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The map label for this gene is ribD [H]

Identifier: 57238634

GI number: 57238634

Start: 1691440

End: 1692420

Strand: Direct

Name: ribD [H]

Synonym: CJE1794

Alternate gene names: 57238634

Gene position: 1691440-1692420 (Clockwise)

Preceding gene: 57238633

Following gene: 57238635

Centisome position: 95.14

GC content: 32.11

Gene sequence:

>981_bases
ATGAAAGAATTTTATATGAATTTAGCTTTAAATGAGGCTTGGAAATATCAGTTTTTAACCTATCCAAATCCAGCCGTAGG
CTGTGTAATCTTAGATAAAAATGAAAAAATTTTAGCCATAAAAGCTCATGAAAAAGCTGGATTGGCTCATGCAGAACTTA
ATGCCATAGCTCATGCTTTTAAAAGCTTAAGACCTGAAATTTCATTGCCTAAAGAAGTAAACGCCTTACATGAGTTTATT
TGCAAAAACCATCAAGGTGTATTTAAAGATAGTATAGCTTTTGTCACACTTGAGCCTTGCTCTCATCAAGGAAAAACGCC
TCCTTGCGCAAAACTCTTTAGCGAGCTAGGTTTTAAAAAAATTTTCATCAGCGTTAAAGATGAAAATAAAATCGCAAGTG
GTGGAGCTGAATTTTTAAAAAAACAAGGCATAGAAGTTGAATTTGACATACTTAAAGAAGAAGGGAAAAAACTTTTAAAA
CCTTTTTTAAAATGGCAAAAAGGGCAATTTAAACTTTTTAAATTAGCCCTTTCTATGAATGGCTCACCTTTTGGCAAAAT
CGTAAGCAATAAGCTAAGTCGCACTTATGCACATAAAATTAGAGCGGTGATTGATTTGCTTGTAGTCGGTGGAGAAACCA
TAAGAAAAGATCGCCCTATACTAGATGCTAGGCTTTGCAAAGCAAAAGCGCCTAATCTTTGTATCTTAAGCCGTCAAAAT
ATAGATAATTTTGATAAAAATATCCCTTTATTTAAAGTTCCAAACCGCCAAATTTATACCCAAATTCCAAGTGAGGCTAA
ATTTTTAATGTATGAGGGTGGAGAAAATTTTCTCAAAATCTTTAAAGATGAAATAGATATGTTTTTGATTTTCCAAAGTT
CAAGTTTAAATGATGAAAAAAATGTTACAATACCTTTAAATTTCAAGCCACTTTATAGGAATTTTTTAGGGAGTGATACT
TATGGCATTTATGAACTTTAG

Upstream 100 bases:

>100_bases
AAAAATAAGAAATACAAATGGAAAATTTAGAATTTATTATTTTAAAACAAAAATATAAAATTTTAAAAATATGTCAAATT
TTAAAATACAAGGTAGCTAA

Downstream 100 bases:

>100_bases
TGGATTTTTTTATGCGAGAAATGATTTAAGATTATTTAAAATAGAAAAGAAAAATGAATTAAAATCCTTTTTTTACAAAG
ACTACACCTTATCAAGCTAC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKEFYMNLALNEAWKYQFLTYPNPAVGCVILDKNEKILAIKAHEKAGLAHAELNAIAHAFKSLRPEISLPKEVNALHEFI
CKNHQGVFKDSIAFVTLEPCSHQGKTPPCAKLFSELGFKKIFISVKDENKIASGGAEFLKKQGIEVEFDILKEEGKKLLK
PFLKWQKGQFKLFKLALSMNGSPFGKIVSNKLSRTYAHKIRAVIDLLVVGGETIRKDRPILDARLCKAKAPNLCILSRQN
IDNFDKNIPLFKVPNRQIYTQIPSEAKFLMYEGGENFLKIFKDEIDMFLIFQSSSLNDEKNVTIPLNFKPLYRNFLGSDT
YGIYEL

Sequences:

>Translated_326_residues
MKEFYMNLALNEAWKYQFLTYPNPAVGCVILDKNEKILAIKAHEKAGLAHAELNAIAHAFKSLRPEISLPKEVNALHEFI
CKNHQGVFKDSIAFVTLEPCSHQGKTPPCAKLFSELGFKKIFISVKDENKIASGGAEFLKKQGIEVEFDILKEEGKKLLK
PFLKWQKGQFKLFKLALSMNGSPFGKIVSNKLSRTYAHKIRAVIDLLVVGGETIRKDRPILDARLCKAKAPNLCILSRQN
IDNFDKNIPLFKVPNRQIYTQIPSEAKFLMYEGGENFLKIFKDEIDMFLIFQSSSLNDEKNVTIPLNFKPLYRNFLGSDT
YGIYEL
>Mature_326_residues
MKEFYMNLALNEAWKYQFLTYPNPAVGCVILDKNEKILAIKAHEKAGLAHAELNAIAHAFKSLRPEISLPKEVNALHEFI
CKNHQGVFKDSIAFVTLEPCSHQGKTPPCAKLFSELGFKKIFISVKDENKIASGGAEFLKKQGIEVEFDILKEEGKKLLK
PFLKWQKGQFKLFKLALSMNGSPFGKIVSNKLSRTYAHKIRAVIDLLVVGGETIRKDRPILDARLCKAKAPNLCILSRQN
IDNFDKNIPLFKVPNRQIYTQIPSEAKFLMYEGGENFLKIFKDEIDMFLIFQSSSLNDEKNVTIPLNFKPLYRNFLGSDT
YGIYEL

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=282, Percent_Identity=28.3687943262411, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 37096; Mature: 37096

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEFYMNLALNEAWKYQFLTYPNPAVGCVILDKNEKILAIKAHEKAGLAHAELNAIAHAF
CCCEEEEEEECCCEEEEEEECCCCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHH
KSLRPEISLPKEVNALHEFICKNHQGVFKDSIAFVTLEPCSHQGKTPPCAKLFSELGFKK
HHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEE
IFISVKDENKIASGGAEFLKKQGIEVEFDILKEEGKKLLKPFLKWQKGQFKLFKLALSMN
EEEEEECCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
GSPFGKIVSNKLSRTYAHKIRAVIDLLVVGGETIRKDRPILDARLCKAKAPNLCILSRQN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHCCCCCEEEEECCC
IDNFDKNIPLFKVPNRQIYTQIPSEAKFLMYEGGENFLKIFKDEIDMFLIFQSSSLNDEK
CCCHHCCCCEEECCCCEEEEECCCCCEEEEEECCHHHHHHHHHCCCEEEEEECCCCCCCC
NVTIPLNFKPLYRNFLGSDTYGIYEL
CEEEEECCHHHHHHHCCCCCCEEEEC
>Mature Secondary Structure
MKEFYMNLALNEAWKYQFLTYPNPAVGCVILDKNEKILAIKAHEKAGLAHAELNAIAHAF
CCCEEEEEEECCCEEEEEEECCCCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHH
KSLRPEISLPKEVNALHEFICKNHQGVFKDSIAFVTLEPCSHQGKTPPCAKLFSELGFKK
HHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEE
IFISVKDENKIASGGAEFLKKQGIEVEFDILKEEGKKLLKPFLKWQKGQFKLFKLALSMN
EEEEEECCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
GSPFGKIVSNKLSRTYAHKIRAVIDLLVVGGETIRKDRPILDARLCKAKAPNLCILSRQN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHCCCCCEEEEECCC
IDNFDKNIPLFKVPNRQIYTQIPSEAKFLMYEGGENFLKIFKDEIDMFLIFQSSSLNDEK
CCCHHCCCCEEECCCCEEEEECCCCCEEEEEECCHHHHHHHHHCCCEEEEEECCCCCCCC
NVTIPLNFKPLYRNFLGSDTYGIYEL
CEEEEECCHHHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9297088 [H]