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The map label for this gene is kpsT [H]

Identifier: 57238470

GI number: 57238470

Start: 1524836

End: 1525498

Strand: Reverse

Name: kpsT [H]

Synonym: CJE1620

Alternate gene names: 57238470

Gene position: 1525498-1524836 (Counterclockwise)

Preceding gene: 57238471

Following gene: 57238469

Centisome position: 85.81

GC content: 33.63

Gene sequence:

>663_bases
ATGATAAAGCTAATTAATCTAACTAAATCTTATCCTTTATTTAGTGGCGGAAGGCATTATGTTTTTAAAAATTTTACTTT
TGAATTTCCTGAAAATTGTAGTATAGGATTGATGGGGGGTAATGGCGCAGGCAAGTCCACTCTCATGAGACTCTTAAGTG
GAGCAGAGCTTCCTGATAATGGTAAGATAATTACTAATAAAAAATTATCTTGGCCTTTGGGTTTAAATGGGGCTTTTCAA
GGTTCTTTAACCGCTAGAGATAATGCTAAATTTGTAGCTAGAGTGTATGGTTATAAAGGCAAGGAACTTCAAGAAAAAGT
AAAATTCGTAGAAGATTTTGCAGAGCTTGGGAAATTTTTTGATGAGCCTATGAAGACTTATTCTTCGGGAATGAGTGCTA
GGATAGCTTTTGGACTTAGCATGGCTTTTGATTTTGATTATTATTTGATCGATGAAGCGGGAGCTGTTGGAGATCCTGCT
TTTAGGGAAAAAAGCGTGAAATTATATAGAGAAAGATTAAGCAAATCAAAAGTGATTATGGTATCTCATAATGTAGCTGA
AATTAAAGAATGGTGTGATAAAATAATTTATATGAAAAATGGACAAATTACGGTTTATGATGATGTAGATGAAGGAATAG
CTGTGTATCAAGGAAAGGCTTAA

Upstream 100 bases:

>100_bases
ATAGTTATTTTTATGCTATATTTTGGATTTTACTAGTTTTATTTATAGGGCTTTTTATTTACTACTATAATAGACAAGCT
CTAACGGCGGCAAAAAAAGA

Downstream 100 bases:

>100_bases
TGGAAGAAAATAAAACTTTACTGGAAAAAATCAAAGATTTAAGTATATTTGATTCTTTTAAAATTGTTTGGTTTATAATG
ATTCTTGTTGTGATTTATTA

Product: capsular polysaccharide ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MIKLINLTKSYPLFSGGRHYVFKNFTFEFPENCSIGLMGGNGAGKSTLMRLLSGAELPDNGKIITNKKLSWPLGLNGAFQ
GSLTARDNAKFVARVYGYKGKELQEKVKFVEDFAELGKFFDEPMKTYSSGMSARIAFGLSMAFDFDYYLIDEAGAVGDPA
FREKSVKLYRERLSKSKVIMVSHNVAEIKEWCDKIIYMKNGQITVYDDVDEGIAVYQGKA

Sequences:

>Translated_220_residues
MIKLINLTKSYPLFSGGRHYVFKNFTFEFPENCSIGLMGGNGAGKSTLMRLLSGAELPDNGKIITNKKLSWPLGLNGAFQ
GSLTARDNAKFVARVYGYKGKELQEKVKFVEDFAELGKFFDEPMKTYSSGMSARIAFGLSMAFDFDYYLIDEAGAVGDPA
FREKSVKLYRERLSKSKVIMVSHNVAEIKEWCDKIIYMKNGQITVYDDVDEGIAVYQGKA
>Mature_220_residues
MIKLINLTKSYPLFSGGRHYVFKNFTFEFPENCSIGLMGGNGAGKSTLMRLLSGAELPDNGKIITNKKLSWPLGLNGAFQ
GSLTARDNAKFVARVYGYKGKELQEKVKFVEDFAELGKFFDEPMKTYSSGMSARIAFGLSMAFDFDYYLIDEAGAVGDPA
FREKSVKLYRERLSKSKVIMVSHNVAEIKEWCDKIIYMKNGQITVYDDVDEGIAVYQGKA

Specific function: Putative ATP-binding protein, and an energy coupling component for the transport of polysialic acid across the cytoplasmic membrane [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27881501, Length=216, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI30795238, Length=216, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI45446740, Length=216, Percent_Identity=25.9259259259259, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI47078218, Length=216, Percent_Identity=25.9259259259259, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI27477115, Length=190, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=7e-14,
Organism=Homo sapiens, GI27436953, Length=215, Percent_Identity=26.046511627907, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI6005701, Length=191, Percent_Identity=25.6544502617801, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI153792144, Length=215, Percent_Identity=25.5813953488372, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI48994943, Length=213, Percent_Identity=24.4131455399061, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1790467, Length=215, Percent_Identity=26.046511627907, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1786398, Length=230, Percent_Identity=25.2173913043478, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081782, Length=222, Percent_Identity=25.2252252252252, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789032, Length=226, Percent_Identity=24.7787610619469, Blast_Score=62, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007184, Length=190, Percent_Identity=26.8421052631579, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI221500365, Length=190, Percent_Identity=26.8421052631579, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24666092, Length=201, Percent_Identity=27.363184079602, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24582014, Length=186, Percent_Identity=27.4193548387097, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582012, Length=186, Percent_Identity=27.4193548387097, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24621; Mature: 24621

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLINLTKSYPLFSGGRHYVFKNFTFEFPENCSIGLMGGNGAGKSTLMRLLSGAELPDN
CEEEEECCCCCCCCCCCCEEEEECEEEECCCCCEEEEEECCCCCHHHHHHHHHCCCCCCC
GKIITNKKLSWPLGLNGAFQGSLTARDNAKFVARVYGYKGKELQEKVKFVEDFAELGKFF
CEEEECCCCCCCCCCCCCCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
DEPMKTYSSGMSARIAFGLSMAFDFDYYLIDEAGAVGDPAFREKSVKLYRERLSKSKVIM
HHHHHHHHCCCCEEEEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEE
VSHNVAEIKEWCDKIIYMKNGQITVYDDVDEGIAVYQGKA
EECCHHHHHHHHHHEEEEECCCEEEEECCCCCEEEEECCC
>Mature Secondary Structure
MIKLINLTKSYPLFSGGRHYVFKNFTFEFPENCSIGLMGGNGAGKSTLMRLLSGAELPDN
CEEEEECCCCCCCCCCCCEEEEECEEEECCCCCEEEEEECCCCCHHHHHHHHHCCCCCCC
GKIITNKKLSWPLGLNGAFQGSLTARDNAKFVARVYGYKGKELQEKVKFVEDFAELGKFF
CEEEECCCCCCCCCCCCCCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
DEPMKTYSSGMSARIAFGLSMAFDFDYYLIDEAGAVGDPAFREKSVKLYRERLSKSKVIM
HHHHHHHHCCCCEEEEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEE
VSHNVAEIKEWCDKIIYMKNGQITVYDDVDEGIAVYQGKA
EECCHHHHHHHHHHEEEEECCCEEEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2082146 [H]