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The map label for this gene is lspA [H]

Identifier: 57237416

GI number: 57237416

Start: 366159

End: 366629

Strand: Direct

Name: lspA [H]

Synonym: CJE0410

Alternate gene names: 57237416

Gene position: 366159-366629 (Clockwise)

Preceding gene: 57237415

Following gene: 57237417

Centisome position: 20.6

GC content: 29.51

Gene sequence:

>471_bases
ATGGCTAAAACTTTTAAATTTATTTTTTATTTTTGGGGTGCCTTTGTTTTGGTTTTTGCCCTTGATCAATGGGTAAAATC
CTTAACTTTAGCAGGATTTAGATGGCAGAGTGAATACCTAGATTTAACTTATGCTCTAAATACAGGCGTAGCTTTTTCAA
TGTTGAGTTTTTTAGAACATAATTTAAAATATTTACATCTTGCTTTAATTGGCGTGCTTTTTATTTATCTTTTTTGGCAA
AGAACACTTTTAAAAACTCATAGCATAGCTTTTGGAATGATGCTTGGTGCCGGCGTTTCAAATTTATTGGATCGTTTTAT
ACATGGAGGTGTAGTGGATATGTTTTTTTGGCATAAATGGTTTAATTTTGCTATTTTTAATGTTGCAGATGTCATGATAA
ATATAAGTGTGGCTTTGATTTTAATACAAGAAATATTTAAAAAAAGGAAAAAAGATGACAGAATGGATTAA

Upstream 100 bases:

>100_bases
GGAACAGAAAATTTGATAAGACTTTTACTAGAAGCCAGAGATATTAAGCTCTTAGAAAAAGAAATGAAAAATGTTGTGGA
GTTTTTTAAGAAAGCTTTAA

Downstream 100 bases:

>100_bases
TGATTATTATTTTTGGATTAAATGGGTGCATTATTTGGCATTTGTTTCTTGGATGGCGGGTCTTTTTTATTTACCTCGTC
TTTTTGTGTATCATGCTGAA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MAKTFKFIFYFWGAFVLVFALDQWVKSLTLAGFRWQSEYLDLTYALNTGVAFSMLSFLEHNLKYLHLALIGVLFIYLFWQ
RTLLKTHSIAFGMMLGAGVSNLLDRFIHGGVVDMFFWHKWFNFAIFNVADVMINISVALILIQEIFKKRKKDDRMD

Sequences:

>Translated_156_residues
MAKTFKFIFYFWGAFVLVFALDQWVKSLTLAGFRWQSEYLDLTYALNTGVAFSMLSFLEHNLKYLHLALIGVLFIYLFWQ
RTLLKTHSIAFGMMLGAGVSNLLDRFIHGGVVDMFFWHKWFNFAIFNVADVMINISVALILIQEIFKKRKKDDRMD
>Mature_155_residues
AKTFKFIFYFWGAFVLVFALDQWVKSLTLAGFRWQSEYLDLTYALNTGVAFSMLSFLEHNLKYLHLALIGVLFIYLFWQR
TLLKTHSIAFGMMLGAGVSNLLDRFIHGGVVDMFFWHKWFNFAIFNVADVMINISVALILIQEIFKKRKKDDRMD

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=120, Percent_Identity=32.5, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18327; Mature: 18196

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTFKFIFYFWGAFVLVFALDQWVKSLTLAGFRWQSEYLDLTYALNTGVAFSMLSFLEH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLKYLHLALIGVLFIYLFWQRTLLKTHSIAFGMMLGAGVSNLLDRFIHGGVVDMFFWHKW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
FNFAIFNVADVMINISVALILIQEIFKKRKKDDRMD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AKTFKFIFYFWGAFVLVFALDQWVKSLTLAGFRWQSEYLDLTYALNTGVAFSMLSFLEH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLKYLHLALIGVLFIYLFWQRTLLKTHSIAFGMMLGAGVSNLLDRFIHGGVVDMFFWHKW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
FNFAIFNVADVMINISVALILIQEIFKKRKKDDRMD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA