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The map label for this gene is ptmC

Identifier: 57238373

GI number: 57238373

Start: 1406883

End: 1407887

Strand: Direct

Name: ptmC

Synonym: CJE1516

Alternate gene names: NA

Gene position: 1406883-1407887 (Clockwise)

Preceding gene: 57238372

Following gene: 57238374

Centisome position: 79.13

GC content: 34.53

Gene sequence:

>1005_bases
ATGAAAAAAACTCTTATCATCGCAGAAGCAGGAGTCAATCACAATGGTGATTTAAATTTAGCTAAAAAGTTAATAGAAAT
CGCAGCAGATTCAGGGGCTGATTTTGTTAAATTTCAAAGTTTTAAAGCCAAAAACTGTATCAGCACAAAGGCTAAAAAAG
CGCCCTATCAGCTTAAAACCACAGCTAGTGATGAGAGTCAGCTTCAAATGGTACAAAAACTCGAACTCGATCTTAAAGCT
CATAAAGAGCTTATCTTACACGCAAAAAAATGCAATATTGCCTTTCTTTCTACTCCTTTTGATCTTGAAAGTGTAGATCT
TTTAAATGAGTTAGGCTTAAAAATCTTTAAAATTCCAAGCGGAGAAATCACCAATCTACCCTATCTTAAAAAAATTGCAA
AGCTTAATAAAAAAATCATACTTTCAACAGGTATGGCAAATTTAGGCGAGGTAGAAGAAGCTTTAAATGTGCTTTGTAAA
AATGGCGCTAAACGCCAAAATATCACTCTTTTACACTGTACTACAGAATACCCTGCCCCTTTTGATGAAGTCAATCTTAA
AGCCATGCAAAGCTTAAAAGACGCTTTTAAGCTTGATGTGGGTTATTCTGATCACACTCAAGGCATACACATTTCTCTAG
CTGCAGTTGCCTTGGGAGCTTGTGTAATAGAAAAGCATTTTACTCTAGACAAAAATATGTCAGGGCCTGATCATAAAGCA
AGTTTAGAACCTCAAGAACTAAAAATGCTTTGCACCCAAATAAGACAAATACAAAAGGCAATGGGTGATGGCATAAAAAA
AGCAAGTAAAAGCGAACAAAAAAATATCAACATAGTAAGAAAAAGTTTAGTCGCTAAAAAAGATATCCAAAAAGGAGAAA
TTTTTAGCGAAGAAAATCTTACTACCAAACGCCCCGCAAATGGTATAAGTGCTATGAGATATGAAGAGTTTTTAGGTAAA
ATTGCTACTAAAAACTACAAAGAAGATGAGCTTATCCGTGAGTAA

Upstream 100 bases:

>100_bases
ATGATATTTTTTGAATAAAACCTATAATTTGTATATCAAACATATAGTAATATTGGAATATTTTTTGCTTTATATACTAA
AAATTATAAGGATAAAAATT

Downstream 100 bases:

>100_bases
AAGAAAAATTTGTATAGTCAGTGCAACAAGGGCTGAATGGTATCTTTTAAGAAATTTATGTCATGAAATTCAAAACGATA
AAGATCTAAGCCTTCAAATC

Product: N-acetylneuraminic acid synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKKTLIIAEAGVNHNGDLNLAKKLIEIAADSGADFVKFQSFKAKNCISTKAKKAPYQLKTTASDESQLQMVQKLELDLKA
HKELILHAKKCNIAFLSTPFDLESVDLLNELGLKIFKIPSGEITNLPYLKKIAKLNKKIILSTGMANLGEVEEALNVLCK
NGAKRQNITLLHCTTEYPAPFDEVNLKAMQSLKDAFKLDVGYSDHTQGIHISLAAVALGACVIEKHFTLDKNMSGPDHKA
SLEPQELKMLCTQIRQIQKAMGDGIKKASKSEQKNINIVRKSLVAKKDIQKGEIFSEENLTTKRPANGISAMRYEEFLGK
IATKNYKEDELIRE

Sequences:

>Translated_334_residues
MKKTLIIAEAGVNHNGDLNLAKKLIEIAADSGADFVKFQSFKAKNCISTKAKKAPYQLKTTASDESQLQMVQKLELDLKA
HKELILHAKKCNIAFLSTPFDLESVDLLNELGLKIFKIPSGEITNLPYLKKIAKLNKKIILSTGMANLGEVEEALNVLCK
NGAKRQNITLLHCTTEYPAPFDEVNLKAMQSLKDAFKLDVGYSDHTQGIHISLAAVALGACVIEKHFTLDKNMSGPDHKA
SLEPQELKMLCTQIRQIQKAMGDGIKKASKSEQKNINIVRKSLVAKKDIQKGEIFSEENLTTKRPANGISAMRYEEFLGK
IATKNYKEDELIRE
>Mature_334_residues
MKKTLIIAEAGVNHNGDLNLAKKLIEIAADSGADFVKFQSFKAKNCISTKAKKAPYQLKTTASDESQLQMVQKLELDLKA
HKELILHAKKCNIAFLSTPFDLESVDLLNELGLKIFKIPSGEITNLPYLKKIAKLNKKIILSTGMANLGEVEEALNVLCK
NGAKRQNITLLHCTTEYPAPFDEVNLKAMQSLKDAFKLDVGYSDHTQGIHISLAAVALGACVIEKHFTLDKNMSGPDHKA
SLEPQELKMLCTQIRQIQKAMGDGIKKASKSEQKNINIVRKSLVAKKDIQKGEIFSEENLTTKRPANGISAMRYEEFLGK
IATKNYKEDELIRE

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=332, Percent_Identity=35.2409638554217, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI21357081, Length=352, Percent_Identity=33.2386363636364, Blast_Score=164, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 37096; Mature: 37096

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLIIAEAGVNHNGDLNLAKKLIEIAADSGADFVKFQSFKAKNCISTKAKKAPYQLKT
CCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHECCCCHHHHHHHHHHCCCEEEEE
TASDESQLQMVQKLELDLKAHKELILHAKKCNIAFLSTPFDLESVDLLNELGLKIFKIPS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEECCC
GEITNLPYLKKIAKLNKKIILSTGMANLGEVEEALNVLCKNGAKRQNITLLHCTTEYPAP
CCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCC
FDEVNLKAMQSLKDAFKLDVGYSDHTQGIHISLAAVALGACVIEKHFTLDKNMSGPDHKA
HHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SLEPQELKMLCTQIRQIQKAMGDGIKKASKSEQKNINIVRKSLVAKKDIQKGEIFSEENL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TTKRPANGISAMRYEEFLGKIATKNYKEDELIRE
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCC
>Mature Secondary Structure
MKKTLIIAEAGVNHNGDLNLAKKLIEIAADSGADFVKFQSFKAKNCISTKAKKAPYQLKT
CCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHECCCCHHHHHHHHHHCCCEEEEE
TASDESQLQMVQKLELDLKAHKELILHAKKCNIAFLSTPFDLESVDLLNELGLKIFKIPS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEECCC
GEITNLPYLKKIAKLNKKIILSTGMANLGEVEEALNVLCKNGAKRQNITLLHCTTEYPAP
CCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCC
FDEVNLKAMQSLKDAFKLDVGYSDHTQGIHISLAAVALGACVIEKHFTLDKNMSGPDHKA
HHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SLEPQELKMLCTQIRQIQKAMGDGIKKASKSEQKNINIVRKSLVAKKDIQKGEIFSEENL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TTKRPANGISAMRYEEFLGKIATKNYKEDELIRE
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]