Click here to switch to the map view.

The map label for this gene is htpG [H]

Identifier: 57238279

GI number: 57238279

Start: 561438

End: 563264

Strand: Direct

Name: htpG [H]

Synonym: CJE0625

Alternate gene names: 57238279

Gene position: 561438-563264 (Clockwise)

Preceding gene: 57238280

Following gene: 57238278

Centisome position: 31.58

GC content: 29.45

Gene sequence:

>1827_bases
ATGCAATTTCAAACCGAAGTCAATCAGCTTTTACAGCTTATGATACATTCTTTATATTCTAATAAAGAAATTTTTTTAAG
AGAACTTATTTCAAATGCAAGCGATGCTTTAGATAAGCTTAATTTTTTAAGCGTAAGTGATGATAAATATAAAAGCTTAA
AATTTGAACCTAAAATTGAAATCAAAATTGATAAAGATAAAAAAACTTTAAGTATTAGTGATAATGGTATAGGTATGGAT
AAAGATGATCTTATCAACAACCTTGGAACCATAGCAAAAAGTGGCACTAAAAGCTTTTTAGAAAATTTGAGCGGTGATGC
TAAAAAAGATTCTCAACTCATAGGACAATTTGGAGTAGGTTTTTATTCTGCTTTTATGGTGGCTAGCAAAATCGAAGTTT
TAAGTAAAAAAGCTTTAGATGATAAAGCTTATCTTTGGAGTTCCGATGCAAATGGTTATGAGATTAATGACGCAAGCAAA
GAAGAACAAGGAACAAGCATTACTTTATATTTAAAAGATGATGAGTTTGCTAATACTTATAAAATCGAAAGCATTATAGA
AAAATATTCTAATCATATTCAATTTCCAATTTTCATGGAAAAAGAAGAATTTACTCCTGCTAAAGAGGGCGAAGAAGAAG
GAAAAACTGAACTTAAAATTTCTCAAATCAATAAAGCCAATGCTTTATGGAGAATGCAAAAATCAAGCCTTAAAGCAGAA
GATTATGAAAGATTTTATGAGCAAAATTTTCATGATTCAAACAAACCTTTACTTTATCTTCACACTAAAAGCGAAGGAAA
ATTAGAATACAATTCCTTATTTTTCATACCACAAAATGCACCTTTTGATTTATTTCGTGTGGATTATCAAAGCGGCTTAA
AACTTTATGTAAAACGCGTATTTATCAGCGATGATGATAAAGAACTTTTACCAACTTATTTGCGTTTTGTGCGAGGGATT
ATCGATGTAGAAGATTTACCACTTAATGTAAGTCGTGAAATTTTACAAGAAAATCAAATTTTAAAAGGTGTCAAAGAAGC
TAGCGTTAAAAAGATTTTAGGTGAACTTGAAAAACTCAAAAACAATGATAAAGAAAAATACTTATCTTTCTTTAAAACCT
TTGGTAAAGTATTAAAAGAAGGACTTTATGGTTTTGGCGGAGAAAAAGATAGTCTTTTAAAACTCATGCTTTATAAAAGC
ACTAAAGGTGAAAATTTACGCTCTTTAGAGGAGTATAAAAACGACCTTCAAGGCGAACAAAAGGAAATTTTTTATATAGC
AGGAAATAATGAAAGTTTATTAAGAACCTCCCCTTTACTTGAAGAGTATAAACAAAAAAATATAGAAGTTTTACTCATGG
ATGATGAGATTGATTCTTTGGTAACTCCTATGCTAGAATTTGAAGGTTTGAAATTTATAGCTATTAATCAAGTAGAAGAT
AAAAATGAACTAAGCGATGAAGAAAAAAATACTTTTGCTCCACTTGTAGCTAAATTTAAAGAACTTCTAAAAGATCAAGT
TGAAGATGTAAGACTAACCAGTCGTTTAAAAGATAGCCCAAGTTGTATAGTTTATGATAAAAATAAACCTGATTTTGCTA
TGCAACAACTCTTAAAACAAATGGGTCAAGAACAAAATTTCAAACCTATTTTAGAAATCAATCCAAAACATGCTATTTTT
ACAGGTCTTAAAAACAACGAAAGCTTTAGTGCGGATATAGCAACCCTAGTTTTAAATATGGCAAAACTAAGCGAAGGTAT
GGGAGTGGATAATCCTGCTGAATTTAATGCAAGCCTTACAAAAATTATCAATAAGGCTTTTTCATGA

Upstream 100 bases:

>100_bases
ATGGCTTGGTTTTATAATTTTCAAATAAATCTTTAAATTTACTTTAGAATTTGTATTTTTTGCTAAAATACCACTTTAAA
AAATTACAAAGGAAGTTAAA

Downstream 100 bases:

>100_bases
TAGAAAATATCCCTGCAAGTCTTTGGACAAAGCAAGATTTAAACGCATATCAAATTTTTGATGTGCGCACTCCTTTAGAA
TGGGAAGAAGGTATTTTACC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MQFQTEVNQLLQLMIHSLYSNKEIFLRELISNASDALDKLNFLSVSDDKYKSLKFEPKIEIKIDKDKKTLSISDNGIGMD
KDDLINNLGTIAKSGTKSFLENLSGDAKKDSQLIGQFGVGFYSAFMVASKIEVLSKKALDDKAYLWSSDANGYEINDASK
EEQGTSITLYLKDDEFANTYKIESIIEKYSNHIQFPIFMEKEEFTPAKEGEEEGKTELKISQINKANALWRMQKSSLKAE
DYERFYEQNFHDSNKPLLYLHTKSEGKLEYNSLFFIPQNAPFDLFRVDYQSGLKLYVKRVFISDDDKELLPTYLRFVRGI
IDVEDLPLNVSREILQENQILKGVKEASVKKILGELEKLKNNDKEKYLSFFKTFGKVLKEGLYGFGGEKDSLLKLMLYKS
TKGENLRSLEEYKNDLQGEQKEIFYIAGNNESLLRTSPLLEEYKQKNIEVLLMDDEIDSLVTPMLEFEGLKFIAINQVED
KNELSDEEKNTFAPLVAKFKELLKDQVEDVRLTSRLKDSPSCIVYDKNKPDFAMQQLLKQMGQEQNFKPILEINPKHAIF
TGLKNNESFSADIATLVLNMAKLSEGMGVDNPAEFNASLTKIINKAFS

Sequences:

>Translated_608_residues
MQFQTEVNQLLQLMIHSLYSNKEIFLRELISNASDALDKLNFLSVSDDKYKSLKFEPKIEIKIDKDKKTLSISDNGIGMD
KDDLINNLGTIAKSGTKSFLENLSGDAKKDSQLIGQFGVGFYSAFMVASKIEVLSKKALDDKAYLWSSDANGYEINDASK
EEQGTSITLYLKDDEFANTYKIESIIEKYSNHIQFPIFMEKEEFTPAKEGEEEGKTELKISQINKANALWRMQKSSLKAE
DYERFYEQNFHDSNKPLLYLHTKSEGKLEYNSLFFIPQNAPFDLFRVDYQSGLKLYVKRVFISDDDKELLPTYLRFVRGI
IDVEDLPLNVSREILQENQILKGVKEASVKKILGELEKLKNNDKEKYLSFFKTFGKVLKEGLYGFGGEKDSLLKLMLYKS
TKGENLRSLEEYKNDLQGEQKEIFYIAGNNESLLRTSPLLEEYKQKNIEVLLMDDEIDSLVTPMLEFEGLKFIAINQVED
KNELSDEEKNTFAPLVAKFKELLKDQVEDVRLTSRLKDSPSCIVYDKNKPDFAMQQLLKQMGQEQNFKPILEINPKHAIF
TGLKNNESFSADIATLVLNMAKLSEGMGVDNPAEFNASLTKIINKAFS
>Mature_608_residues
MQFQTEVNQLLQLMIHSLYSNKEIFLRELISNASDALDKLNFLSVSDDKYKSLKFEPKIEIKIDKDKKTLSISDNGIGMD
KDDLINNLGTIAKSGTKSFLENLSGDAKKDSQLIGQFGVGFYSAFMVASKIEVLSKKALDDKAYLWSSDANGYEINDASK
EEQGTSITLYLKDDEFANTYKIESIIEKYSNHIQFPIFMEKEEFTPAKEGEEEGKTELKISQINKANALWRMQKSSLKAE
DYERFYEQNFHDSNKPLLYLHTKSEGKLEYNSLFFIPQNAPFDLFRVDYQSGLKLYVKRVFISDDDKELLPTYLRFVRGI
IDVEDLPLNVSREILQENQILKGVKEASVKKILGELEKLKNNDKEKYLSFFKTFGKVLKEGLYGFGGEKDSLLKLMLYKS
TKGENLRSLEEYKNDLQGEQKEIFYIAGNNESLLRTSPLLEEYKQKNIEVLLMDDEIDSLVTPMLEFEGLKFIAINQVED
KNELSDEEKNTFAPLVAKFKELLKDQVEDVRLTSRLKDSPSCIVYDKNKPDFAMQQLLKQMGQEQNFKPILEINPKHAIF
TGLKNNESFSADIATLVLNMAKLSEGMGVDNPAEFNASLTKIINKAFS

