRTTWSDYKNSGYDRGHTLSNASMRKTTQAQRSTFLMSNITPQNPQINQRVWNKIEKRERQVALKLGSLEVL
NLVNYDNNPQRIKNNIAIPSSYTKILKGDNFKECYQVPNHDVENENLRIYKVKCDNF

Specific function: Unknown

COG id: COG1864

COG function: function code F; DNA/RNA endonuclease G, NUC1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

Organism=Homo sapiens, GI53759134, Length=195, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17505967, Length=179, Percent_Identity=29.608938547486, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322253, Length=215, Percent_Identity=26.5116279069767, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24581065, Length=192, Percent_Identity=26.0416666666667, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604
- InterPro:   IPR020821 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: NA

Molecular weight: Translated: 25531; Mature: 25531

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLIILSLLSTLAFADYTQYKPSEDFAKYFTKQNCSQVLDKFYYINCYDYSLKGTKAVA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEE
YRLEADNLKGEQIKKRPRFEDDTNIPKKYRTTWSDYKNSGYDRGHTLSNASMRKTTQAQR
EEEECCCCCCHHHHHCCCCCCCCCCCHHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHH
STFLMSNITPQNPQINQRVWNKIEKRERQVALKLGSLEVLNLVNYDNNPQRIKNNIAIPS
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEHEECCCCCHHHHHCCCCCCC
SYTKILKGDNFKECYQVPNHDVENENLRIYKVKCDNF
HHHHHHCCCCHHHHHCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MKKLIILSLLSTLAFADYTQYKPSEDFAKYFTKQNCSQVLDKFYYINCYDYSLKGTKAVA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEE
YRLEADNLKGEQIKKRPRFEDDTNIPKKYRTTWSDYKNSGYDRGHTLSNASMRKTTQAQR
EEEECCCCCCHHHHHCCCCCCCCCCCHHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHH
STFLMSNITPQNPQINQRVWNKIEKRERQVALKLGSLEVLNLVNYDNNPQRIKNNIAIPS
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEHEECCCCCHHHHHCCCCCCC
SYTKILKGDNFKECYQVPNHDVENENLRIYKVKCDNF
HHHHHHCCCCHHHHHCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]