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The map label for this gene is 57237470

Identifier: 57237470

GI number: 57237470

Start: 419351

End: 421072

Strand: Direct

Name: 57237470

Synonym: CJE0464

Alternate gene names: NA

Gene position: 419351-421072 (Clockwise)

Preceding gene: 57237469

Following gene: 57237472

Centisome position: 23.59

GC content: 37.17

Gene sequence:

>1722_bases
ATGGCTGAAGTATTAAAAAAAGTAGATGTGGTAACAGTTGGGGCAGGATGGACTGGAGGTATAGTGGCTGCAGAGCTTAC
TAAAGCAGGTTTGAATGTACTTAGTTTAGAACGCGGACATATGCAAAGTACTGAAAATTTTAATTTTATCCATGATGAGT
GGAGATACGGGATTAATTATGGTTTGATGCAAGATTGCTCGAAAGACACTGTGACTTTTCGCCATGATCCTAGTGGTTTA
GCCTTGCCTTATCGTAAAATGGGTTCGTTTTTATTGGGTAATAATGTTGGCGGTGCAGGGGTGCATTGGAATGGTTGGAC
TTTTAGGTTTATGCCTTATGATTTTGAAATTCAAACCCTAAGCAAACAAAGATATGGTAATAAATTAGGTAATGATTATA
CCTTGCAAGATTGGGGTGTGACTTATAAGGATATGGAGCCTTATTATGATAGATTTGAAAAAACCTGTGGGGTATCAGGT
GAGCCAAATCCTTTAGCGGAAAAAATGGGAGCTTTTAGATCCAGTCCTTATCCACAAGAACCTCTTGAAAATACTAAAAT
GCTTAAACGATTTGAAAGTGCAGCAAAAAGTTCAAATTTACACACTTATCGTTTGCCAGCTTCAAATTCTAAAGGTGGCT
ATACAAACCCTGATGGTCAAGATTTAGCTCCTTGTCAATACTGTGCGTATTGTGAGCGTTTTGGTTGTGAGTATGGCGCA
AAAGCAAGTCCTTTAAACACAGTAATTCCAAAGGCTATGAGCACAGGTAAATACACTATACGCACTTATAGCAATGTAAC
GCAAATTCTTAAAAAAGACGGAAAAGTAACGGGGGTAAAATTTGTCGATACTAGAACGATGAAAGAGTATATTCAACCTG
CTGATATAGTTGTGCTTACAAGTTATATGTTTAACAATGCTAAGCTTTTAATGGTAAGCAACATAGGTGAGCAATACGAT
CCAAAAACAGGTAAAGGAACTTTAGGTAGAAATTATTGTTATCAAATGAACATGGGTACAACAGCTTTCTTTGATGAGCA
ATTTAACACCTTCATGGGTTCAGGTGCTTTGGGAACTACGAGTGATGATTTTAACGGAGATAATTTTGATCATTCTAGGG
AAAAATTCCTTCATGGAGCTATGATTTATAGCGTTCAGCTTGGAACTCGCCCTATACAATCAGCCCCACTTCCAGCAGGA
GCTCCAACTTGGGGTGCTGAATTTAAAAAAGCATTAAACTATAATTTCACAAGAGCTATTACCGTAGCAGGACAAGGTGC
TTCTTTGCCTCATAAGAATAATTATTTAAGTCTTGATCCAACTTATAAAGATGCTTTTGGTATGCCACTTTTACGCTTAA
CTTATAATTTCACCGATCAAGATAGAGCTTTGCATAAATTTATCACAGATAAAACAGCTGAGGTAGCAAAAAGAATGCAA
GGAGTAAAATCAATCAAAAAAGGTGCTTATCTTAAGGATTATAGCGTTGTGCCTTATCAATCTACTCATAACACAGGTGG
AACAACCATGGGTGCAGATAGAGAAACTAGTGTGGTTAATACTTATTTACAACACTGGGATGCGGATAATCTTTTTGTTG
TAGGAGCAGGAAATTTCCAACACAATAGTGGATATAATCCAACTGATACTGTAGGAGCTTTGGCTTATCGCTGTGCTGAA
GGTATTTTAAAGTATCATAAAAGTGGAAAAAGCTTAGCTTGA

Upstream 100 bases:

