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The map label for this gene is htr2 [H]

Identifier: 57238529

GI number: 57238529

Start: 1579448

End: 1581550

Strand: Reverse

Name: htr2 [H]

Synonym: CJE1679

Alternate gene names: 57238529

Gene position: 1581550-1579448 (Counterclockwise)

Preceding gene: 57238530

Following gene: 57238528

Centisome position: 88.96

GC content: 30.34

Gene sequence:

>2103_bases
ATGTTTAAATCTTTAAATATAGGTTTAAAACTTATTTTTTCTGTGGCAGCTGTTGTTGTTATTGGACTTGTTATTTTAAT
TTCATTAATCACAAAACAAGTAAGTCAAAATATTACCAAAAATACAGAAGATATTCTTGCTTCTATCACGAAAGAATATG
CTACTCAAACTCAAGGAATTTTTGGGGAAATGATCGCTTTAAATAAAAGTATTTCAGGTACTTTAACAGAAATGTTTAGA
TCAACCTCTAAAGAAGATTTAGATATAGACAATATAACAAATATTATAACCAATACTTTTGATAATAGTGCTTATTCTAA
TTTTACTTATTTGTATCTTATTGATCCGCCAGAATACTTTAAAGAAGAGAGTAAATTTTTTAATACTCAAAGTGGAAAAT
TTGTTATGCTTTACGCTGATGAAGAAAAGGATAATAAAGGCGGAATAAAAGCAATACAAGCTAGTGATGAAATAGCTAAT
CTGCAAGTTGTGCAAGATATATTAAAAAAAGCAAAATATGGGGAAAATAAAGTATATATAGGCCGTCCTATTAAGATGAA
TTTAGAAGGTCAAGATTTTGATGCTGTAAATGTTGCTATGCCTATTTTTGATCGAAAAAATCAAGTTGTAGGTGTCATAG
GCATGACTTTAGATTTTTCAGATATTGCTACTTATCTTTTAGACCCTAAAGGTCAAAAATATGATGGTGAATTAAGAGTT
CTTTTAAATTCAGATGGTTTTATGGCGATACATCCAAATAAAAATCTAGTTTTAAAAAATTTAAAAGATATCAATCCTAA
TAAAGGTGCACAAGAAACTTATAAGGCCATAAGTGAAGGAAAAAATGGAGTTTTTAACTATATAGCTTCTGATGGTGATG
ATTCTTATGCTGCGATTAATAGTTTTAAAGTGCAAGATAGTTCTTGGGCAGTTTTGGTAACTGCTCCTAAATATTCAGTA
TTTAAACCCTTAAAAAAATTACAATTAATTATTCTTGGTGCATCTTTTATTTTTATTTTTGTTGTTTTAGGAGTGGTTTA
TTATTGCGTAAGAAAAATTGTCGCATCTAGATTGCCTGTGATTCTTAGTTCTTTAGAATCATTTTTCCGTTTTTTAAATC
ATGAAAAAATTGAACCTAAGGCTATTGAAATTCGTGCTAATGATGAGCTAGGAGCAATGGGAAGAATCATAAATGAAAAT
ATTGAAAAGATTCAAATATCTTTAGAACAAGATCAAAATGCTGTAGATGAATCGGTGCAAACTGCTAGAGAAATCGAAAA
GGGTAATTTAACTGCAAGAATTACTAAAAATCCTATAAATCCTCAATTAGTAGAACTTAAAAATGTTCTTAATAGGATGC
TTGATGTTTTACAAAGTAAAATTGGTTCTAATATGAATGAAATTAATAGAGTTTTTGATAGTTACAAGGCTCTTGATTTT
AGTACAGAAGTATTTAATGCTAAAGGTGAAGTTGAGATTACAACTAATATTTTAGGCAAAGAAATTAAAAAGATGCTTGT
AGCTTCTTCAAATTTTGCTAAAGATTTAGCCAATCAGTCAGAAGAGTTAAAAAATTCTATGCAAAAACTTGCTGATGGCT
CTAATGCACAAGCGAGTTCTTTAGAACAATCGGCTGCAGCTGTAGAGGAGATTAATTCTTCTATGCAAAATGTAAGTGGA
AAAACAGTTGAGGTTGCTTCACAAGCTGATGATATAAAAAATATTGTCAATGTGATTAAAGATATCGCTGAGCAAACGAA
TCTTCTTGCTTTAAATGCAGCTATTGAAGCTGCACGTGCTGGAGAACATGGGCGTGGTTTTGCAGTTGTTGCAGATGAGG
TAAGACAGCTTGCGGAAAGAACAGGAAAATCCTTATCTGAAATCGAGGCAAATATTAATATACTTGTTCAAAGCGTAAAT
GAAGTAGCAGAATCTGTAAAAGAACAAACAGCAGGAATCACACAGATTAACGATGCTATAGCACAACTTGAAACTGTAAC
TAAGGAAAATGTCGAAGTTGCAAATGTCACCAATAATATAACAAATGAAGTCAATCAAATTGCTGCGGCAATTCTTGAAG
ATGTGAATAAAAAAAGATTTTAA

