Click here to switch to the map view.

The map label for this gene is kdgR [H]

Identifier: 57237534

GI number: 57237534

Start: 485862

End: 486623

Strand: Reverse

Name: kdgR [H]

Synonym: CJE0530

Alternate gene names: 57237534

Gene position: 486623-485862 (Counterclockwise)

Preceding gene: 57237535

Following gene: 57237519

Centisome position: 27.37

GC content: 23.23

Gene sequence:

>762_bases
ATGCATCAGCCCACTCTTAGAGTGTTAAATATTCTAGAATTACTTGCAAAAGAAAAGCTTACCTTAAGTGCTATAGCTAA
AAAATTAAACATTCCTGCTGGAACTCTTTGGCCTATTTTACAAACTCTTCAAGAAAAAAAATATATCAAATGTGATTTAA
AAAATAAAAGTTATTATTTGGATTTTAAGATTATAGAATTAGGATGTAATATAAAAAATGAAAATAATATTTTTGAAATA
ATCAAAAAGCATATGAAAAATATAAGAAATTTAACCAATCAAACTTGTCAAATGGGAATTTTAAAAGATGGAAATGTGCT
TTATTTAGAAAAAATTGATGCCAATAATACAGTACAATTAAAATCTTTTATAGGCACTTCGTATCCTGCTTATGCAACAT
CTTTAGGCAAAGCCTTACTATCAAATAAAAATAAAAAGGAATTAGAAAAACTTTATCCTAGAAATTTTGATAAAATTACA
GAAAACACCTTAAATAATATAAATGAACTCTATCAACAAATCAAACAAATTAAAAAAGAAAAAATTGCCATAGAAATTGG
AGAAATGAATCCTCAAATTGAATGTATGGCTATAGGCATAGAACATAAAAATAAAATAATTGCTGCCATTAGTATATCTT
ATCTAATTTATTGCTCTAATAAAGCTTTTAGAGAAAAAAATAAAAAAATACTTCTAGAAGAAAAAAATAAAATAGAAAAA
GTTTTAAAAATTTATTTTAATGATTTAGATACACTGTATTAA

Upstream 100 bases:

>100_bases
AAAATATTAAAATTAATAAATAATAAAAATTATGATTTTATGTTACTAAAAGTAAAAAATATGCTAAAATTTATAAAAAT
AAAACAAGGATAAAGACAAT

Downstream 100 bases:

>100_bases
TATAGCCCCGAAGGGCTATAAAATAGAGTTTTATTCTTGTTCTTTAAGTTTTAAATTTTGTTCGCCATAAAGCCCTGTTC
CAACAGGAATCATTCTACCT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MHQPTLRVLNILELLAKEKLTLSAIAKKLNIPAGTLWPILQTLQEKKYIKCDLKNKSYYLDFKIIELGCNIKNENNIFEI
IKKHMKNIRNLTNQTCQMGILKDGNVLYLEKIDANNTVQLKSFIGTSYPAYATSLGKALLSNKNKKELEKLYPRNFDKIT
ENTLNNINELYQQIKQIKKEKIAIEIGEMNPQIECMAIGIEHKNKIIAAISISYLIYCSNKAFREKNKKILLEEKNKIEK
VLKIYFNDLDTLY

Sequences:

>Translated_253_residues
MHQPTLRVLNILELLAKEKLTLSAIAKKLNIPAGTLWPILQTLQEKKYIKCDLKNKSYYLDFKIIELGCNIKNENNIFEI
IKKHMKNIRNLTNQTCQMGILKDGNVLYLEKIDANNTVQLKSFIGTSYPAYATSLGKALLSNKNKKELEKLYPRNFDKIT
ENTLNNINELYQQIKQIKKEKIAIEIGEMNPQIECMAIGIEHKNKIIAAISISYLIYCSNKAFREKNKKILLEEKNKIEK
VLKIYFNDLDTLY
>Mature_253_residues
MHQPTLRVLNILELLAKEKLTLSAIAKKLNIPAGTLWPILQTLQEKKYIKCDLKNKSYYLDFKIIELGCNIKNENNIFEI
IKKHMKNIRNLTNQTCQMGILKDGNVLYLEKIDANNTVQLKSFIGTSYPAYATSLGKALLSNKNKKELEKLYPRNFDKIT
ENTLNNINELYQQIKQIKKEKIAIEIGEMNPQIECMAIGIEHKNKIIAAISISYLIYCSNKAFREKNKKILLEEKNKIEK
VLKIYFNDLDTLY

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=212, Percent_Identity=24.5283018867925, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786468, Length=232, Percent_Identity=28.8793103448276, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788581, Length=216, Percent_Identity=23.1481481481481, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790752, Length=173, Percent_Identity=30.0578034682081, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29344; Mature: 29344

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQPTLRVLNILELLAKEKLTLSAIAKKLNIPAGTLWPILQTLQEKKYIKCDLKNKSYYL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECCCEEEE
DFKIIELGCNIKNENNIFEIIKKHMKNIRNLTNQTCQMGILKDGNVLYLEKIDANNTVQL
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEECCCCEEEH
KSFIGTSYPAYATSLGKALLSNKNKKELEKLYPRNFDKITENTLNNINELYQQIKQIKKE
HHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KIAIEIGEMNPQIECMAIGIEHKNKIIAAISISYLIYCSNKAFREKNKKILLEEKNKIEK
HEEEEECCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCHHHHHCCCEEEEHHHHHHHH
VLKIYFNDLDTLY
HHHHHHHHHHHCC
>Mature Secondary Structure
MHQPTLRVLNILELLAKEKLTLSAIAKKLNIPAGTLWPILQTLQEKKYIKCDLKNKSYYL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECCCEEEE
DFKIIELGCNIKNENNIFEIIKKHMKNIRNLTNQTCQMGILKDGNVLYLEKIDANNTVQL
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEECCCCEEEH
KSFIGTSYPAYATSLGKALLSNKNKKELEKLYPRNFDKITENTLNNINELYQQIKQIKKE
HHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KIAIEIGEMNPQIECMAIGIEHKNKIIAAISISYLIYCSNKAFREKNKKILLEEKNKIEK
HEEEEECCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCHHHHHCCCEEEEHHHHHHHH
VLKIYFNDLDTLY
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]