>100_bases
ATGCAATATCCAGGCGCACAAATGAGCTATGTGGATAAAATTGCAAGTGATGAATTTTTTAACATTGAACCTATGAGTTT
AGCAGATATGGAGAGTTAAA

Downstream 100 bases:

>100_bases
TAATAACTTGAGAGTTTTTGAAAACTCTCAAGATTATAAATTTTTAATTTTCTTCCGATATAGTATAATATCAAGGAAGG
CAAAAATGATTAATGGTATA

Product: oxidoreductase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MAEVLKKVDVVTVGAGWTGGIVAAELTKAGLNVLSLERGHMQSTENFNFIHDEWRYGINYGLMQDCSKDTVTFRHDPSGL
ALPYRKMGSFLLGNNVGGAGVHWNGWTFRFMPYDFEIQTLSKQRYGNKLGNDYTLQDWGVTYKDMEPYYDRFEKTCGVSG
EPNPLAEKMGAFRSSPYPQEPLENTKMLKRFESAAKSSNLHTYRLPASNSKGGYTNPDGQDLAPCQYCAYCERFGCEYGA
KASPLNTVIPKAMSTGKYTIRTYSNVTQILKKDGKVTGVKFVDTRTMKEYIQPADIVVLTSYMFNNAKLLMVSNIGEQYD
PKTGKGTLGRNYCYQMNMGTTAFFDEQFNTFMGSGALGTTSDDFNGDNFDHSREKFLHGAMIYSVQLGTRPIQSAPLPAG
APTWGAEFKKALNYNFTRAITVAGQGASLPHKNNYLSLDPTYKDAFGMPLLRLTYNFTDQDRALHKFITDKTAEVAKRMQ
GVKSIKKGAYLKDYSVVPYQSTHNTGGTTMGADRETSVVNTYLQHWDADNLFVVGAGNFQHNSGYNPTDTVGALAYRCAE
GILKYHKSGKSLA

Sequences:

>Translated_573_residues
MAEVLKKVDVVTVGAGWTGGIVAAELTKAGLNVLSLERGHMQSTENFNFIHDEWRYGINYGLMQDCSKDTVTFRHDPSGL
ALPYRKMGSFLLGNNVGGAGVHWNGWTFRFMPYDFEIQTLSKQRYGNKLGNDYTLQDWGVTYKDMEPYYDRFEKTCGVSG
EPNPLAEKMGAFRSSPYPQEPLENTKMLKRFESAAKSSNLHTYRLPASNSKGGYTNPDGQDLAPCQYCAYCERFGCEYGA
KASPLNTVIPKAMSTGKYTIRTYSNVTQILKKDGKVTGVKFVDTRTMKEYIQPADIVVLTSYMFNNAKLLMVSNIGEQYD
PKTGKGTLGRNYCYQMNMGTTAFFDEQFNTFMGSGALGTTSDDFNGDNFDHSREKFLHGAMIYSVQLGTRPIQSAPLPAG
APTWGAEFKKALNYNFTRAITVAGQGASLPHKNNYLSLDPTYKDAFGMPLLRLTYNFTDQDRALHKFITDKTAEVAKRMQ
GVKSIKKGAYLKDYSVVPYQSTHNTGGTTMGADRETSVVNTYLQHWDADNLFVVGAGNFQHNSGYNPTDTVGALAYRCAE
GILKYHKSGKSLA
>Mature_572_residues
AEVLKKVDVVTVGAGWTGGIVAAELTKAGLNVLSLERGHMQSTENFNFIHDEWRYGINYGLMQDCSKDTVTFRHDPSGLA
LPYRKMGSFLLGNNVGGAGVHWNGWTFRFMPYDFEIQTLSKQRYGNKLGNDYTLQDWGVTYKDMEPYYDRFEKTCGVSGE
PNPLAEKMGAFRSSPYPQEPLENTKMLKRFESAAKSSNLHTYRLPASNSKGGYTNPDGQDLAPCQYCAYCERFGCEYGAK
ASPLNTVIPKAMSTGKYTIRTYSNVTQILKKDGKVTGVKFVDTRTMKEYIQPADIVVLTSYMFNNAKLLMVSNIGEQYDP
KTGKGTLGRNYCYQMNMGTTAFFDEQFNTFMGSGALGTTSDDFNGDNFDHSREKFLHGAMIYSVQLGTRPIQSAPLPAGA
PTWGAEFKKALNYNFTRAITVAGQGASLPHKNNYLSLDPTYKDAFGMPLLRLTYNFTDQDRALHKFITDKTAEVAKRMQG
VKSIKKGAYLKDYSVVPYQSTHNTGGTTMGADRETSVVNTYLQHWDADNLFVVGAGNFQHNSGYNPTDTVGALAYRCAEG
ILKYHKSGKSLA

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 63712; Mature: 63581

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVLKKVDVVTVGAGWTGGIVAAELTKAGLNVLSLERGHMQSTENFNFIHDEWRYGINY
CHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCEEHHHHHCCCCC
GLMQDCSKDTVTFRHDPSGLALPYRKMGSFLLGNNVGGAGVHWNGWTFRFMPYDFEIQTL
CHHHCCCCCCEEEEECCCCCCCCHHHHCCEEECCCCCCCCEEECCEEEEEECCCEEEHHH
SKQRYGNKLGNDYTLQDWGVTYKDMEPYYDRFEKTCGVSGEPNPLAEKMGAFRSSPYPQE
HHHHHHHHCCCCCEECCCCCCHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
PLENTKMLKRFESAAKSSNLHTYRLPASNSKGGYTNPDGQDLAPCQYCAYCERFGCEYGA
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
KASPLNTVIPKAMSTGKYTIRTYSNVTQILKKDGKVTGVKFVDTRTMKEYIQPADIVVLT
CCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCEEEEEEECHHHHHHHCCCCCEEEEE
SYMFNNAKLLMVSNIGEQYDPKTGKGTLGRNYCYQMNMGTTAFFDEQFNTFMGSGALGTT
EHHHCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHCCCCCCCC
SDDFNGDNFDHSREKFLHGAMIYSVQLGTRPIQSAPLPAGAPTWGAEFKKALNYNFTRAI
CCCCCCCCCCHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEE
TVAGQGASLPHKNNYLSLDPTYKDAFGMPLLRLTYNFTDQDRALHKFITDKTAEVAKRMQ
EEECCCCCCCCCCCEEEECCCHHHHHCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHH
GVKSIKKGAYLKDYSVVPYQSTHNTGGTTMGADRETSVVNTYLQHWDADNLFVVGAGNFQ
HHHHHHCCCEEECCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCC
HNSGYNPTDTVGALAYRCAEGILKYHKSGKSLA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AEVLKKVDVVTVGAGWTGGIVAAELTKAGLNVLSLERGHMQSTENFNFIHDEWRYGINY
HHHHHHCCEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCEEHHHHHCCCCC
GLMQDCSKDTVTFRHDPSGLALPYRKMGSFLLGNNVGGAGVHWNGWTFRFMPYDFEIQTL
CHHHCCCCCCEEEEECCCCCCCCHHHHCCEEECCCCCCCCEEECCEEEEEECCCEEEHHH
SKQRYGNKLGNDYTLQDWGVTYKDMEPYYDRFEKTCGVSGEPNPLAEKMGAFRSSPYPQE
HHHHHHHHCCCCCEECCCCCCHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
PLENTKMLKRFESAAKSSNLHTYRLPASNSKGGYTNPDGQDLAPCQYCAYCERFGCEYGA
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
KASPLNTVIPKAMSTGKYTIRTYSNVTQILKKDGKVTGVKFVDTRTMKEYIQPADIVVLT
CCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCEEEEEEECHHHHHHHCCCCCEEEEE
SYMFNNAKLLMVSNIGEQYDPKTGKGTLGRNYCYQMNMGTTAFFDEQFNTFMGSGALGTT
EHHHCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHCCCCCCCC
SDDFNGDNFDHSREKFLHGAMIYSVQLGTRPIQSAPLPAGAPTWGAEFKKALNYNFTRAI
CCCCCCCCCCHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEE
TVAGQGASLPHKNNYLSLDPTYKDAFGMPLLRLTYNFTDQDRALHKFITDKTAEVAKRMQ
EEECCCCCCCCCCCEEEECCCHHHHHCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHH
GVKSIKKGAYLKDYSVVPYQSTHNTGGTTMGADRETSVVNTYLQHWDADNLFVVGAGNFQ
HHHHHHCCCEEECCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCC
HNSGYNPTDTVGALAYRCAEGILKYHKSGKSLA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]