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The map label for this gene is nudK [H]

Identifier: 57237501

GI number: 57237501

Start: 452673

End: 453269

Strand: Direct

Name: nudK [H]

Synonym: CJE0497

Alternate gene names: 57237501

Gene position: 452673-453269 (Clockwise)

Preceding gene: 57237500

Following gene: 57237505

Centisome position: 25.46

GC content: 29.31

Gene sequence:

>597_bases
ATGGCGTTTAAAAATTTAAAAGAACTTTCTTTTGAAAAATCAAATTATATTAAGCCTAAGAGATTTGTTTATGAAAGTAA
TGGTAGGCTTTGCACTTGGGATTTTATAGAATCTAAAGATAGTGTTTCAGTGCTTTTGTATCATAAAGAATTAGAAAGTT
TTATTTTTGTACGCCAATTTCGTATACCACTTTGGTATCATCAAATGCATGATAAAGATTATGTAAAAGATGATGATATG
GGCTATACTATAGAGCTTTGTTCTGGGCTTGTGGATAAAAAATTATCTTTAGAGGAAATAGCAAAAGAAGAATGTATAGA
AGAACTAGGATATGCTCCTAAAAATTTAGAAAAAATAGGAGATTTTTATACAGGGTTTGGTTCAGGTGTAAGCAAGCAAA
GCTTTTATTTCGTAGAAGTTGATGAAAAAGATAAAATTTCTTCTGGAGGTGGAGTTGATGATGAAGAGATTGAAGCTGTT
TATGTTAAGGTACAGGATTTTGAAAAAAAATGTAAAAATATGATAAGAACGCCTTTGCTTGATTTTGCTTATATGTGGTT
TTTAAAGGAAAAGTGGGGAAAATTAAAGATTATTTAG

Upstream 100 bases:

>100_bases
TATAAATATGATTTTTAATTTTTTAAGGCTTTAATCACCTTTATATTTTCAAAAAAGCAAAAATAAAGTACAATGTGAAA
AATAAATAAAAGGTTTTATT

Downstream 100 bases:

>100_bases
GTTAAACCTTAAAAAGGTTCAACCTAGGATTTTAATGATCTGACTCATCAAGCATTTCTTTAAATACATTGAAAAGATCA
AGCGATGCATTTTCAGCAAC

Product: NUDIX domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MAFKNLKELSFEKSNYIKPKRFVYESNGRLCTWDFIESKDSVSVLLYHKELESFIFVRQFRIPLWYHQMHDKDYVKDDDM
GYTIELCSGLVDKKLSLEEIAKEECIEELGYAPKNLEKIGDFYTGFGSGVSKQSFYFVEVDEKDKISSGGGVDDEEIEAV
YVKVQDFEKKCKNMIRTPLLDFAYMWFLKEKWGKLKII

Sequences:

>Translated_198_residues
MAFKNLKELSFEKSNYIKPKRFVYESNGRLCTWDFIESKDSVSVLLYHKELESFIFVRQFRIPLWYHQMHDKDYVKDDDM
GYTIELCSGLVDKKLSLEEIAKEECIEELGYAPKNLEKIGDFYTGFGSGVSKQSFYFVEVDEKDKISSGGGVDDEEIEAV
YVKVQDFEKKCKNMIRTPLLDFAYMWFLKEKWGKLKII
>Mature_197_residues
AFKNLKELSFEKSNYIKPKRFVYESNGRLCTWDFIESKDSVSVLLYHKELESFIFVRQFRIPLWYHQMHDKDYVKDDDMG
YTIELCSGLVDKKLSLEEIAKEECIEELGYAPKNLEKIGDFYTGFGSGVSKQSFYFVEVDEKDKISSGGGVDDEEIEAVY
VKVQDFEKKCKNMIRTPLLDFAYMWFLKEKWGKLKII

Specific function: Catalyzes the hydrolysis of GDP-mannose [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI37594467, Length=201, Percent_Identity=31.3432835820896, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI1788810, Length=153, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17558808, Length=213, Percent_Identity=35.6807511737089, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24650557, Length=194, Percent_Identity=35.5670103092784, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23340; Mature: 23209

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFKNLKELSFEKSNYIKPKRFVYESNGRLCTWDFIESKDSVSVLLYHKELESFIFVRQF
CCCCHHHHHCCCCCCCCCCHHEEEECCCCEEEEHHHCCCCCEEEEEEHHHHHHHHHHHHH
RIPLWYHQMHDKDYVKDDDMGYTIELCSGLVDKKLSLEEIAKEECIEELGYAPKNLEKIG
CCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
DFYTGFGSGVSKQSFYFVEVDEKDKISSGGGVDDEEIEAVYVKVQDFEKKCKNMIRTPLL
HHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHEEEEEEEHHHHHHHHHHHHHHHHH
DFAYMWFLKEKWGKLKII
HHHHHHHHHHCCCCEECC
>Mature Secondary Structure 
AFKNLKELSFEKSNYIKPKRFVYESNGRLCTWDFIESKDSVSVLLYHKELESFIFVRQF
CCCHHHHHCCCCCCCCCCHHEEEECCCCEEEEHHHCCCCCEEEEEEHHHHHHHHHHHHH
RIPLWYHQMHDKDYVKDDDMGYTIELCSGLVDKKLSLEEIAKEECIEELGYAPKNLEKIG
CCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
DFYTGFGSGVSKQSFYFVEVDEKDKISSGGGVDDEEIEAVYVKVQDFEKKCKNMIRTPLL
HHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHEEEEEEEHHHHHHHHHHHHHHHHH
DFAYMWFLKEKWGKLKII
HHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA