Click here to switch to the map view.

The map label for this gene is polC [H]

Identifier: 57237506

GI number: 57237506

Start: 455855

End: 456556

Strand: Direct

Name: polC [H]

Synonym: CJE0502

Alternate gene names: 57237506

Gene position: 455855-456556 (Clockwise)

Preceding gene: 57237505

Following gene: 57237507

Centisome position: 25.64

GC content: 29.77

Gene sequence:

>702_bases
ATGCAAGAGTTTGCCAAAGTTGAAGAATTAAAAAATTTTGATTTAGATTTGGAAACTTTTGAGCTTTTGGGTTTGGGCTT
AACTTTGAATAAAGATAATATTTTTATCCTTAAAACACGCACAACAAAAATTAAAGATGAAATTTTTTGTATAGTAGATA
TAGAAAGTACTGGCGGTGTAAGCAAGGGGGAAATTTTAGAAATTGGAGCAGTAAAAATTCAAAATTCTAAAGAAATTGGA
CGCTTTCAAAGTTTTGTTAAAGTAAAAGAAATTCCAGAAAATATAACCGAACTTACGGGTATTACTTATGAGATGGTGGA
AAATGCTCCAAGTTTAACAAAGGTTTTAAGTGATTTTAGGCTTTTTTTAAAAGACAGTATTTTTGTAGCACATAATGTGC
GTTTTGATTATAGTTTTATTTCTAAGGCTTTAAATGAGTGTGGTTTTGGCATTTTACTTAATCGTCGTATTTGTACTATA
GAATTTGCACAATGTTGTATAGAAAGTCCAAAATATAAACTAGAGGTTTTGAAAGAATTTCTGGGCGTGGAAAATACGCA
TCATAGGGCTTTAGATGATGCTTTGGCAGCTGCTGAAATTTTTAAATATTGCCTTGGAAAACTTCCCTATCATATAAAAA
CTACAGAAGAACTTATAAATTTTACAAAGACTGCCACGCATAAAGCAAAAATAAATATTTAA

Upstream 100 bases:

>100_bases
AAACTGCAATTTCATCTTTAAAGCTTGAATTTTGAGTTTACAGCAAATTGATCAGATTATTTCTATATTAAACAAGCAAA
GCAAGCCTTATGATTGGGTG

Downstream 100 bases:

>100_bases
AGAGTATAATTAAGACATAAATGACGGGAGCTTGTGTAACAGGCTGAGAGTAAGCTAAAAGCTTAGACCGAACCGGATCT
GGATAATACCAGCGTCGGGA

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MQEFAKVEELKNFDLDLETFELLGLGLTLNKDNIFILKTRTTKIKDEIFCIVDIESTGGVSKGEILEIGAVKIQNSKEIG
RFQSFVKVKEIPENITELTGITYEMVENAPSLTKVLSDFRLFLKDSIFVAHNVRFDYSFISKALNECGFGILLNRRICTI
EFAQCCIESPKYKLEVLKEFLGVENTHHRALDDALAAAEIFKYCLGKLPYHIKTTEELINFTKTATHKAKINI

Sequences:

>Translated_233_residues
MQEFAKVEELKNFDLDLETFELLGLGLTLNKDNIFILKTRTTKIKDEIFCIVDIESTGGVSKGEILEIGAVKIQNSKEIG
RFQSFVKVKEIPENITELTGITYEMVENAPSLTKVLSDFRLFLKDSIFVAHNVRFDYSFISKALNECGFGILLNRRICTI
EFAQCCIESPKYKLEVLKEFLGVENTHHRALDDALAAAEIFKYCLGKLPYHIKTTEELINFTKTATHKAKINI
>Mature_233_residues
MQEFAKVEELKNFDLDLETFELLGLGLTLNKDNIFILKTRTTKIKDEIFCIVDIESTGGVSKGEILEIGAVKIQNSKEIG
RFQSFVKVKEIPENITELTGITYEMVENAPSLTKVLSDFRLFLKDSIFVAHNVRFDYSFISKALNECGFGILLNRRICTI
EFAQCCIESPKYKLEVLKEFLGVENTHHRALDDALAAAEIFKYCLGKLPYHIKTTEELINFTKTATHKAKINI

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR016027
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26510; Mature: 26510

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEFAKVEELKNFDLDLETFELLGLGLTLNKDNIFILKTRTTKIKDEIFCIVDIESTGGV
CCHHHHHHHHHCCCCCHHHHHHHEECEEECCCCEEEEEECCCCCCCEEEEEEEECCCCCC
SKGEILEIGAVKIQNSKEIGRFQSFVKVKEIPENITELTGITYEMVENAPSLTKVLSDFR
CCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHH
LFLKDSIFVAHNVRFDYSFISKALNECGFGILLNRRICTIEFAQCCIESPKYKLEVLKEF
HHHHCCEEEEEECEECHHHHHHHHHHCCCEEEECCEEEHHHHHHHHHCCCCHHHHHHHHH
LGVENTHHRALDDALAAAEIFKYCLGKLPYHIKTTEELINFTKTATHKAKINI
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure
MQEFAKVEELKNFDLDLETFELLGLGLTLNKDNIFILKTRTTKIKDEIFCIVDIESTGGV
CCHHHHHHHHHCCCCCHHHHHHHEECEEECCCCEEEEEECCCCCCCEEEEEEEECCCCCC
SKGEILEIGAVKIQNSKEIGRFQSFVKVKEIPENITELTGITYEMVENAPSLTKVLSDFR
CCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHH
LFLKDSIFVAHNVRFDYSFISKALNECGFGILLNRRICTIEFAQCCIESPKYKLEVLKEF
HHHHCCEEEEEECEECHHHHHHHHHHCCCEEEECCEEEHHHHHHHHHCCCCHHHHHHHHH
LGVENTHHRALDDALAAAEIFKYCLGKLPYHIKTTEELINFTKTATHKAKINI
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]