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The map label for this gene is ycbL [C]

Identifier: 57237654

GI number: 57237654

Start: 839198

End: 839794

Strand: Reverse

Name: ycbL [C]

Synonym: CJE0900

Alternate gene names: 57237654

Gene position: 839794-839198 (Counterclockwise)

Preceding gene: 57237661

Following gene: 57237653

Centisome position: 47.24

GC content: 30.49

Gene sequence:

>597_bases
ATGCAAATTATCAAACAAGCTTGTGGAGCTTATGAGACAAATTGTTATATTTTATTTGGTGAGCATGGAGAAATTATAAT
TGATCCTGGTTTTGATGCGCTAAATTTCATCAAAAAACATGTAAAAAATCCTTTAGCGATTTTAAACACTCACGGACATT
ACGATCATGTTTGGGATAATGAAAAAGTAAAACAAGCCTATCAAATCCCCATTTATATTCATAAAAATGATACTTTTATG
CTTGAAGATCCTTTTAATCAAGGTTTTATGCCTAGCAAAGCGAATTATTTGATTGATGATGAAAATATCATTTCTATAGG
CGGACTTGACTTTAAATTTCACTTTTTACCAGGACATACACCAGGTTGCACTATGATAGAAATTGTAGGTAAAAATATCA
TGTTTAGTGGAGATTTTTTATTTTATAGAAGCATAGGAAGATGGGATTTTCCTTATTCAGATGCAAATTTAATGAAACAA
AGCTTAGAAAAAGTTATGACTTACAAAGAAGATTTTAAACTTTTGCCAGGACATGGACAAGAAACTACTTTAAAAGAAGA
GCAAGTCCATCTACCCTCTTGGCTTAGATATTTTTAA

Upstream 100 bases:

>100_bases
TTTTTCCGTAATCTTTTGCCAATCCATAAAACTTGCCTTTTAAAAATTTAATGTATAATTATATTTATTTAAGGCAAATT
TTTTATTAAAGAGGCAAAAA

Downstream 100 bases:

>100_bases
GGTATATTAAAATGGAATTAGATCAAATTTTATTATATGCTTTTATTTTTTTAAATCTTTTTGCCCTTTTTGGTTTATTT
TTGGGAAATAAAAAGAAAAA

Product: metallo-beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MQIIKQACGAYETNCYILFGEHGEIIIDPGFDALNFIKKHVKNPLAILNTHGHYDHVWDNEKVKQAYQIPIYIHKNDTFM
LEDPFNQGFMPSKANYLIDDENIISIGGLDFKFHFLPGHTPGCTMIEIVGKNIMFSGDFLFYRSIGRWDFPYSDANLMKQ
SLEKVMTYKEDFKLLPGHGQETTLKEEQVHLPSWLRYF

Sequences:

>Translated_198_residues
MQIIKQACGAYETNCYILFGEHGEIIIDPGFDALNFIKKHVKNPLAILNTHGHYDHVWDNEKVKQAYQIPIYIHKNDTFM
LEDPFNQGFMPSKANYLIDDENIISIGGLDFKFHFLPGHTPGCTMIEIVGKNIMFSGDFLFYRSIGRWDFPYSDANLMKQ
SLEKVMTYKEDFKLLPGHGQETTLKEEQVHLPSWLRYF
>Mature_198_residues
MQIIKQACGAYETNCYILFGEHGEIIIDPGFDALNFIKKHVKNPLAILNTHGHYDHVWDNEKVKQAYQIPIYIHKNDTFM
LEDPFNQGFMPSKANYLIDDENIISIGGLDFKFHFLPGHTPGCTMIEIVGKNIMFSGDFLFYRSIGRWDFPYSDANLMKQ
SLEKVMTYKEDFKLLPGHGQETTLKEEQVHLPSWLRYF

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Escherichia coli, GI1787158, Length=198, Percent_Identity=32.3232323232323, Blast_Score=97, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17538952, Length=177, Percent_Identity=29.3785310734463, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23031; Mature: 23031

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIIKQACGAYETNCYILFGEHGEIIIDPGFDALNFIKKHVKNPLAILNTHGHYDHVWDN
CCHHHHHCCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCCC
EKVKQAYQIPIYIHKNDTFMLEDPFNQGFMPSKANYLIDDENIISIGGLDFKFHFLPGHT
HHHHHEEEEEEEEECCCEEEEECCCCCCCCCCCCCEEECCCCEEEECCCEEEEEEECCCC
PGCTMIEIVGKNIMFSGDFLFYRSIGRWDFPYSDANLMKQSLEKVMTYKEDFKLLPGHGQ
CCCEEEEEECCCEEEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCC
ETTLKEEQVHLPSWLRYF
CCCCCHHHCCCCHHHHCC
>Mature Secondary Structure
MQIIKQACGAYETNCYILFGEHGEIIIDPGFDALNFIKKHVKNPLAILNTHGHYDHVWDN
CCHHHHHCCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCCC
EKVKQAYQIPIYIHKNDTFMLEDPFNQGFMPSKANYLIDDENIISIGGLDFKFHFLPGHT
HHHHHEEEEEEEEECCCEEEEECCCCCCCCCCCCCEEECCCCEEEECCCEEEEEEECCCC
PGCTMIEIVGKNIMFSGDFLFYRSIGRWDFPYSDANLMKQSLEKVMTYKEDFKLLPGHGQ
CCCEEEEEECCCEEEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCC
ETTLKEEQVHLPSWLRYF
CCCCCHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]