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=672, Percent_Identity=35.7142857142857, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI155722983, Length=638, Percent_Identity=34.1692789968652, Blast_Score=350, Evalue=2e-96,
Organism=Homo sapiens, GI4507677, Length=205, Percent_Identity=47.3170731707317, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI153792590, Length=207, Percent_Identity=49.7584541062802, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI154146191, Length=207, Percent_Identity=49.7584541062802, Blast_Score=182, Evalue=8e-46,
Organism=Escherichia coli, GI1786679, Length=621, Percent_Identity=43.6392914653784, Blast_Score=504, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17559162, Length=658, Percent_Identity=35.7142857142857, Blast_Score=367, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17542208, Length=667, Percent_Identity=34.0329835082459, Blast_Score=342, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI115535205, Length=628, Percent_Identity=33.9171974522293, Blast_Score=301, Evalue=8e-82,
Organism=Caenorhabditis elegans, GI115535167, Length=431, Percent_Identity=38.0510440835267, Blast_Score=263, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6325016, Length=676, Percent_Identity=37.1301775147929, Blast_Score=382, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6323840, Length=672, Percent_Identity=36.6071428571429, Blast_Score=377, Evalue=1e-105,
Organism=Drosophila melanogaster, GI21357739, Length=672, Percent_Identity=35.7142857142857, Blast_Score=377, Evalue=1e-104,
Organism=Drosophila melanogaster, GI17647529, Length=672, Percent_Identity=35.7142857142857, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24586016, Length=647, Percent_Identity=34.0030911901082, Blast_Score=335, Evalue=7e-92,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 69641; Mature: 69641

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFQTEVNQLLQLMIHSLYSNKEIFLRELISNASDALDKLNFLSVSDDKYKSLKFEPKIE
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHCEECCCEEE
IKIDKDKKTLSISDNGIGMDKDDLINNLGTIAKSGTKSFLENLSGDAKKDSQLIGQFGVG
EEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FYSAFMVASKIEVLSKKALDDKAYLWSSDANGYEINDASKEEQGTSITLYLKDDEFANTY
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEECCCCCCCCCCCEEEEEEECCCCCCHH
KIESIIEKYSNHIQFPIFMEKEEFTPAKEGEEEGKTELKISQINKANALWRMQKSSLKAE
HHHHHHHHHHCCEECEEEECCCCCCCCCCCCCCCCCEEEHHHCCHHHHHHHHHHHCCCHH
DYERFYEQNFHDSNKPLLYLHTKSEGKLEYNSLFFIPQNAPFDLFRVDYQSGLKLYVKRV
HHHHHHHCCCCCCCCCEEEEEECCCCCEEECEEEEEECCCCCCEEEECHHHHHHHHHHHH
FISDDDKELLPTYLRFVRGIIDVEDLPLNVSREILQENQILKGVKEASVKKILGELEKLK
HCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNDKEKYLSFFKTFGKVLKEGLYGFGGEKDSLLKLMLYKSTKGENLRSLEEYKNDLQGEQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
KEIFYIAGNNESLLRTSPLLEEYKQKNIEVLLMDDEIDSLVTPMLEFEGLKFIAINQVED
EEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCEEEEEEECCCC
KNELSDEEKNTFAPLVAKFKELLKDQVEDVRLTSRLKDSPSCIVYDKNKPDFAMQQLLKQ
CHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
MGQEQNFKPILEINPKHAIFTGLKNNESFSADIATLVLNMAKLSEGMGVDNPAEFNASLT
HCCCCCCCCEEEECCCHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KIINKAFS
HHHHHHCC
>Mature Secondary Structure
MQFQTEVNQLLQLMIHSLYSNKEIFLRELISNASDALDKLNFLSVSDDKYKSLKFEPKIE
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHCEECCCEEE
IKIDKDKKTLSISDNGIGMDKDDLINNLGTIAKSGTKSFLENLSGDAKKDSQLIGQFGVG
EEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FYSAFMVASKIEVLSKKALDDKAYLWSSDANGYEINDASKEEQGTSITLYLKDDEFANTY
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEECCCCCCCCCCCEEEEEEECCCCCCHH
KIESIIEKYSNHIQFPIFMEKEEFTPAKEGEEEGKTELKISQINKANALWRMQKSSLKAE
HHHHHHHHHHCCEECEEEECCCCCCCCCCCCCCCCCEEEHHHCCHHHHHHHHHHHCCCHH
DYERFYEQNFHDSNKPLLYLHTKSEGKLEYNSLFFIPQNAPFDLFRVDYQSGLKLYVKRV
HHHHHHHCCCCCCCCCEEEEEECCCCCEEECEEEEEECCCCCCEEEECHHHHHHHHHHHH
FISDDDKELLPTYLRFVRGIIDVEDLPLNVSREILQENQILKGVKEASVKKILGELEKLK
HCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNDKEKYLSFFKTFGKVLKEGLYGFGGEKDSLLKLMLYKSTKGENLRSLEEYKNDLQGEQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
KEIFYIAGNNESLLRTSPLLEEYKQKNIEVLLMDDEIDSLVTPMLEFEGLKFIAINQVED
EEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCEEEEEEECCCC
KNELSDEEKNTFAPLVAKFKELLKDQVEDVRLTSRLKDSPSCIVYDKNKPDFAMQQLLKQ
CHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
MGQEQNFKPILEINPKHAIFTGLKNNESFSADIATLVLNMAKLSEGMGVDNPAEFNASLT
HCCCCCCCCEEEECCCHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KIINKAFS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA