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The map label for this gene is thiJ [H]

Identifier: 57237728

GI number: 57237728

Start: 918125

End: 918694

Strand: Reverse

Name: thiJ [H]

Synonym: CJE0978

Alternate gene names: 57237728

Gene position: 918694-918125 (Counterclockwise)

Preceding gene: 57237729

Following gene: 57237726

Centisome position: 51.67

GC content: 32.28

Gene sequence:

>570_bases
ATGAGTAAAAAAGTATTAATTCCATTGGCTCAAGGTTTTGAAGAAGCTGAATTTATAGGAATTGCAGATGTTTTAAAACG
AGCAAAAGAATTAAATCCAGATTTGGAAGTTGTTATAGCTTCGTTAAACAGTGAGTTATTGGTAAAAGGTGCTAATAGCA
TTAGTATAAAAGCAGATTGTTCTATAGAGGATGTTGATATAGAAAATTTAGATGCTATTGCTTTGGCGGGTGGCTTTGAA
GGTATGATGAATCTTAAGAATTCAAATGTTATTTTAAATATCATTAAACAACTTCATAGCAAAAATAAAATTGTTGCCGC
AATCTGTGCTTCTCCTATAGTTTTAAATGAAGCAGGTGTTTTAGAGGGCGAGTTTGCTTGTTATCCTAGTTGTGAAGTTG
GACTTAATGGAAATCGTGTTAACAAGGCTGTAGTTGTAAATAAAAATGTTATAACTTCAGCAGGTCCAGCTACGGCAATT
CTTTTTGGTTTAGAACTAGCTAAAAAGTTATGCGGTGATGAAATTTATCAAAAATTATATGAGGGAATGTTGCTACCTTT
GACAAAATAG

Upstream 100 bases:

>100_bases
TTTTTAATGATTGTTTTGGTTATAGGTTTCAATCATCAAATGATGCAAAAAAACAAAGAAAGAGAAGAAAGATTTAAAAA
ATATAAAAAAGGAGAACAAA

Downstream 100 bases:

>100_bases
TTTAAATGGTAGTTTTTCTACCATTTAAACTAAAATAAAGCTTGAGGATTTTCTTTTTTTGTTTTTTCCTTAGGCAGTTC
AAAACCTCCAAGCATATGAA

Product: 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MSKKVLIPLAQGFEEAEFIGIADVLKRAKELNPDLEVVIASLNSELLVKGANSISIKADCSIEDVDIENLDAIALAGGFE
GMMNLKNSNVILNIIKQLHSKNKIVAAICASPIVLNEAGVLEGEFACYPSCEVGLNGNRVNKAVVVNKNVITSAGPATAI
LFGLELAKKLCGDEIYQKLYEGMLLPLTK

Sequences:

>Translated_189_residues
MSKKVLIPLAQGFEEAEFIGIADVLKRAKELNPDLEVVIASLNSELLVKGANSISIKADCSIEDVDIENLDAIALAGGFE
GMMNLKNSNVILNIIKQLHSKNKIVAAICASPIVLNEAGVLEGEFACYPSCEVGLNGNRVNKAVVVNKNVITSAGPATAI
LFGLELAKKLCGDEIYQKLYEGMLLPLTK
>Mature_188_residues
SKKVLIPLAQGFEEAEFIGIADVLKRAKELNPDLEVVIASLNSELLVKGANSISIKADCSIEDVDIENLDAIALAGGFEG
MMNLKNSNVILNIIKQLHSKNKIVAAICASPIVLNEAGVLEGEFACYPSCEVGLNGNRVNKAVVVNKNVITSAGPATAIL
FGLELAKKLCGDEIYQKLYEGMLLPLTK

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=195, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI31543380, Length=195, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI87081736, Length=181, Percent_Identity=32.5966850828729, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531319, Length=192, Percent_Identity=34.375, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17558714, Length=184, Percent_Identity=30.4347826086957, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI28571932, Length=189, Percent_Identity=37.5661375661376, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24653499, Length=189, Percent_Identity=34.9206349206349, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20155; Mature: 20024

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKVLIPLAQGFEEAEFIGIADVLKRAKELNPDLEVVIASLNSELLVKGANSISIKADC
CCCEEEEHHHCCCCHHHEECHHHHHHHHHHCCCCHHEEEECCCCEEEEECCCEEEEEECC
SIEDVDIENLDAIALAGGFEGMMNLKNSNVILNIIKQLHSKNKIVAAICASPIVLNEAGV
CEEECCCCCCCEEEEECCCHHHEECCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCCCC
LEGEFACYPSCEVGLNGNRVNKAVVVNKNVITSAGPATAILFGLELAKKLCGDEIYQKLY
CCCCEEECCCCEECCCCCCCCEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EGMLLPLTK
CCEECCCCC
>Mature Secondary Structure 
SKKVLIPLAQGFEEAEFIGIADVLKRAKELNPDLEVVIASLNSELLVKGANSISIKADC
CCEEEEHHHCCCCHHHEECHHHHHHHHHHCCCCHHEEEECCCCEEEEECCCEEEEEECC
SIEDVDIENLDAIALAGGFEGMMNLKNSNVILNIIKQLHSKNKIVAAICASPIVLNEAGV
CEEECCCCCCCEEEEECCCHHHEECCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCCCC
LEGEFACYPSCEVGLNGNRVNKAVVVNKNVITSAGPATAILFGLELAKKLCGDEIYQKLY
CCCCEEECCCCEECCCCCCCCEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EGMLLPLTK
CCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]