Upstream 100 bases:

>100_bases
AAAATACTAATACATAATTTTTTTATAATTAATTAATATTATTTTTTTAAAAATATGTTAAAATTAGAATCTAAATTTTT
TATTTTTTAGGAGTTATAAG

Downstream 100 bases:

>100_bases
AAAAGCTCATTTTTGAGCTTTTAAATTTTTTCTATATTATTTAAAATTTTTAAACACAAAACAAGTAATAAAATAATATT
ATTTTTCAAAGCTAATATCA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: HTR-II; Methyl-accepting phototaxis protein II; MPP-II [H]

Number of amino acids: Translated: 700; Mature: 700

Protein sequence:

>700_residues
MFKSLNIGLKLIFSVAAVVVIGLVILISLITKQVSQNITKNTEDILASITKEYATQTQGIFGEMIALNKSISGTLTEMFR
STSKEDLDIDNITNIITNTFDNSAYSNFTYLYLIDPPEYFKEESKFFNTQSGKFVMLYADEEKDNKGGIKAIQASDEIAN
LQVVQDILKKAKYGENKVYIGRPIKMNLEGQDFDAVNVAMPIFDRKNQVVGVIGMTLDFSDIATYLLDPKGQKYDGELRV
LLNSDGFMAIHPNKNLVLKNLKDINPNKGAQETYKAISEGKNGVFNYIASDGDDSYAAINSFKVQDSSWAVLVTAPKYSV
FKPLKKLQLIILGASFIFIFVVLGVVYYCVRKIVASRLPVILSSLESFFRFLNHEKIEPKAIEIRANDELGAMGRIINEN
IEKIQISLEQDQNAVDESVQTAREIEKGNLTARITKNPINPQLVELKNVLNRMLDVLQSKIGSNMNEINRVFDSYKALDF
STEVFNAKGEVEITTNILGKEIKKMLVASSNFAKDLANQSEELKNSMQKLADGSNAQASSLEQSAAAVEEINSSMQNVSG
KTVEVASQADDIKNIVNVIKDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRQLAERTGKSLSEIEANINILVQSVN
EVAESVKEQTAGITQINDAIAQLETVTKENVEVANVTNNITNEVNQIAAAILEDVNKKRF

Sequences:

>Translated_700_residues
MFKSLNIGLKLIFSVAAVVVIGLVILISLITKQVSQNITKNTEDILASITKEYATQTQGIFGEMIALNKSISGTLTEMFR
STSKEDLDIDNITNIITNTFDNSAYSNFTYLYLIDPPEYFKEESKFFNTQSGKFVMLYADEEKDNKGGIKAIQASDEIAN
LQVVQDILKKAKYGENKVYIGRPIKMNLEGQDFDAVNVAMPIFDRKNQVVGVIGMTLDFSDIATYLLDPKGQKYDGELRV
LLNSDGFMAIHPNKNLVLKNLKDINPNKGAQETYKAISEGKNGVFNYIASDGDDSYAAINSFKVQDSSWAVLVTAPKYSV
FKPLKKLQLIILGASFIFIFVVLGVVYYCVRKIVASRLPVILSSLESFFRFLNHEKIEPKAIEIRANDELGAMGRIINEN
IEKIQISLEQDQNAVDESVQTAREIEKGNLTARITKNPINPQLVELKNVLNRMLDVLQSKIGSNMNEINRVFDSYKALDF
STEVFNAKGEVEITTNILGKEIKKMLVASSNFAKDLANQSEELKNSMQKLADGSNAQASSLEQSAAAVEEINSSMQNVSG
KTVEVASQADDIKNIVNVIKDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRQLAERTGKSLSEIEANINILVQSVN
EVAESVKEQTAGITQINDAIAQLETVTKENVEVANVTNNITNEVNQIAAAILEDVNKKRF
>Mature_700_residues
MFKSLNIGLKLIFSVAAVVVIGLVILISLITKQVSQNITKNTEDILASITKEYATQTQGIFGEMIALNKSISGTLTEMFR
STSKEDLDIDNITNIITNTFDNSAYSNFTYLYLIDPPEYFKEESKFFNTQSGKFVMLYADEEKDNKGGIKAIQASDEIAN
LQVVQDILKKAKYGENKVYIGRPIKMNLEGQDFDAVNVAMPIFDRKNQVVGVIGMTLDFSDIATYLLDPKGQKYDGELRV
LLNSDGFMAIHPNKNLVLKNLKDINPNKGAQETYKAISEGKNGVFNYIASDGDDSYAAINSFKVQDSSWAVLVTAPKYSV
FKPLKKLQLIILGASFIFIFVVLGVVYYCVRKIVASRLPVILSSLESFFRFLNHEKIEPKAIEIRANDELGAMGRIINEN
IEKIQISLEQDQNAVDESVQTAREIEKGNLTARITKNPINPQLVELKNVLNRMLDVLQSKIGSNMNEINRVFDSYKALDF
STEVFNAKGEVEITTNILGKEIKKMLVASSNFAKDLANQSEELKNSMQKLADGSNAQASSLEQSAAAVEEINSSMQNVSG
KTVEVASQADDIKNIVNVIKDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRQLAERTGKSLSEIEANINILVQSVN
EVAESVKEQTAGITQINDAIAQLETVTKENVEVANVTNNITNEVNQIAAAILEDVNKKRF

