Click here to switch to the map view.

The map label for this gene is murA [H]

Identifier: 57237699

GI number: 57237699

Start: 882041

End: 883297

Strand: Reverse

Name: murA [H]

Synonym: CJE0945

Alternate gene names: 57237699

Gene position: 883297-882041 (Counterclockwise)

Preceding gene: 57237700

Following gene: 57237698

Centisome position: 49.68

GC content: 36.04

Gene sequence:

>1257_bases
ATGACTTATCTAGAAATCGAAGGCACAAATCATCTAAGCGGAAATGTTACAATAAGCGGGGCAAAAAATGCTGCCCTACC
CTTGATCGTTTCAAGCATACTTGCCAAAAATGAAGTAAAAATCAACAATGTTCCTAATGTGGCTGATATAAAAACTCTTA
TATCTTTGCTAGAAAATTTAGGAGCTAAAGTCAATTTTCAAAACAATAGTGCTTTATTAAACACAAACACTCTTAATCAA
ACCATAGCTAAATATGACATTGTGCGTAAAATGCGTGCTTCCATACTTACTCTAGGACCTTTACTTGCTCGTTTTGGGCA
TTGTGAAGTATCTTTGCCTGGTGGATGTGCCATAGGACAAAGACCTATTGATTTACATCTTTTAGCCTTGGAAAAAATGG
GGGCAAATATACAAATTAAACAAGGCTATGTCGTAGCTAGTGGAAATTTAAAAGGCAATGAAATTCTTTTTGATAAAATC
ACGGTTACAGGTAGCGAAAACATCATCATGGCAGCAGCTTTAGCTAAAGGTAAAACCAAGCTCTTAAATGTTGCAAAAGA
ACCCGAAGTAGTTCAACTTTGCGAAGTTTTAAAAGACGCAGGACTTGAAATTAAAGGCATAGGTACAGATGAACTTGAAA
TTTATGGTAGCGATGGAGAACTTTTAGAATTTAAAGAATTTAGCGTTATACCTGATAGAATTGAGGCAGGAACTTATCTT
TGTGCAGGGGCTATTACAAATTCTAAAATTACTTTAGATAAAGTTAACGCCACTCATCTTAGTGCAGTTTTAGCAAAACT
TCATCAAATGGGTTTTGAAACTTTGATTGCAGAAGATAGTATCACCCTACTTCCTGCTAAAGAAATTAAACCTGTAGAAA
TCATGACAAGTGAATATCCAGGCTTTCCAACCGATATGCAAGCGCAGTTTATGGCACTAGCTTTAAAGGCTAATGGAACT
AGCATTATCGATGAAAGACTATTTGAAAATCGCTTCATGCATGTAAGCGAACTCTTAAGAATGGGTGCAGATATTAAACT
CAACGGTCATATTGCTACTATAGTAGGCGGAAAAGAACTTAACGCTGCTGATGTCATGGCTACAGATTTGCGTGCTTCTT
CAGCCCTTATCTTAGCAGCTCTTGCAGCTAAAGGCACAAGCAAAGTCCATAGAATTTATCATCTTGATAGAGGTTATGAA
AATTTAGAAGAAAAATTTAAAGGTTTAGGTGTTAAAATCACAAGGCTTGAAGAATGA

Upstream 100 bases:

>100_bases
CTCAAATTCAAGAACTCCAAAGTCAACAAGCTTGATTATATTTTTTCAAAAGTTTAAGAATGCTATAATGATGCATTTTT
AAACTTTTTCAAGGAAAAAT

Downstream 100 bases:

>100_bases
AAAATATCTTTAAAACCTTAAAAGACTTAGAAAATCAAATTTCATGCTTAGATGAAAGTGAGCTTATTAGCCTTGAAAAA
GCAAAGGATAGAATTTTAGC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MTYLEIEGTNHLSGNVTISGAKNAALPLIVSSILAKNEVKINNVPNVADIKTLISLLENLGAKVNFQNNSALLNTNTLNQ
TIAKYDIVRKMRASILTLGPLLARFGHCEVSLPGGCAIGQRPIDLHLLALEKMGANIQIKQGYVVASGNLKGNEILFDKI
TVTGSENIIMAAALAKGKTKLLNVAKEPEVVQLCEVLKDAGLEIKGIGTDELEIYGSDGELLEFKEFSVIPDRIEAGTYL
CAGAITNSKITLDKVNATHLSAVLAKLHQMGFETLIAEDSITLLPAKEIKPVEIMTSEYPGFPTDMQAQFMALALKANGT
SIIDERLFENRFMHVSELLRMGADIKLNGHIATIVGGKELNAADVMATDLRASSALILAALAAKGTSKVHRIYHLDRGYE
NLEEKFKGLGVKITRLEE

Sequences:

