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The map label for this gene is plsC [H]

Identifier: 57238281

GI number: 57238281

Start: 560311

End: 561003

Strand: Direct

Name: plsC [H]

Synonym: CJE0623

Alternate gene names: 57238281

Gene position: 560311-561003 (Clockwise)

Preceding gene: 57238282

Following gene: 57238280

Centisome position: 31.52

GC content: 28.86

Gene sequence:

>693_bases
ATGATTTACAAAAAAATTAAAGCTCTTTATTTTTGGATTTTTTTTGTTTTAAGTGTTGCTTTGGTGATTTTTTGTTTTTG
CTTTACAAAATCTCAAAACACACTTTGGAAAATCCGCAAAATTTGGGCTAAATTTCAAAGATATACTATCTCTTATAAAC
AAGAAATTATTGGCACTTTTAATCCGCAAGCTCAGATGATTTTAATGAATCATCAAAGTGCTTTAGATATCATCGCTTTA
GAAGAATTATATCCTAAAAATTTATGCTGGATTGCCAAAAAAGAATTAGGAGAAATTCCTATTTTCAAAGTTGCTATGAA
AAAACCAAAACTTCTTTGTATAGATAGAAAAAATCCGCGTGATTTGGTACGAGTTTTAAAAGAAGCAAAAGAAAGAATTA
GCGAAGATAGGGTTTTGGCTATTTTTCCAGAAGGAACTAGATCTAAAAATGAAAAAATGCTTAAATTTCAAAGTGGAGCA
AAAATTTTAAGTGAAAAATTAAATCTTAAAGTTCAACCCATTTTAATTGTGGATTCTGCAAAAATTTTAGACACAAAAAG
TTTTAGTGCAAGCAGCGGAGTGCTTAAAATCATTTGTATGGATTTAGTCGATACAAATGATGACAAATGGCTTGAAAACA
CTAGAAAAAAAATGCAAGAATTACTCGATCAAGAAAGAGCTAAGCTTTGCTAA

Upstream 100 bases:

>100_bases
TATACGGCAAATGCAGATGAAAAAGTAGAAGTTTTGGGCAAAAGACAAAATTATATTAAAGTATTGTTTTCTGATGGAAA
AATAGGTTGGGTTAATAAAG

Downstream 100 bases:

>100_bases
ATACCCTTTTAGTTGTTGGTTTTGGGGGATTTATAGGAGCAATCTTAAGAATGTTTTCTATTAATTTAGTGAATAAATTT
TTTCCTTATTCTATCAGCCT

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MIYKKIKALYFWIFFVLSVALVIFCFCFTKSQNTLWKIRKIWAKFQRYTISYKQEIIGTFNPQAQMILMNHQSALDIIAL
EELYPKNLCWIAKKELGEIPIFKVAMKKPKLLCIDRKNPRDLVRVLKEAKERISEDRVLAIFPEGTRSKNEKMLKFQSGA
KILSEKLNLKVQPILIVDSAKILDTKSFSASSGVLKIICMDLVDTNDDKWLENTRKKMQELLDQERAKLC

Sequences:

>Translated_230_residues
MIYKKIKALYFWIFFVLSVALVIFCFCFTKSQNTLWKIRKIWAKFQRYTISYKQEIIGTFNPQAQMILMNHQSALDIIAL
EELYPKNLCWIAKKELGEIPIFKVAMKKPKLLCIDRKNPRDLVRVLKEAKERISEDRVLAIFPEGTRSKNEKMLKFQSGA
KILSEKLNLKVQPILIVDSAKILDTKSFSASSGVLKIICMDLVDTNDDKWLENTRKKMQELLDQERAKLC
>Mature_230_residues
MIYKKIKALYFWIFFVLSVALVIFCFCFTKSQNTLWKIRKIWAKFQRYTISYKQEIIGTFNPQAQMILMNHQSALDIIAL
EELYPKNLCWIAKKELGEIPIFKVAMKKPKLLCIDRKNPRDLVRVLKEAKERISEDRVLAIFPEGTRSKNEKMLKFQSGA
KILSEKLNLKVQPILIVDSAKILDTKSFSASSGVLKIICMDLVDTNDDKWLENTRKKMQELLDQERAKLC

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=201, Percent_Identity=28.3582089552239, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI15100175, Length=201, Percent_Identity=28.3582089552239, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI6041665, Length=143, Percent_Identity=27.972027972028, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564032, Length=139, Percent_Identity=28.7769784172662, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320151, Length=209, Percent_Identity=23.444976076555, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281364648, Length=166, Percent_Identity=30.1204819277108, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582856, Length=166, Percent_Identity=30.1204819277108, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582854, Length=166, Percent_Identity=30.1204819277108, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 26885; Mature: 26885

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS00989 CLAT_ADAPTOR_S

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYKKIKALYFWIFFVLSVALVIFCFCFTKSQNTLWKIRKIWAKFQRYTISYKQEIIGTF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPQAQMILMNHQSALDIIALEELYPKNLCWIAKKELGEIPIFKVAMKKPKLLCIDRKNPR
CCCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCEEEEECCCHH
DLVRVLKEAKERISEDRVLAIFPEGTRSKNEKMLKFQSGAKILSEKLNLKVQPILIVDSA
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCC
KILDTKSFSASSGVLKIICMDLVDTNDDKWLENTRKKMQELLDQERAKLC
HHEECCCCCCCCCHHHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIYKKIKALYFWIFFVLSVALVIFCFCFTKSQNTLWKIRKIWAKFQRYTISYKQEIIGTF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPQAQMILMNHQSALDIIALEELYPKNLCWIAKKELGEIPIFKVAMKKPKLLCIDRKNPR
CCCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCEEEEECCCHH
DLVRVLKEAKERISEDRVLAIFPEGTRSKNEKMLKFQSGAKILSEKLNLKVQPILIVDSA
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCC
KILDTKSFSASSGVLKIICMDLVDTNDDKWLENTRKKMQELLDQERAKLC
HHEECCCCCCCCCHHHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]