Specific function: Transduces signals from the phototaxis receptor sensory rhodopsin II (SR-II) to the flagellar motor. Responds to light changes through the variation of the level of methylation. Also acts as a chemotransducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=182, Percent_Identity=37.9120879120879, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788194, Length=275, Percent_Identity=32, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI2367378, Length=268, Percent_Identity=30.2238805970149, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1787690, Length=244, Percent_Identity=30.7377049180328, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1789453, Length=260, Percent_Identity=28.8461538461538, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 77272; Mature: 77272

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKSLNIGLKLIFSVAAVVVIGLVILISLITKQVSQNITKNTEDILASITKEYATQTQGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FGEMIALNKSISGTLTEMFRSTSKEDLDIDNITNIITNTFDNSAYSNFTYLYLIDPPEYF
HHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHH
KEESKFFNTQSGKFVMLYADEEKDNKGGIKAIQASDEIANLQVVQDILKKAKYGENKVYI
HHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEE
GRPIKMNLEGQDFDAVNVAMPIFDRKNQVVGVIGMTLDFSDIATYLLDPKGQKYDGELRV
CCCEEECCCCCCCCCCEEEECCCCCCCCEEEEEEEEEEHHHHHHHHCCCCCCCCCCCEEE
LLNSDGFMAIHPNKNLVLKNLKDINPNKGAQETYKAISEGKNGVFNYIASDGDDSYAAIN
EECCCCEEEECCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCEEHHHCCCCCCCCHHHE
SFKVQDSSWAVLVTAPKYSVFKPLKKLQLIILGASFIFIFVVLGVVYYCVRKIVASRLPV
EEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSSLESFFRFLNHEKIEPKAIEIRANDELGAMGRIINENIEKIQISLEQDQNAVDESVQ
HHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCHHHEEEEHHHCCHHHHHHHH
TAREIEKGNLTARITKNPINPQLVELKNVLNRMLDVLQSKIGSNMNEINRVFDSYKALDF
HHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
STEVFNAKGEVEITTNILGKEIKKMLVASSNFAKDLANQSEELKNSMQKLADGSNAQASS
CHHHHCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LEQSAAAVEEINSSMQNVSGKTVEVASQADDIKNIVNVIKDIAEQTNLLALNAAIEAARA
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHC
GEHGRGFAVVADEVRQLAERTGKSLSEIEANINILVQSVNEVAESVKEQTAGITQINDAI
CCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AQLETVTKENVEVANVTNNITNEVNQIAAAILEDVNKKRF
HHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKSLNIGLKLIFSVAAVVVIGLVILISLITKQVSQNITKNTEDILASITKEYATQTQGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FGEMIALNKSISGTLTEMFRSTSKEDLDIDNITNIITNTFDNSAYSNFTYLYLIDPPEYF
HHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHH
KEESKFFNTQSGKFVMLYADEEKDNKGGIKAIQASDEIANLQVVQDILKKAKYGENKVYI
HHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEE
GRPIKMNLEGQDFDAVNVAMPIFDRKNQVVGVIGMTLDFSDIATYLLDPKGQKYDGELRV
CCCEEECCCCCCCCCCEEEECCCCCCCCEEEEEEEEEEHHHHHHHHCCCCCCCCCCCEEE
LLNSDGFMAIHPNKNLVLKNLKDINPNKGAQETYKAISEGKNGVFNYIASDGDDSYAAIN
EECCCCEEEECCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCEEHHHCCCCCCCCHHHE
SFKVQDSSWAVLVTAPKYSVFKPLKKLQLIILGASFIFIFVVLGVVYYCVRKIVASRLPV
EEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSSLESFFRFLNHEKIEPKAIEIRANDELGAMGRIINENIEKIQISLEQDQNAVDESVQ
HHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCHHHEEEEHHHCCHHHHHHHH
TAREIEKGNLTARITKNPINPQLVELKNVLNRMLDVLQSKIGSNMNEINRVFDSYKALDF
HHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
STEVFNAKGEVEITTNILGKEIKKMLVASSNFAKDLANQSEELKNSMQKLADGSNAQASS
CHHHHCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LEQSAAAVEEINSSMQNVSGKTVEVASQADDIKNIVNVIKDIAEQTNLLALNAAIEAARA
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHC
GEHGRGFAVVADEVRQLAERTGKSLSEIEANINILVQSVNEVAESVKEQTAGITQINDAI
CCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AQLETVTKENVEVANVTNNITNEVNQIAAAILEDVNKKRF
HHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8710852; 11016950 [H]