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The map label for this gene is purQ [H]

Identifier: 57238283

GI number: 57238283

Start: 558490

End: 559137

Strand: Direct

Name: purQ [H]

Synonym: CJE0621

Alternate gene names: 57238283

Gene position: 558490-559137 (Clockwise)

Preceding gene: 57238284

Following gene: 57238282

Centisome position: 31.41

GC content: 31.79

Gene sequence:

>648_bases
ATGAAAGTTGCTATTATTAGATTTCTAGGGACAAATTGTGAATTTGATACAGCTTATGCCTTTGAAAAACTTGGAGTAAA
AACGCAGATTATTTGGCATGAAGAAAAAGAATTTGATGCAGATTTAGTTGTTTTGCCAGGCGGATTTTCTTATGGAGATT
ATCTAAGATGTGCAGCTATTGCAAAACTTGCTCCTGCTATGCAAGGTGTTTTTAATCATGCAAAAAAGGGAGGATATATC
TTAGGTATTTGTAATGGTTTTCAAATTTTACTTGAAAGCGGTCTTTTAAAAGGTGCAATGAAGCATAACAACAATCTTAG
TTTTATCTCAAAAAACCAAAATTTAAGAGTAGTTTCTAATGGTAATGCCTTTTTGAAAAATTTCAAAAAAGATGAAATTA
TTAATTTACCAATTGCCCATGGAGAGGGAAATTATTACGCTGATGAGGCTACTTTAAAAGAATTGCAAGATAAAGATCTT
ATTACTTTAAAATACGAGCCAAATCCAAATGGTTCTGTATTTGATATCGCAGGAATTTGTGATGAAAACAAAAAAATCTT
TGGACTCATGCCACATCCTGAGCGTGCTTGTGAAAAAGTCCTAGGTAATGATATAGGTTTGAAAATGCTTAAAGGCTTTT
TATTTTGA

Upstream 100 bases:

>100_bases
GATGAAAAATTAGCCAAAGAACAAGTAAAAAAAATGTGTGAAGAGTTGTTGGTAAATAGCGTCATTGAAGATTATGAGCT
TATAATTGAGAAAGAGTAAA

Downstream 100 bases:

>100_bases
AAATTTTATTAACTTTAATTTTTAGTGTTGTTGTATTGTTTGGCAGGGGTGAAATTTCTGTATTTAGCGGCCAAGATGAA
AATATGCAAAAAGAATTACA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKVAIIRFLGTNCEFDTAYAFEKLGVKTQIIWHEEKEFDADLVVLPGGFSYGDYLRCAAIAKLAPAMQGVFNHAKKGGYI
LGICNGFQILLESGLLKGAMKHNNNLSFISKNQNLRVVSNGNAFLKNFKKDEIINLPIAHGEGNYYADEATLKELQDKDL
ITLKYEPNPNGSVFDIAGICDENKKIFGLMPHPERACEKVLGNDIGLKMLKGFLF

Sequences:

>Translated_215_residues
MKVAIIRFLGTNCEFDTAYAFEKLGVKTQIIWHEEKEFDADLVVLPGGFSYGDYLRCAAIAKLAPAMQGVFNHAKKGGYI
LGICNGFQILLESGLLKGAMKHNNNLSFISKNQNLRVVSNGNAFLKNFKKDEIINLPIAHGEGNYYADEATLKELQDKDL
ITLKYEPNPNGSVFDIAGICDENKKIFGLMPHPERACEKVLGNDIGLKMLKGFLF
>Mature_215_residues
MKVAIIRFLGTNCEFDTAYAFEKLGVKTQIIWHEEKEFDADLVVLPGGFSYGDYLRCAAIAKLAPAMQGVFNHAKKGGYI
LGICNGFQILLESGLLKGAMKHNNNLSFISKNQNLRVVSNGNAFLKNFKKDEIINLPIAHGEGNYYADEATLKELQDKDL
ITLKYEPNPNGSVFDIAGICDENKKIFGLMPHPERACEKVLGNDIGLKMLKGFLF

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=235, Percent_Identity=27.6595744680851, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321498, Length=234, Percent_Identity=29.9145299145299, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582111, Length=184, Percent_Identity=31.5217391304348, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24582109, Length=184, Percent_Identity=31.5217391304348, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17137292, Length=184, Percent_Identity=31.5217391304348, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23881; Mature: 23881

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAIIRFLGTNCEFDTAYAFEKLGVKTQIIWHEEKEFDADLVVLPGGFSYGDYLRCAAI
CEEEEEEEECCCCCCCHHHHHHHCCCEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHH
AKLAPAMQGVFNHAKKGGYILGICNGFQILLESGLLKGAMKHNNNLSFISKNQNLRVVSN
HHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEC
GNAFLKNFKKDEIINLPIAHGEGNYYADEATLKELQDKDLITLKYEPNPNGSVFDIAGIC
CCHHHHCCCCCCEEEEEEEECCCCEEECHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEE
DENKKIFGLMPHPERACEKVLGNDIGLKMLKGFLF
CCCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure
MKVAIIRFLGTNCEFDTAYAFEKLGVKTQIIWHEEKEFDADLVVLPGGFSYGDYLRCAAI
CEEEEEEEECCCCCCCHHHHHHHCCCEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHH
AKLAPAMQGVFNHAKKGGYILGICNGFQILLESGLLKGAMKHNNNLSFISKNQNLRVVSN
HHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEC
GNAFLKNFKKDEIINLPIAHGEGNYYADEATLKELQDKDLITLKYEPNPNGSVFDIAGIC
CCHHHHCCCCCCEEEEEEEECCCCEEECHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEE
DENKKIFGLMPHPERACEKVLGNDIGLKMLKGFLF
CCCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]