>Translated_418_residues
MTYLEIEGTNHLSGNVTISGAKNAALPLIVSSILAKNEVKINNVPNVADIKTLISLLENLGAKVNFQNNSALLNTNTLNQ
TIAKYDIVRKMRASILTLGPLLARFGHCEVSLPGGCAIGQRPIDLHLLALEKMGANIQIKQGYVVASGNLKGNEILFDKI
TVTGSENIIMAAALAKGKTKLLNVAKEPEVVQLCEVLKDAGLEIKGIGTDELEIYGSDGELLEFKEFSVIPDRIEAGTYL
CAGAITNSKITLDKVNATHLSAVLAKLHQMGFETLIAEDSITLLPAKEIKPVEIMTSEYPGFPTDMQAQFMALALKANGT
SIIDERLFENRFMHVSELLRMGADIKLNGHIATIVGGKELNAADVMATDLRASSALILAALAAKGTSKVHRIYHLDRGYE
NLEEKFKGLGVKITRLEE
>Mature_417_residues
TYLEIEGTNHLSGNVTISGAKNAALPLIVSSILAKNEVKINNVPNVADIKTLISLLENLGAKVNFQNNSALLNTNTLNQT
IAKYDIVRKMRASILTLGPLLARFGHCEVSLPGGCAIGQRPIDLHLLALEKMGANIQIKQGYVVASGNLKGNEILFDKIT
VTGSENIIMAAALAKGKTKLLNVAKEPEVVQLCEVLKDAGLEIKGIGTDELEIYGSDGELLEFKEFSVIPDRIEAGTYLC
AGAITNSKITLDKVNATHLSAVLAKLHQMGFETLIAEDSITLLPAKEIKPVEIMTSEYPGFPTDMQAQFMALALKANGTS
IIDERLFENRFMHVSELLRMGADIKLNGHIATIVGGKELNAADVMATDLRASSALILAALAAKGTSKVHRIYHLDRGYEN
LEEKFKGLGVKITRLEE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=48.3333333333333, Blast_Score=380, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45127; Mature: 44996

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYLEIEGTNHLSGNVTISGAKNAALPLIVSSILAKNEVKINNVPNVADIKTLISLLENL
CEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHC
GAKVNFQNNSALLNTNTLNQTIAKYDIVRKMRASILTLGPLLARFGHCEVSLPGGCAIGQ
CCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCC
RPIDLHLLALEKMGANIQIKQGYVVASGNLKGNEILFDKITVTGSENIIMAAALAKGKTK
CCCEEEEEEEECCCCCEEEECCEEEEECCCCCCEEEEEEEEEECCCCEEEEEEHHCCCHH
LLNVAKEPEVVQLCEVLKDAGLEIKGIGTDELEIYGSDGELLEFKEFSVIPDRIEAGTYL
HHHCCCCCHHHHHHHHHHHCCCEEEECCCCCEEEECCCCCEEEEECCCCCCCHHCCCCEE
CAGAITNSKITLDKVNATHLSAVLAKLHQMGFETLIAEDSITLLPAKEIKPVEIMTSEYP
EEEEECCCEEEEEECCHHHHHHHHHHHHHCCHHHEEECCCEEEEECCCCCCEEEEECCCC
GFPTDMQAQFMALALKANGTSIIDERLFENRFMHVSELLRMGADIKLNGHIATIVGGKEL
CCCCCHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCC
NAADVMATDLRASSALILAALAAKGTSKVHRIYHLDRGYENLEEKFKGLGVKITRLEE
CHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure 
TYLEIEGTNHLSGNVTISGAKNAALPLIVSSILAKNEVKINNVPNVADIKTLISLLENL
EEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHC
GAKVNFQNNSALLNTNTLNQTIAKYDIVRKMRASILTLGPLLARFGHCEVSLPGGCAIGQ
CCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCC
RPIDLHLLALEKMGANIQIKQGYVVASGNLKGNEILFDKITVTGSENIIMAAALAKGKTK
CCCEEEEEEEECCCCCEEEECCEEEEECCCCCCEEEEEEEEEECCCCEEEEEEHHCCCHH
LLNVAKEPEVVQLCEVLKDAGLEIKGIGTDELEIYGSDGELLEFKEFSVIPDRIEAGTYL
HHHCCCCCHHHHHHHHHHHCCCEEEECCCCCEEEECCCCCEEEEECCCCCCCHHCCCCEE
CAGAITNSKITLDKVNATHLSAVLAKLHQMGFETLIAEDSITLLPAKEIKPVEIMTSEYP
EEEEECCCEEEEEECCHHHHHHHHHHHHHCCHHHEEECCCEEEEECCCCCCEEEEECCCC
GFPTDMQAQFMALALKANGTSIIDERLFENRFMHVSELLRMGADIKLNGHIATIVGGKEL
CCCCCHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCC
NAADVMATDLRASSALILAALAAKGTSKVHRIYHLDRGYENLEEKFKGLGVKITRLEE
CHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA